Publicaciones resultantes de Tesis Doctorales

Curso 2016/2017

  • VALENZUELA MEMBRIVES, MARÍA DEL MAR

Del Mar Valenzuela-Membrives M, Perea-García F, Sanchez-Palencia A, Ruiz-Cabello F, Gómez-Morales M, Miranda-León MT, Galindo-Angel I, Fárez-Vidal ME. Progressive changes in composition of lymphocytes in lung tissues from patients with non-small-cell lung cancer. Oncotarget. 2016 Nov 1;7(44):71608-71619. doi: 10.18632/oncotarget.12264.

  • MUÑOZ-COBO BELART, JUAN PABLO

Sánchez-Hernández N, Prieto-Sánchez S, Moreno-Castro C, Muñoz-Cobo JP, El Yousfi Y, Boyero-Corral S, Suñé-Pou M, Hernández-Munain C, Suñé C. Targeting proteins to RNA transcription and processing sites within the nucleus. Int J Biochem Cell Biol. 2017 Oct;91(Pt B):194-202. doi: 10.1016/j.biocel.2017.06.001.

Muñoz-Cobo JP, Sánchez-Hernández N, Gutiérrez S, El Yousfi Y, Montes M, Gallego C, Hernández-Munain C, Suñé C. Transcriptional Elongation Regulator 1 Affects Transcription and Splicing of Genes Associated with Cellular Morphology and Cytoskeleton Dynamics and Is Required for Neurite Outgrowth in Neuroblastoma Cells and Primary Neuronal Cultures. Mol Neurobiol. 2017 Dec;54(10):7808-7823. doi: 10.1007/s12035-016-0284-6.

  • CABELLO DONAIRE, MARÍA

Cabello-Donayre M, Cabello-Donayre I, Guerra D, Orrego LM, Morales JC, Cautain B, Vicente F, Pérez-Victoria JM. A yeast-based high-throughput screen identifies inhibitors of trypanosomatid HRG heme transporters with potent leishmanicidal and trypanocidal activity. Int J Antimicrob Agents. 2024 Mar;63(3):107092. doi: 10.1016/j.ijantimicag.2024.107092.

Cabello-Donayre M, Orrego LM, Herráez E, García-Hernández R, Pérez-Victoria JM. New Insights on Heme Uptake in Leishmania spp. Int J Mol Sci. 2022 Sep 10;23(18):10501. doi: 10.3390/ijms231810501.

Perner J, Hatalova T, Cabello-Donayre M, Urbanova V, Sojka D, Frantova H, Hartmann D, Jirsova D, Pérez-Victoria JM, Kopacek P. Haem-responsive gene transporter enables mobilization of host haem in ticks. Open Biol. 2021 Sep;11(9):210048. doi: 10.1098/rsob.210048.

Orrego LM, Cabello-Donayre M, Vargas P, Martínez-García M, Sánchez C, Pineda-Molina E, Jiménez M, Molina R, Pérez-Victoria JM. Heme synthesis through the life cycle of the heme auxotrophic parasite Leishmania major. FASEB J. 2019 Dec;33(12):13367-13385. doi: 10.1096/fj.201901274RR.

Cabello-Donayre M, Orrego LM, Herráez E, Vargas P, Martínez-García M, Campos-Salinas J, Pérez-Victoria I, Vicente B, Marín JJG, Pérez-Victoria JM. Leishmania heme uptake involves LmFLVCRb, a novel porphyrin transporter essential for the parasite. Cell Mol Life Sci. 2020 May;77(9):1827-1845. doi: 10.1007/s00018-019-03258-3.

Cabello-Donayre M, Malagarie-Cazenave S, Campos-Salinas J, Gálvez FJ, Rodríguez-Martínez A, Pineda-Molina E, Orrego LM, Martínez-García M, Sánchez-Cañete MP, Estévez AM, Pérez-Victoria JM. Trypanosomatid parasites rescue heme from endocytosed hemoglobin through lysosomal HRG transporters. Mol Microbiol. 2016 Sep;101(6):895-908. doi: 10.1111/mmi.13430.

Martínez-García M, Campos-Salinas J, Cabello-Donayre M, Pineda-Molina E, Gálvez FJ, Orrego LM, Sánchez-Cañete MP, Malagarie-Cazenave S, Koeller DM, Pérez-Victoria JM. LmABCB3, an atypical mitochondrial ABC transporter essential for Leishmania major virulence, acts in heme and cytosolic iron/sulfur clusters biogenesis. Parasit Vectors. 2016 Jan 5;9:7. doi: 10.1186/s13071-015-1284-5.

Curso 2017/2018

  • ROBLES SÁNCHEZ, CÁNDIDO

Sáez-Lara MJ, Robles-Sanchez C, Ruiz-Ojeda FJ, Plaza-Diaz J, Gil A. Effects of Probiotics and Synbiotics on Obesity, Insulin Resistance Syndrome, Type 2 Diabetes and Non-Alcoholic Fatty Liver Disease: A Review of Human Clinical Trials. Int J Mol Sci. 2016 Jun 13;17(6):928. doi: 10.3390/ijms17060928.

Plaza-Díaz J, Robles-Sánchez C, Abadía-Molina F, Morón-Calvente V, Sáez-Lara MJ, Ruiz-Bravo A, Jiménez-Valera M, Gil Á, Gómez-Llorente C, Fontana L. Adamdec1, Ednrb and Ptgs1/Cox1, inflammation genes upregulated in the intestinal mucosa of obese rats, are downregulated by three probiotic strains. Sci Rep. 2017 May 16;7(1):1939. doi: 10.1038/s41598-017-02203-3.

Plaza-Díaz J, Robles-Sánchez C, Abadía-Molina F, Sáez-Lara MJ, Vilchez-Padial LM, Gil Á, Gómez-Llorente C, Fontana L. Gene expression profiling in the intestinal mucosa of obese rats administered probiotic bacteria. Sci Data. 2017 Dec 12;4:170186. doi: 10.1038/sdata.2017.186.

Álvarez-Mercado AI, Navarro-Oliveros M, Robles-Sánchez C, Plaza-Díaz J, Sáez-Lara MJ, Muñoz-Quezada S, Fontana L, Abadía-Molina F. Microbial Population Changes and Their Relationship with Human Health and Disease. Microorganisms. 2019 Mar 3;7(3):68. doi: 10.3390/microorganisms7030068.

Rodriguez J, Neyrinck AM, Zhang Z, Seethaler B, Nazare JA, Robles Sánchez C, Roumain M, Muccioli GG, Bindels LB, Cani PD, Maquet V, Laville M, Bischoff SC, Walter J, Delzenne NM. Metabolite profiling reveals the interaction of chitin-glucan with the gut microbiota. Gut Microbes. 2020 Nov 9;12(1):1810530. doi: 10.1080/19490976.2020.1810530.

  • PEREA GARCÍA, FRANCISCO JAVIER

Perea F, Bernal M, Sánchez-Palencia A, Carretero J, Torres C, Bayarri C, Gómez-Morales M, Garrido F, Ruiz-Cabello F. The absence of HLA class I expression in non-small cell lung cancer correlates with the tumor tissue structure and the pattern of T cell infiltration. Int J Cancer. 2017 Feb 15;140(4):888-899. doi: 10.1002/ijc.30489.

Garrido F, Perea F, Bernal M, Sánchez-Palencia A, Aptsiauri N, Ruiz-Cabello F. The Escape of Cancer from T Cell-Mediated Immune Surveillance: HLA Class I Loss and Tumor Tissue Architecture. Vaccines (Basel). 2017 Feb 27;5(1):7. doi: 10.3390/vaccines5010007.

Perea F, Sánchez-Palencia A, Gómez-Morales M, Bernal M, Concha Á, García MM, González-Ramírez AR, Kerick M, Martin J, Garrido F, Ruiz-Cabello F, Aptsiauri N. HLA class I loss and PD-L1 expression in lung cancer: impact on T-cell infiltration and immune escape. Oncotarget. 2017 Dec 19;9(3):4120-4133. doi: 10.18632/oncotarget.23469.

Garrido MA, Perea F, Vilchez JR, Rodríguez T, Anderson P, Garrido F, Ruiz-Cabello F, Aptsiauri N. Copy Neutral LOH Affecting the Entire Chromosome 6 Is a Frequent Mechanism of HLA Class I Alterations in Cancer. Cancers (Basel). 2021 Oct 9;13(20):5046. doi: 10.3390/cancers13205046.

Molina-Alejandre M, Perea F, Calvo V, Martinez-Toledo C, Nadal E, Sierra-Rodero B, Casarrubios M, Casal-Rubio J, Martinez-Martí A, Insa A, Massuti B, Viteri S, Barneto Aranda I, Rodriguez-Abreu D, de Castro J, Martínez JM, Cobo M, Wistuba II, Parra ER, Martín-López J, Megías D, Muñoz-Viana R, Garrido F, Aptsiauri N, Ruiz-Cabello F, Provencio M, Cruz-Bermúdez A. Perioperative chemoimmunotherapy induces strong immune responses and long-term survival in patients with HLA class I-deficient non-small cell lung cancer. J Immunother Cancer. 2024 Oct 20;12(10):e009762. doi: 10.1136/jitc-2024-009762.

  • FERNÁNDEZ COIRA, ISABEL

Coira IF, Rufino-Palomares EE, Romero OA, Peinado P, Metheetrairut C, Boyero-Corral L, Carretero J, Farez-Vidal E, Cuadros M, Reyes-Zurita FJ, Lupiáñez JA, Sánchez-Cespedes M, Slack FJ, Medina PP. Expression inactivation of SMARCA4 by microRNAs in lung tumors. Hum Mol Genet. 2015 Mar 1;24(5):1400-9. doi: 10.1093/hmg/ddu554.

Martin-Padron J, Boyero L, Rodriguez MI, Andrades A, Díaz-Cano I, Peinado P, Baliñas-Gavira C, Alvarez-Perez JC, Coira IF, Fárez-Vidal ME, Medina PP. Plakophilin 1 enhances MYC translation, promoting squamous cell lung cancer. Oncogene. 2020 Aug;39(32):5479-5493. doi: 10.1038/s41388-019-1129-3.

  • PEREA MARTÍNEZ, ANA

Perea A, Manzano JI, Castanys S, Gamarro F. The LABCG2 Transporter from the Protozoan Parasite Leishmania Is Involved in Antimony Resistance. Antimicrob Agents Chemother. 2016 May 23;60(6):3489-96. doi: 10.1128/AAC.02813-15.

Manzano JI, Perea A, León-Guerrero D, Campos-Salinas J, Piacenza L, Castanys S, Gamarro F. Leishmania LABCG1 and LABCG2 transporters are involved in virulence and oxidative stress: functional linkage with autophagy. Parasit Vectors. 2017 May 30;10(1):267. doi: 10.1186/s13071-017-2198-1.

Perea A, Manzano JI, Kimura Y, Ueda K, Castanys S, Gamarro F. Leishmania LABCG2 transporter is involved in ATP-dependent transport of thiols. Biochem J. 2018 Jan 2;475(1):87-97. doi: 10.1042/BCJ20170685.

  • SALINERO BACHILLER, MARÍA

Jiménez-Pacheco A, Salinero-Bachiller M, Iribar MC, López-Luque A, Miján-Ortiz JL, Peinado JM. Furan and p-xylene as candidate biomarkers for prostate cancer. Urol Oncol. 2018 May;36(5):243.e21-243.e27. doi: 10.1016/j.urolonc.2017.12.026. Epub 2018 Feb 1.

  • MARTINEZ GARCÍA, MARTA

Fernandez-Pastor I, Martínez-García M, Medina-O'Donnell M, Rivas F, Martinez A, Pérez-Victoria JM, Parra A. Semisynthesis of ω-Hydroxyalkylcarbonate Derivatives of Hydroxytyrosol as Antitrypanosome Agents. J Nat Prod. 2018 Sep 28;81(9):2075-2082. doi: 10.1021/acs.jnatprod.8b00431.

Orrego LM, Cabello-Donayre M, Vargas P, Martínez-García M, Sánchez C, Pineda-Molina E, Jiménez M, Molina R, Pérez-Victoria JM. Heme synthesis through the life cycle of the heme auxotrophic parasite Leishmania major. FASEB J. 2019 Dec;33(12):13367-13385. doi: 10.1096/fj.201901274RR.

  • MOLINA FERNÁNDEZ, DOLORES

Molina-Fernández D, Rubio-Calvo D, Adroher FJ, Benítez R. Molecular epidemiology of Anisakis spp. in blue whiting Micromesistius poutassou in eastern waters of Spain, western Mediterranean Sea. Int J Food Microbiol. 2018 Oct 3;282:49-56. doi: 10.1016/j.ijfoodmicro.2018.05.026.

Molina-Fernández D, Benítez R, Adroher FJ, Malagón D. Differential proteolytic activity in Anisakis simplex s.s. and Anisakis pegreffii, two sibling species from the complex Anisakis simplex s.l., major etiological agents of anisakiasis. Acta Trop. 2019 Jul;195:44-50. doi: 10.1016/j.actatropica.2019.04.003.

Torralbo-Ramírez V, Molina-Fernández D, Malagón D, Benítez R, Adroher FJ. Differential Cleaving of Specific Substrates for Cathepsin-Like Activity Shows Cysteine and Serine Protease Activities and a Differential Profile Between Anisakis simplex s.s. and Anisakis pegreffii, Sibling Species Major Etiologic Agents of Anisakiasis. Foodborne Pathog Dis. 2019 Nov;16(11):744-751. doi: 10.1089/fpd.2019.2633.

  • ARCARI ROCCA, TALIA

Arcari T, Manzano JI, Gamarro F. ABCI3 Is a New Mitochondrial ABC Transporter from Leishmania major Involved in Susceptibility to Antimonials and Infectivity. Antimicrob Agents Chemother. 2017 Nov 22;61(12):e01115-17. doi: 10.1128/AAC.01115-17.

Curso 2018/2019

  • RIVERO RÍOS, MARÍA DEL PILAR

Rivero-Ríos P, Gómez-Suaga P, Fernández B, Madero-Pérez J, Schwab AJ, Ebert AD, Hilfiker S. Alterations in late endocytic trafficking related to the pathobiology of LRRK2-linked Parkinson's disease. Biochem Soc Trans. 2015 Jun;43(3):390-5. doi: 10.1042/BST20140301.

Rivero-Ríos P, Madero-Pérez J, Fernández B, Hilfiker S. Targeting the Autophagy/Lysosomal Degradation Pathway in Parkinson's Disease. Curr Neuropharmacol. 2016;14(3):238-49. doi: 10.2174/1570159×13666151030103027.

Blanca Ramírez M, Madero-Perez J, Rivero-Rios P, Martinez-Salvador M, Lara Ordonez AJ, Fernandez B, Fdez E, Hilfiker S. LRRK2 and Parkinson's Disease: From Lack of Structure to Gain of Function. Curr Protein Pept Sci. 2017;18(7):677-686. doi: 10.2174/1389203717666160311121748.

Rivero-Ríos P, Fernández B, Madero-Pérez J, Lozano MR, Hilfiker S. Two-Pore Channels and Parkinson's Disease: Where's the Link? Messenger (Los Angel). 2016 Jun 1;5(1-2):67-75. doi: 10.1166/msr.2016.1051.

Rivero-Ríos P, Romo-Lozano M, Madero-Pérez J, Thomas AP, Biosa A, Greggio E, Hilfiker S. The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A. J Biol Chem. 2019 Mar 29;294(13):4738-4758. doi: 10.1074/jbc.RA118.005008.

Rivero-Ríos P, Romo-Lozano M, Fasiczka R, Naaldijk Y, Hilfiker S. LRRK2-Related Parkinson's Disease Due to Altered Endolysosomal Biology With Variable Lewy Body Pathology: A Hypothesis. Front Neurosci. 2020 Jun 4;14:556. doi: 10.3389/fnins.2020.00556. Rivero-Ríos P, Romo-Lozano M, Fernández B, Fdez E, Hilfiker S. Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations. Cells. 2020 Jul 17;9(7):1719. doi: 10.3390/cells9071719.

  • MENDOZA TESARIK, RAQUEL NATALIA

Altmäe S, Mendoza-Tesarik R, Mendoza C, Mendoza N, Cucinelli F, Tesarik J. Effect of Growth Hormone on Uterine Receptivity in Women With Repeated Implantation Failure in an Oocyte Donation Program: A Randomized Controlled Trial. J Endocr Soc. 2017 Dec 19;2(1):96-105. doi: 10.1210/js.2017-00359. Erratum in: J Endocr Soc. 2018 Jan 08;2(2):133. doi: 10.1210/js.2018-00006.

Mendoza-Tesarik R, Tesarik J. Usefulness of individualized FSH, LH and GH dosing in ovarian stimulation of women with low ovarian reserve. Hum Reprod. 2018 May 1;33(5):981-982. doi: 10.1093/humrep/dey063.

Tesarik J, Mendoza-Tesarik R. Patient-tailored luteal phase support with progesterone may avoid unnecessary oocyte donation failures. Reprod Biomed Online. 2019 Nov;39(5):877. doi: 10.1016/j.rbmo.2019.08.006

Mendoza N, Galan MI, Molina C, Mendoza-Tesarik R, Conde C, Mazheika M, Diaz-Ropero MP, Fonolla J, Tesarik J, Olivares M. High dose of d-chiro-inositol improves oocyte quality in women with polycystic ovary syndrome undergoing ICSI: a randomized controlled trial. Gynecol Endocrinol. 2020 May;36(5):398-401. doi: 10.1080/09513590.2019.1681959.

Tesarik J, Galán-Lázaro M, Conde-López C, Chiara-Rapisarda AM, Mendoza-Tesarik R. The Effect of GH Administration on Oocyte and Zygote Quality in Young Women With Repeated Implantation Failure After IVF. Front Endocrinol (Lausanne). 2020 Sep 29;11:519572. doi: 10.3389/fendo.2020.519572

Tesarik J, Conde-López C, Galán-Lázaro M, Mendoza-Tesarik R. Luteal Phase in Assisted Reproductive Technology. Front Reprod Health. 2020 Dec 7;2:595183. doi: 10.3389/frph.2020.595183.

Tesarik J, Galán-Lázaro M, Mendoza-Tesarik R. Ovarian Aging: Molecular Mechanisms and Medical Management. Int J Mol Sci. 2021 Jan 29;22(3):1371. doi: 10.3390/ijms22031371.

Tesarik J, Galán-Lázaro M, Mendoza N, Mendoza-Tesarik R. Double HCG trigger improves recovery of oocytes in women with a paucifollicular response to ovarian stimulation: A pilot study. Int J Gynaecol Obstet. 2022 Apr;157(1):149-153. doi: 10.1002/ijgo.13735

Tesarik J, Mendoza-Tesarik R. Molecular Clues to Understanding Causes of Human-Assisted Reproduction Treatment Failures and Possible Treatment Options. Int J Mol Sci. 2022 Sep 8;23(18):10357. doi: 10.3390/ijms231810357.

Tesarik J, Mendoza-Tesarik R. Patient-tailored reproductive health care. Front Reprod Health. 2022 Jul 18;4:917159. doi: 10.3389/frph.2022.917159.

  • ORREGO ZAPATA, LINA MARÍA

Cabello-Donayre M, Orrego LM, Herráez E, Vargas P, Martínez-García M, Campos-Salinas J, Pérez-Victoria I, Vicente B, Marín JJG, Pérez-Victoria JM. Leishmania heme uptake involves LmFLVCRb, a novel porphyrin transporter essential for the parasite. Cell Mol Life Sci. 2020 May;77(9):1827-1845. doi: 10.1007/s00018-019-03258-3.

Orrego LM, Cabello-Donayre M, Vargas P, Martínez-García M, Sánchez C, Pineda-Molina E, Jiménez M, Molina R, Pérez-Victoria JM. Heme synthesis through the life cycle of the heme auxotrophic parasite Leishmania major. FASEB J. 2019 Dec;33(12):13367-13385. doi: 10.1096/fj.201901274RR.

Cabello-Donayre M, Orrego LM, Herráez E, García-Hernández R, Pérez-Victoria JM. New Insights on Heme Uptake in Leishmania spp. Int J Mol Sci. 2022 Sep 10;23(18):10501. doi: 10.3390/ijms231810501.

Curso 2019/2020

  • ROJAS GONZÁLEZ, JOSÉ ANTONIO

Rojas-González JA, Soto-Súarez M, García-Díaz Á, Romero-Puertas MC, Sandalio LM, Mérida Á, Thormählen I, Geigenberger P, Serrato AJ, Sahrawy M. Disruption of both chloroplastic and cytosolic FBPase genes results in a dwarf phenotype and important starch and metabolite changes in Arabidopsis thaliana. J Exp Bot. 2015 May;66(9):2673-89. doi: 10.1093/jxb/erv062.

Soto-Suárez M, Serrato AJ, Rojas-González JA, Bautista R, Sahrawy M. Transcriptomic and proteomic approach to identify differentially expressed genes and proteins in Arabidopsis thaliana mutants lacking chloroplastic 1 and cytosolic FBPases reveals several levels of metabolic regulation. BMC Plant Biol. 2016 Dec 1;16(1):258. doi: 10.1186/s12870-016-0945-7.

Talbi, S., Rojas, J. A., Sahrawy, M., Rodríguez-Serrano, M., Cárdenas, K. E., Debouba, M., & Sandalio, L. M. (2020, August). Effect of drought on growth, photosynthesis and total antioxidant capacity of the saharan plant Oudeneya africana. Environmental and Experimental Botany. Elsevier BV. http://doi.org/10.1016/j.envexpbot.2020.104099

  • MARTÍNEZ ARRIBAS, BLANCA

Martínez-Arribas B, Requena CE, Pérez-Moreno G, Ruíz-Pérez LM, Vidal AE, González-Pacanowska D. DCTPP1 prevents a mutator phenotype through the modulation of dCTP, dTTP and dUTP pools. Cell Mol Life Sci. 2020 Apr;77(8):1645-1660. doi: 10.1007/s00018-019-03250-x.

  • SAURA REBOLLAR, ANDREU

Saura A, Iribarren PA, Rojas-Barros D, Bart JM, López-Farfán D, Andrés-León E, Vidal-Cobo I, Boehm C, Alvarez VE, Field MC, Navarro M. SUMOylated SNF2PH promotes variant surface glycoprotein expression in bloodstream trypanosomes. EMBO Rep. 2019 Dec 5;20(12):e48029. doi: 10.15252/embr.201948029

Iribarren PA, Di Marzio LA, Berazategui MA, Saura A, Coria L, Cassataro J, Rojas F, Navarro M, Alvarez VE. Depolymerization of SUMO chains induces slender to stumpy differentiation in T. brucei bloodstream parasites. PLoS Pathog. 2024 Apr 18;20(4):e1012166. doi: 10.1371/journal.ppat.1012166.

Ferrins L, Diaz R, Cordon-Obras C, Rojas-Barros D, Quotadamo A, Oehme DP, Ceballos-Pérez G, Swaminathan U, Pérez-Moreno G, Bosch-Navarrete C, García-Hernández R, Gomez-Liñan C, Saura A, Ruiz-Perez LM, Gamarro F, Martinez-Martinez MS, Manzano P, González-Pacanowska D, Navarro M, Pollastri MP. Pharmacophore Identification and Structure-Activity Relationship Analysis of a Series of Substituted Azaindoles as Inhibitors of Trypanosoma brucei. J Med Chem. 2024 Aug 22;67(16):13985-14006. doi: 10.1021/acs.jmedchem.4c00785

  • YAGÜE CAPILLA, MIRIAM

Yagüe-Capilla M, García-Caballero D, Aguilar-Pereyra F, Castillo-Acosta VM, Ruiz-Pérez LM, Vidal AE, González-Pacanowska D. Base excision repair plays an important role in the protection against nitric oxide- and in vivo-induced DNA damage in Trypanosoma brucei. Free Radic Biol Med. 2019 Feb 1;131:59-71. doi: 10.1016/j.freeradbiomed.2018.11.025. Huang CY, Yagüe-Capilla M, González-Pacanowska D, Chang ZF. Quantitation of deoxynucleoside triphosphates by click reactions. Sci Rep. 2020 Jan 17;10(1):611. doi: 10.1038/s41598-020-57463-3.

Yagüe-Capilla M, Castillo-Acosta VM, Bosch-Navarrete C, Ruiz-Pérez LM, González-Pacanowska D. A Mitochondrial Orthologue of the dNTP Triphosphohydrolase SAMHD1 Is Essential and Controls Pyrimidine Homeostasis in Trypanosoma brucei. ACS Infect Dis. 2021 Feb 12;7(2):318-332. doi: 10.1021/acsinfecdis.0c00551.

Vidal AE, Yagüe-Capilla M, Martínez-Arribas B, García-Caballero D, Ruiz-Pérez LM, González-Pacanowska D. Inosine triphosphate pyrophosphatase from Trypanosoma brucei cleanses cytosolic pools from deaminated nucleotides. Sci Rep. 2022 Apr 18;12(1):6408. doi: 10.1038/s41598-022-10149-4.

  • MARTÍN PADRÓN, JOEL

Martin-Padron J, Boyero L, Rodriguez MI, Andrades A, Díaz-Cano I, Peinado P, Baliñas-Gavira C, Alvarez-Perez JC, Coira IF, Fárez-Vidal ME, Medina PP. Plakophilin 1 enhances MYC translation, promoting squamous cell lung cancer. Oncogene. 2020 Aug;39(32):5479-5493. doi: 10.1038/s41388-019-1129-3.

Boyero L, Martin-Padron J, Fárez-Vidal ME, Rodriguez MI, Andrades Á, Peinado P, Arenas AM, Ritoré-Salazar F, Alvarez-Perez JC, Cuadros M, Medina PP. PKP1 and MYC create a feedforward loop linking transcription and translation in squamous cell lung cancer. Cell Oncol (Dordr). 2022 Apr;45(2):323-332. doi: 10.1007/s13402-022-00660-1.

Curso 2020/2021

  • AGUILAR ROMERO, INÉS MARÍA

Aguilar-Romero I, Romero E, Wittich RM, van Dillewijn P. Bacterial ecotoxicity and shifts in bacterial communities associated with the removal of ibuprofen, diclofenac and triclosan in biopurification systems. Sci Total Environ. 2020 Nov 1;741:140461. doi: 10.1016/j.scitotenv.2020.140461.

Aguilar-Romero I, De la Torre-Zúñiga J, Quesada JM, Haïdour A, O'Connell G, McAmmond BM, Van Hamme JD, Romero E, Wittich RM, van Dillewijn P. Effluent decontamination by the ibuprofen-mineralizing strain, Sphingopyxis granuli RW412: Metabolic processes. Environ Pollut. 2021 Apr 1;274:116536. doi: 10.1016/j.envpol.2021.116536.

Aguilar-Romero I, van Dillewijn P, Nesme J, Sørensen SJ, Nogales R, Delgado-Moreno L, Romero E. A novel and affordable bioaugmentation strategy with microbial extracts to accelerate the biodegradation of emerging contaminants in different media. Sci Total Environ. 2022 Aug 15;834:155234. doi: 10.1016/j.scitotenv.2022.155234.

  • BALIÑAS GAVIRA, CARLOS

Baliñas-Gavira C, Rodríguez MI, Andrades A, Cuadros M, Álvarez-Pérez JC, Álvarez-Prado ÁF, de Yébenes VG, Sánchez-Hernández S, Fernández-Vigo E, Muñoz J, Martín F, Ramiro AR, Martínez-Climent JA, Medina PP. Frequent mutations in the amino-terminal domain of BCL7A impair its tumor suppressor role in DLBCL. Leukemia. 2020 Oct;34(10):2722-2735. doi: 10.1038/s41375-020-0919-5.

Patiño-Mercau JR, Baliñas-Gavira C, Andrades A, Benitez-Cantos MS, Rot AE, Rodriguez MI, Álvarez-Pérez JC, Cuadros M, Medina PP. BCL7A is silenced by hypermethylation to promote acute myeloid leukemia. Biomark Res. 2023 Mar 20;11(1):32. doi: 10.1186/s40364-023-00472-x.

  • PLESSELOVÁ, SIMONA

Reche-Perez FJ, Plesselova S, De Los Reyes-Berbel E, Ortega-Muñoz M, Lopez-Jaramillo FJ, Hernandez-Mateo F, Santoyo-Gonzalez F, Salto-Gonzalez R, Giron-Gonzalez MD. Single chain variable fragment fused to maltose binding protein: a modular nanocarrier platform for the targeted delivery of antitumorals. Biomater Sci. 2021 Mar 10;9(5):1728-1738. doi: 10.1039/d0bm01903h.

Ortega-Muñoz M, Plesselova S, Delgado AV, Santoyo-Gonzalez F, Salto-Gonzalez R, Giron-Gonzalez MD, Iglesias GR, López-Jaramillo FJ. Poly(ethylene-imine)-Functionalized Magnetite Nanoparticles Derivatized with Folic Acid: Heating and Targeting Properties. Polymers (Basel). 2021 May 15;13(10):1599. doi: 10.3390/polym13101599.

Plesselova S, Garcia-Cerezo P, Blanco V, Reche-Perez FJ, Hernandez-Mateo F, Santoyo-Gonzalez F, Giron-Gonzalez MD, Salto-Gonzalez R. Polyethylenimine-Bisphosphonate-Cyclodextrin Ternary Conjugates: Supramolecular Systems for the Delivery of Antineoplastic Drugs. J Med Chem. 2021 Aug 26;64(16):12245-12260. doi: 10.1021/acs.jmedchem.1c00887.

  • MARÍN ALEJO, MILAGROS

Marín M, Esteban FJ, Ramírez-Rodrigo H, Ros E, Sáez-Lara MJ. An integrative methodology based on protein-protein interaction networks for identification and functional annotation of disease-relevant genes applied to channelopathies. BMC Bioinformatics. 2019 Nov 12;20(1):565. doi: 10.1186/s12859-019-3162-1.

Marín M, Sáez-Lara MJ, Ros E, Garrido JA. Optimization of Efficient Neuron Models With Realistic Firing Dynamics. The Case of the Cerebellar Granule Cell. Front Cell Neurosci. 2020 Jul 14;14:161. doi: 10.3389/fncel.2020.00161.

Marín M, Cruz NC, Ortigosa EM, Sáez-Lara MJ, Garrido JA, Carrillo RR. On the Use of a Multimodal Optimizer for Fitting Neuron Models. Application to the Cerebellar Granule Cell. Front Neuroinform. 2021 Jun 3;15:663797. doi: 10.3389/fninf.2021.663797.

Curso 2021/2022

  • MORO BULNES, ANA

Moro-Bulnes A, Castillo-Acosta VM, Valente M, Carrero-Lérida J, Pérez-Moreno G, Ruiz-Pérez LM, González-Pacanowska D. Contribution of Cytidine Deaminase to Thymidylate Biosynthesis in Trypanosoma brucei: Intracellular Localization and Properties of the Enzyme. mSphere. 2019 Aug 7;4(4):e00374-19. doi: 10.1128/mSphere.00374-19.

  • PEINADO FERNÁNDEZ, PAOLA

Peinado P, Andrades A, Cuadros M, Rodriguez MI, Coira IF, Garcia DJ, Álvarez-Perez JC, Baliñas-Gavira C, Arenas AM, Patiño-Mercau JR, Sanjuan-Hidalgo J, Romero OA, Montuenga LM, Carretero J, Sanchez-Cespedes M, Medina PP. Comprehensive Analysis of SWI/SNF Inactivation in Lung Adenocarcinoma Cell Models. Cancers (Basel). 2020 Dec 10;12(12):3712. doi: 10.3390/cancers12123712.

Peinado P, Andrades A, Martorell-Marugán J, Haswell JR, Slack FJ, Carmona-Sáez P, Medina PP. The SWI/SNF complex regulates the expression of miR-222, a tumor suppressor microRNA in lung adenocarcinoma. Hum Mol Genet. 2021 Nov 16;30(23):2263-2271. doi: 10.1093/hmg/ddab187.

Peinado P, Andrades A, Cuadros M, Rodriguez MI, Coira IF, Garcia DJ, Benitez-Cantos MS, Cano C, Zarzuela E, Muñoz J, Loidi C, Saiz M, Medina PP. Multi-omic alterations of the SWI/SNF complex define a clinical subgroup in lung adenocarcinoma. Clin Epigenetics. 2022 Mar 17;14(1):42. doi: 10.1186/s13148-022-01261-3.

  • SÁNCHEZ MARTÍN, VICTORIA

Sanchez-Martin V, Schneider DA, Ortiz-Gonzalez M, Soriano-Lerma A, Linde-Rodriguez A, Perez-Carrasco V, Gutierrez-Fernandez J, Cuadros M, González C, Soriano M, Garcia-Salcedo JA. Targeting ribosomal G-quadruplexes with naphthalene-diimides as RNA polymerase I inhibitors for colorectal cancer treatment. Cell Chem Biol. 2021 Nov 18;28(11):1590-1601.e4. doi: 10.1016/j.chembiol.2021.05.021.

Sanchez-Martin V, Plaza-Calonge MDC, Soriano-Lerma A, Ortiz-Gonzalez M, Linde-Rodriguez A, Perez-Carrasco V, Ramirez-Macias I, Cuadros M, Gutierrez-Fernandez J, Murciano-Calles J, Rodríguez-Manzaneque JC, Soriano M, Garcia-Salcedo JA. Gallic Acid: A Natural Phenolic Compound Exerting Antitumoral Activities in Colorectal Cancer via Interaction with G-Quadruplexes. Cancers (Basel). 2022 May 26;14(11):2648. doi: 10.3390/cancers14112648.

  • GÓMEZ GARCÍA, INMACULADA MARÍA

Gómez, I., Thomas, M.C. (AC), …, López, M.C. (2/10) (2021) “Differential Expression of Immune Response Genes in Asymptomatic Chronic Chagas Disease Patients Versus Healthy Subjects”. Frontiers in cellular and infection microbiology. 11:722984. https://doi.org/10.3389/FCIMB.2021.722984

Gómez, I., López, M.C..., Thomas MC. Differential Expression Profile of genes involved in the immune response associated to progression of chronic Chagas disease. PLOS neglected Tropical Diseases (2023) Jul 13;17(7):e0011474. doi: 10.1371/journal.pntd.0011474.

Gómez I, Egui A, Palacios G, Carrilero B, Benítez C, Simón M, Segovia M, Carmelo E, López MC, Thomas MC. The expression of immune response genes in patients with chronic Chagas disease is shifted toward the levels observed in healthy subjects as a result of treatment with Benznidazole. Frontiers in Cellular and Infection Microbiology (2024Vol 14) https://doi.org/10.3389/fcimb.2024.1439714

  • ANDRADES DELGADO, ÁLVARO

Cuadros M, Andrades Á, Coira IF, Baliñas C, Rodríguez MI, Álvarez-Pérez JC, Peinado P, Arenas AM, García DJ, Jiménez P, Camós M, Jiménez-Velasco A, Medina PP. Expression of the long non-coding RNA TCL6 is associated with clinical outcome in pediatric B-cell acute lymphoblastic leukemia. Blood Cancer J. 2019 Nov 25;9(12):93. doi: 10.1038/s41408-019-0258-9.

Andrades A, Álvarez-Pérez JC, Patiño-Mercau JR, Cuadros M, Baliñas-Gavira C, Medina PP. Recurrent splice site mutations affect key diffuse large B-cell lymphoma genes. Blood. 2022 Apr 14;139(15):2406-2410. doi: 10.1182/blood.2021011708.

Andrades A, Peinado P, Alvarez-Perez JC, Sanjuan-Hidalgo J, García DJ, Arenas AM, Matia-González AM, Medina PP. SWI/SNF complexes in hematological malignancies: biological implications and therapeutic opportunities. Mol Cancer. 2023 Feb 21;22(1):39. doi: 10.1186/s12943-023-01736-8.

Curso 2022/2023

  • JANNUS, FATIN

Jannus F, Medina-O'Donnell M, Rivas F, Díaz-Ruiz L, Rufino-Palomares EE, Lupiáñez JA, Parra A, Reyes-Zurita FJ. A Diamine-PEGylated Oleanolic Acid Derivative Induced Efficient Apoptosis through a Death Receptor and Mitochondrial Apoptotic Pathway in HepG2 Human Hepatoma Cells. Biomolecules. 2020 Sep 28;10(10):1375. doi: 10.3390/biom10101375.

Galisteo A, Jannus F, García-García A, Aheget H, Rojas S, Lupiañez JA, Rodríguez-Diéguez A, Reyes-Zurita FJ, Quílez Del Moral JF. Diclofenac N-Derivatives as Therapeutic Agents with Anti-Inflammatory and Anti-Cancer Effect. Int J Mol Sci. 2021 May 11;22(10):5067. doi: 10.3390/ijms22105067

Jannus F, Medina-O'Donnell M, Neubrand VE, Marín M, Saez-Lara MJ, Sepulveda MR, Rufino-Palomares EE, Martinez A, Lupiañez JA, Parra A, Rivas F, Reyes-Zurita FJ. Efficient In Vitro and In Vivo Anti-Inflammatory Activity of a Diamine-PEGylated Oleanolic Acid Derivative. Int J Mol Sci. 2021 Jul 29;22(15):8158. doi: 10.3390/ijms22158158.

Jannus F, Sainz J, Reyes-Zurita FJ. Principal Bioactive Properties of Oleanolic Acid, Its Derivatives, and Analogues. Molecules. 2024 Jul 12;29(14):3291. doi: 10.3390/molecules29143291.

  • GALINDO ÁNGEL, INMACULADA

Galindo I, Gómez-Morales M, Díaz-Cano I, Andrades Á, Caba-Molina M, Miranda-León MT, Medina PP, Martín-Padron J, Fárez-Vidal ME. The value of desmosomal plaque-related markers to distinguish squamous cell carcinoma and adenocarcinoma of the lung. Ups J Med Sci. 2020 Feb;125(1):19-29. doi: 10.1080/03009734.2019.1692101.

  • GÓMEZ LIÑÁN, CLAUDIA

Gómez-Liñán C, Gómez-Díaz E, Ceballos-Pérez G, Fernández-Moya SM, Estévez AM. The RNA-binding protein RBP33 dampens non-productive transcription in trypanosomes. Nucleic Acids Res. 2022 Nov 28;50(21):12251-12265. doi: 10.1093/nar/gkac1123.

  • ARENAS MOLINA, ALBERTO MANUEL

Arenas AM, Cuadros M, Andrades A, García DJ, Coira IF, Rodríguez MI, Baliñas-Gavira C, Peinado P, Álvarez-Pérez JC, Medina PP. LncRNA DLG2-AS1 as a Novel Biomarker in Lung Adenocarcinoma. Cancers (Basel). 2020 Jul 28;12(8):2080. doi: 10.3390/cancers12082080.

Arenas AM, Ruiz-Jiménez JM, López-Hidalgo JL, Sanjuán-Hidalgo J, Medina PP. Defining the first bona fide cell model for SMARCA4-deficient, undifferentiated tumor. J Pathol. 2023 Sep;261(1):5-10. doi: 10.1002/path.6141.

  • CEBALLOS PÉREZ, GLORIA

Ceballos-Pérez G, Rico-Jiménez M, Gómez-Liñán C, Estévez AM. Role of the RNA-binding protein ZC3H41 in the regulation of ribosomal protein messenger RNAs in trypanosomes. Parasit Vectors. 2023 Mar 31;16(1):118. doi: 10.1186/s13071-023-05728-x.

Rico-Jiménez M, Ceballos-Pérez G, Gómez-Liñán C, Estévez AM. An RNA-binding protein complex regulates the purine-dependent expression of a nucleobase transporter in trypanosomes. Nucleic Acids Res. 2021 Apr 19;49(7):3814-3825. doi: 10.1093/nar/gkab181.

  • MORENO SAN JUAN, SARA

Aroca-Siendones MI, Moreno-SanJuan S, Puentes-Pardo JD, Verbeni M, Arnedo J, Escudero-Feliu J, García-Costela M, García-Robles A, Carazo Á, León J. Core Circadian Clock Proteins as Biomarkers of Progression in Colorectal Cancer. Biomedicines. 2021 Aug 6;9(8):967. doi: 10.3390/biomedicines9080967.

Moreno-SanJuan S, Puentes-Pardo JD, Casado J, Escudero-Feliu J, Khaldy H, Arnedo J, Carazo Á, León J. Agomelatine, a Melatonin-Derived Drug, as a New Strategy for the Treatment of Colorectal Cancer. Antioxidants (Basel). 2023 Apr 13;12(4):926. doi: 10.3390/antiox12040926.

Curso 2023/2024

  • GARCÍA GARCÍA, DANIEL JESÚS

Cuadros M, García DJ, Andrades A, Arenas AM, Coira IF, Baliñas-Gavira C, Peinado P, Rodríguez MI, Álvarez-Pérez JC, Ruiz-Cabello F, Camós M, Jiménez-Velasco A, Medina PP. LncRNA-mRNA Co-Expression Analysis Identifies AL133346.1/CCN2 as Biomarkers in Pediatric B-Cell Acute Lymphoblastic Leukemia. Cancers (Basel). 2020 Dec 17;12(12):3803. doi: 10.3390/cancers12123803.

Cuadros M, Andrades Á, Coira IF, Baliñas C, Rodríguez MI, Álvarez-Pérez JC, Peinado P, Arenas AM, García DJ, Jiménez P, Camós M, Jiménez-Velasco A, Medina PP. Expression of the long non-coding RNA TCL6 is associated with clinical outcome in pediatric B-cell acute lymphoblastic leukemia. Blood Cancer J. 2019 Nov 25;9(12):93. doi: 10.1038/s41408-019-0258-9.

  • LÓPEZ PÉREZ, DAVID

Lopez-Perez D, Prados-Lopez B, Galvez J, Leon J, Carazo A. Eosinophils in Colorectal Cancer: Emerging Insights into Anti-Tumoral Mechanisms and Clinical Implications. Int J Mol Sci. 2024 Jun 1;25(11):6098. doi: 10.3390/ijms25116098.

Lopez-Perez D, Redruello-Romero A, Garcia-Rubio J, Arana C, Garcia-Escudero LA, Tamayo F, Salmeron J, Galvez J, Leon J, Carazo Á. In Obese Patients With Type 2 Diabetes, Mast Cells in Omental Adipose Tissue Decrease the Surface Expression of CD45, CD117, CD203c, and FcϵRI. Front Endocrinol (Lausanne). 2022 Mar 15;13:818388. doi: 10.3389/fendo.2022.818388.

Lopez-Perez D, Redruello-Romero A, Garcia-Rubio J, Arana C, Garcia-Escudero LA, Tamayo F, Puentes-Pardo JD, Moreno-SanJuan S, Salmeron J, Blanco A, Galvez J, Leon J, Carazo Á. In Patients With Obesity, the Number of Adipose Tissue Mast Cells Is Significantly Lower in Subjects With Type 2 Diabetes. Front Immunol. 2021 May 21;12:664576. doi: 10.3389/fimmu.2021.664576.

Del Moral-Martinez M, Sánchez-Uceta P, Clemente-Gonzalez R, Moreno-SanJuan S, Puentes-Pardo JD, Khaldy H, Lopez-Perez D, Arnedo J, Casado J, Martínez-Heredia L, Carazo A, León J. iNOS-Produced Nitric Oxide from Cancer Cells as an Intermediate of Stemness Regulation by PARP-1 in Colorectal Cancer. Biomolecules. 2025 Jan 14;15(1):125. doi: 10.3390/biom15010125.

  • ROMO LOZANO, MARÍA

Rivero-Ríos P, Romo-Lozano M, Madero-Pérez J, Thomas AP, Biosa A, Greggio E, Hilfiker S. The G2019S variant of leucine-rich repeat kinase 2 (LRRK2) alters endolysosomal trafficking by impairing the function of the GTPase RAB8A. J Biol Chem. 2019 Mar 29;294(13):4738-4758. doi: 10.1074/jbc.RA118.005008.

Lara Ordónez AJ, Fernández B, Fdez E, Romo-Lozano M, Madero-Pérez J, Lobbestael E, Baekelandt V, Aiastui A, López de Munaín A, Melrose HL, Civiero L, Hilfiker S. RAB8, RAB10 and RILPL1 contribute to both LRRK2 kinase-mediated centrosomal cohesion and ciliogenesis deficits. Hum Mol Genet. 2019 Nov 1;28(21):3552-3568. doi: 10.1093/hmg/ddz201.

Rivero-Ríos P, Romo-Lozano M, Fasiczka R, Naaldijk Y, Hilfiker S. LRRK2-Related Parkinson's Disease Due to Altered Endolysosomal Biology With Variable Lewy Body Pathology: A Hypothesis. Front Neurosci. 2020 Jun 4;14:556. doi: 10.3389/fnins.2020.00556.

Rivero-Ríos P, Romo-Lozano M, Fernández B, Fdez E, Hilfiker S. Distinct Roles for RAB10 and RAB29 in Pathogenic LRRK2-Mediated Endolysosomal Trafficking Alterations. Cells. 2020 Jul 17;9(7):1719. doi: 10.3390/cells9071719.

  • MARTÍNEZ DIZ, SILVIA

Martinez-Diz S, Morales-Álvarez CM, Garcia-Iglesias Y, Guerrero-González JM, Romero-Cachinero C, González-Cabezuelo JM, Fernandez-Rosado FJ, Arenas-Rodríguez V, Lopez-Cintas R, Alvarez-Cubero MJ, Martinez-Gonzalez LJ. Analyzing the role of ACE2, AR, MX1 and TMPRSS2 genetic markers for COVID-19 severity. Hum Genomics. 2023 Jun 7;17(1):50. doi: 10.1186/s40246-023-00496-2.

Martínez-Diz S, Marín-Benesiu F, López-Torres G, Santiago O, Díaz-Cuéllar JF, Martín-Esteban S, Cortés-Valverde AI, Arenas-Rodríguez V, Cuenca-López S, Porras-Quesada P, Ruiz-Ruiz C, Abadía-Molina AC, Entrala-Bernal C, Martínez-González LJ, Álvarez-Cubero MJ. Relevance of TMPRSS2, CD163/CD206, and CD33 in clinical severity stratification of COVID-19. Front Immunol. 2023 Mar 8;13:1094644. doi: 10.3389/fimmu.2022.1094644

  • PATIÑO MERCAU, JUAN RODRIGO

Patiño-Mercau JR, Baliñas-Gavira C, Andrades A, Benitez-Cantos MS, Rot AE, Rodriguez MI, Álvarez-Pérez JC, Cuadros M, Medina PP. BCL7A is silenced by hypermethylation to promote acute myeloid leukemia. Biomark Res. 2023 Mar 20;11(1):32. doi: 10.1186/s40364-023-00472-x.

Andrades A, Álvarez-Pérez JC, Patiño-Mercau JR, Cuadros M, Baliñas-Gavira C, Medina PP. Recurrent splice site mutations affect key diffuse large B-cell lymphoma genes. Blood. 2022 Apr 14;139(15):2406-2410. doi: 10.1182/blood.2021011708.

  • REDRUELLO ROMERO, ANAIS

Redruello-Romero A, Benitez-Cantos MS, Lopez-Perez D, García-Rubio J, Tamayo F, Pérez-Bartivas D, Moreno-SanJuan S, Ruiz-Palmero I, Puentes-Pardo JD, Vilchez JR, López-Nevot MÁ, García F, Cano C, León J, Carazo Á. Human adipose tissue as a major reservoir of cytomegalovirus-reactive T cells. Front Immunol. 2023 Nov 20;14:1303724. doi: 10.3389/fimmu.2023.1303724.

Lopez-Perez D, Redruello-Romero A, Garcia-Rubio J, Arana C, Garcia-Escudero LA, Tamayo F, Salmeron J, Galvez J, Leon J, Carazo Á. In Obese Patients With Type 2 Diabetes, Mast Cells in Omental Adipose Tissue Decrease the Surface Expression of CD45, CD117, CD203c, and FcϵRI. Front Endocrinol (Lausanne). 2022 Mar 15;13:818388. doi: 10.3389/fendo.2022.818388.

García-Rubio J, León J, Redruello-Romero A, Pavón E, Cozar A, Tamayo F, Caba-Molina M, Salmerón J, Carazo Á. Cytometric analysis of adipose tissue reveals increments of adipocyte progenitor cells after weight loss induced by bariatric surgery. Sci Rep. 2018 Oct 12;8(1):15203. doi: 10.1038/s41598-018-33488-7.

  • ORTIZ MORAL, ELVIRA CAROLINA

Salto R, Girón MD, Ortiz-Moral C, Manzano M, Vílchez JD, Reche-Perez FJ, Bueno-Vargas P, Rueda R, Lopez-Pedrosa JM. Dietary Complex and Slow Digestive Carbohydrates Prevent Fat Deposits During Catch-Up Growth in Rats. Nutrients. 2020 Aug 25;12(9):2568. doi: 10.3390/nu12092568.

  • ANTEQUERA PARRILLA, PABLO ENEAS

Antequera-Parrilla P, Castillo-Acosta VM, Bosch-Navarrete C, Ruiz-Pérez LM, González-Pacanowska D. A nuclear orthologue of the dNTP triphosphohydrolase SAMHD1 controls dNTP homeostasis and genomic stability in Trypanosoma brucei. Front Cell Infect Microbiol. 2023 Aug 22;13:1241305. doi: 10.3389/fcimb.2023.1241305.

  • RAMOS LORENTE, SARA ESTHER

Ramos-Lorente SE, Berzal-Herranz B, Romero-López C, Berzal-Herranz A. Recruitment of the 40S ribosomal subunit by the West Nile virus 3' UTR promotes the cross-talk between the viral genomic ends for translation regulation. Virus Res. 2024 May;343:199340. doi: 10.1016/j.virusres.2024.199340.

Romero-López C, Roda-Herreros M, Berzal-Herranz B, Ramos-Lorente SE, Berzal-Herranz A. Inter- and Intramolecular RNA-RNA Interactions Modulate the Regulation of Translation Mediated by the 3' UTR in West Nile Virus. Int J Mol Sci. 2023 Mar 10;24(6):5337. doi: 10.3390/ijms24065337.

Romero-López C, Ramos-Lorente SE, Berzal-Herranz A. In Vitro Methods to Decipher the Structure of Viral RNA Genomes. Pharmaceuticals (Basel). 2021 Nov 20;14(11):1192. doi: 10.3390/ph14111192. Ramos-Lorente S, Romero-López C, Berzal-Herranz A. Information Encoded by the Flavivirus Genomes beyond the Nucleotide Sequence. Int J Mol Sci. 2021 Apr 3;22(7):3738. doi: 10.3390/ijms22073738.

  • MOLINA ZAYAS, MARIA

Molina-Zayas M, Garrido-Navas C, García-Puche JL, Barwell J, Pedrinaci S, Atienza MM, García-Linares S, de Haro-Muñoz T, Lorente JA, Serrano MJ, Poyatos-Andújar A. Identification of hereditary breast and ovarian cancer germline variants in Granada (Spain): NGS perspective. Mol Genet Genomics. 2022 May;297(3):859-871. doi: 10.1007/s00438-022-01891-5

  • JUEZ CASTILLO, GRACIELA

Juez-Castillo G, Valencia-Vidal B, Orrego LM, Cabello-Donayre M, Montosa-Hidalgo L, Pérez-Victoria JM. FiCRoN, a deep learning-based algorithm for the automatic determination of intracellular parasite burden from fluorescence microscopy images. Med Image Anal. 2024 Jan;91:103036. doi: 10.1016/j.media.2023.103036.