1. Social Pharmacy

In the last 5 years: Research projects 4. Thesis directed 19. Publications derived from the thesis 35.

Team: • Fernando Martinez Martinez. Associate Professor • Miguel Angel Calleja Hernandez, Chief Pharmacy Service . Hospital Universitario Virgen de las Nieves • Cebrian Antonio Arcos, Associate Professor • Francisco M. Ocaña Peinado, Associate Professor • Maria Dolores López Cabezas, Associate Professor • Maria Isabel Baena Parejo, Pharmaceutical Care Research Group, University of Granada • Emilio García Jiménez, Pharmaceutical Care Research Group, University of Granada

1.1 . Pharmaceutical Care: Fernando Martínez Martínez.

1.2 . Biostatistics Antonio Arcos Cebrian .

1.3 Pharmaceutical legislation: María Dolores López Cabezas.

2.- Drug Chemistry

In the last 5 years: Research projects 55. Thesis directed 25. Publications derived from the thesis 176.

Team: • M ª del Carmen González, Associate Professor • Bartolome Quintero Osso, Professor • Alberto Fernández Gutiérrez, Professor. • Natalia A. Navas Iglesias, Associate Professor • José María Álvarez Pez, Professor • Eva Maria Talavera Rodríguez, Professor • Luis Crovetto Gonzalez, Associate Professor • Angel Orte Gutiérrez, Associate Professor • María José Ruedas Rama, Associate Professor • Juan Niclós Gutiérrez, Professor • Josefa María González Pérez, Professor • Antonio Matilla Hernández, Asssociate Professor • Ricardo Navarrete Casas. • Contracted Doctor • Jose Luis Vilchez Quero, Professor • Miguel Angel Gallo Mezo, Professor • Joaquín Campos Rosa, Professor • Antonio Entrena Guadix, Professor • José Francisco Dominguez Seglar, Associate Professor • Juan Antonio Tamayo Torres, Associate Professor • Francisco Franco Montalbán, Associate Professor • Monica Diaz Gavilán, Associate Professor • José Antonio Gómez Vidal, Associate Professor

2.1. Photophysical of xanthene derivatives, fluorescence spectroscopy of single molecules, SMFS in homogeneous media and nanoemulsions. Application to the in vivo detection of phosphate in cells José María Álvarez Pez

2.5 2.2.Synthesis and photophysics dioxopyrrolidin -1- yl -4- (3-hydroxy- 6-oxo- 6H - xanthen -9- yl) -3- methylbenzoate . Application to the fluorescent detection of DNA hybridization. María José Ruedas Rama ,

2.3 . Structural changes in the formation of amyloid fibrils studied by fluorescence spectroscopy and single molecule imaging techniques lifetimes Angel Orte Gutierrez

2.4 Controlled expansion of polynuclear aggregates containing metal bridges (dimu-N3, N9- purinate)-metal: New molecular complexes nuclear oligo-, homo- and hetero- metallic. Juan Niclós Gutierrez.

2.5. Biomonitoring of chemical disruptors by advanced separative techniques. Jose Luis Vilchez Quero

2.6 . Drug design with antiproliferative activity: new improved choline kinase inhibitors as potent drugs with antiproliferative activity 2. Miguel Angel Gallo Mezo

2.7. New O, N- Acyclic acetals of 5-fluorouracil and purine derivatives di - and sri -substituted as Pharmacological Tools for the Treatment of Cancer Stem Cells. Joaquín Campos Rosa

2.8 . Synthesis of glycopeptides inhibitors of protein-protein interactions with neuroprotective activity. Juan Antonio Tamayo Torres

2.9 . Characterization of the antitumor activity of novel inhibitors of histone deacetylase Joseph A. Gómez Vidal

2.10 . Development of drugs for the treatment of primary hyperoxaluria . Monica Diaz Gavilan.

3 - . Medicament Technology

In the last 5 years: Research projects 38 . Thesis directed 17. Publications derived from the thesis 83.

Team: • Rafael Delgado Calvo -Flores, Professor • Eduardo Ortega Bernaldo de Quirós, Associate Professor • Jesus Párraga Martinez, Associate Professor • Gabriel Delgado Calvo -Flores, Associate Professor • Juan Manuel Martin Garcia, Associate Professor • M ª Adolfina Ruiz Martínez, Professor • Visitation Gallardo Lara, Associate Professor • M ª Teresa Marín Boscá, Associate Professor • M ª Victoria Margarit Bellver, Associate Professor • Caesar Vanity Iborra, Associate Professor • Pilar Cerezo González, Assistant Professor • Claro Ignacio Sainz Díaz, CSIC Research Scientist • Carola Aguzzi, Assistant Professor .

3.1 Analysis of soil materials and peloids (medicinal mud). Rafael Delgado Calvo-Flores

3.2 Microbiological decontamination phosphogypsum Uranium and Cadmium Contaminated. Eduardo Ortega Bernaldo de Quirós

3.3. Metal nanoparticles functionalised with fluorescent organic molecules. Biomedical Applications M ª Martínez Ruiz Adolfina

3.4. Technological parameters and formulation effects on the release of theophylline tablets lipid matrix M ª Teresa Marín Boscá

3.5. Application of nanomaterials clays as controlled release drug. Cesar Viseras Iborra

3.6 . Drug stability biotechnology nature (and chemistry) under normal hospital use Natalia Africa Navas Iglesias.

4 - New therapeutic targets

In the last 5 years: Research projects 63. Thesis directed 14. Publications derived from the thesis 51 .

Team: • Maria del Carmen Ramirez Tortosa, Professor • Rafael Salto González , Professor • Alberto Manuel Vargas Morales, Professor • Antonio Sanchez Pozo, Professor • Joaquina Martín Sánchez, Professor • Francisco Morillas Márquez, Professor • Rocío Benítez Rodríguez, Professor • F. Javier Adroher Auroux, Professor • Adela Valero Lopez, Professor • Francisco Gamarro Conde, CSIC Researcher , Institute of Parasitology and Biomedicine López Neira , Higher Council for Scientific Research • Carlos Manuel Lopez, CSIC Researcher , Institute Parasitology and Biomedicine López Neira , Higher Council for Scientific Research • Alfredo Berzal Herranz . Research Scientist , Institute of Parasitology and Biomedicine López Neira , Higher Council for Scientific Research • M ª Francisca Vicente Perez, Area Manager, Screening and Validation of targets, MEDINA • Olga Genilloud Rodriguez, Scientific Director, MEDINA . • José Tormo Rubén Beltrán , Associate Head of Department , Chemistry, MEDINA .

4.1.Analysis the gene expression profile in response to chemotherapy and their relation to oxidative stress in breast cancer. Maria del Carmen Ramirez Tortosa,

4.2.Evaluación new biological agents based on specific transfection vinyl sulfones Rafael Salto Gonzalez

4.3.Leishmaniosis and Anisakiosis. Joaquina Martín Sánchez

4.4. Leishmaniasis treatment: study of combinatorial search and drug resistance markers Francisco Gamarro Conde,

4.5.Biomarker development and useful molecules in immunotherapy against diseases caused by parasites, such as Chagas disease and leishmaniasis protozoa. Carlos Manuel Lopez

4.6.Circularization of Genomic RNA of Virus Hepatitis C and potential use as therapeutic target. Alfredo Berzal Herranz .

4.7. Microbial and metagenomics diversity. Maria Francisca Vicente Pérez

4.8.New Antibiotics against Gram negative multiply-resistant and Enhancers Drugs carbapenems activity. José Rubén Tormo Beltran

4.9.Oxidative stress. Bartolome Quintero,

4.10. Functional foods. Alberto Fernández Gutiérrez