Producción científica del profesorado del programa
The importance of COVID-19 vaccination during lactation. Valverde-Merino MI, Gomez-Guzman M, Piquer-Martinez C, Cabezas Lopez MD, Zarzuelo MJ. Infect Dis Now. 2024 Feb;54(1):104831. doi: 10.1016/j.idnow.2023.104831.
[Analysis of the legal framework on food supplements for menopause in Spanish community pharmacies]. Rubio Rubio FI, Cabezas López MD, Valverde Merino MI, Martínez Martínez F, Zarzuelo Romero MJ. Gac Sanit. 2023 Feb 15;37:102290. doi: 10.1016/j.gaceta.2023.102290.
A 12-gene pharmacogenetic panel to prevent adverse drug reactions: an open-label, multicentre, controlled, cluster-randomised crossover implementation study. Swen JJ, van der Wouden CH, Manson LE, Abdullah-Koolmees H, Blagec K, Blagus T, Böhringer S, Cambon-Thomsen A, Cecchin E, Cheung KC, Deneer VH, Dupui M, Ingelman-Sundberg M, Jonsson S, Joefield-Roka C, Just KS, Karlsson MO, Konta L, Koopmann R, Kriek M, Lehr T, Mitropoulou C, Rial-Sebbag E, Rollinson V, Roncato R, Samwald M, Schaeffeler E, Skokou M, Schwab M, Steinberger D, Stingl JC, Tremmel R, Turner RM, van Rhenen MH, Dávila Fajardo CL, Dolžan V, Patrinos GP, Pirmohamed M, Sunder-Plassmann G, Toffoli G, Guchelaar HJ; Ubiquitous Pharmacogenomics Consortium. Lancet. 2023 Feb 4;401(10374):347-356. doi: 10.1016/S0140-6736(22)01841-4.
Genetic polymorphisms in ADRB1, ADRB2 and CYP2D6 genes and response to beta-blockers in patients with acute coronary syndrome. Castaño-Amores C, Antúnez-Rodríguez A, Pozo-Agundo A, García-Rodríguez S, Martínez-González LJ, Dávila-Fajardo CL. Biomed Pharmacother. 2023 Dec 31;169:115869. doi: 10.1016/j.biopha.2023.115869
Economic evaluation of pharmacogenomic-guided antiplatelet treatment in Spanish patients suffering from acute coronary syndrome participating in the U-PGx PREPARE study. Koufaki MI, Fragoulakis V, Díaz-Villamarín X, Karamperis K, Vozikis A, Swen JJ, Dávila-Fajardo CL, Vasileiou KZ, Patrinos GP, Mitropoulou C. Hum Genomics. 2023 Jun 7;17(1):51. doi: 10.1186/s40246-023-00495-3. Targeted next-generation sequencing panel to investigate antiplatelet adverse reactions in acute coronary syndrome patients undergoing percutaneous coronary intervention with stenting. Antúnez-Rodríguez A, García-Rodríguez S, Pozo-Agundo A, Sánchez-Ramos JG, Moreno-Escobar E, Triviño-Juárez JM, Martínez-González LJ, Dávila-Fajardo CL. Thromb Res. 2024 Aug;240:109060. doi: 10.1016/j.thromres.2024.109060.
Azathioprine dose tailoring based on pharmacogenetic information: Insights of clinical implementation. Díaz-Villamarín X, Fernández-Varón E, Rojas Romero MC, Callejas-Rubio JL, Cabeza-Barrera J, Rodríguez-Nogales A, Gálvez J, Morón R. Biomed Pharmacother. 2023 Dec;168:115706. doi: 10.1016/j.biopha.2023.115706.
Population pharmacokinetics and pharmacokinetic/pharmacodynamic evaluation of marbofloxacin against Coagulase-negative staphylococci, Staphylococcus aureus and Mycoplasma agalactiae pathogens in goats. Serrano-Rodríguez JM, Fernández-Varón E, Rodríguez CMC, Andrés-Larrea MIS, Rubio-Langre S, de la Fe C, Dova SW, Bhardwaj P, Sidhu PK, Litterio NJ, Lorenzutti AM. Res Vet Sci. 2023 Jun;159:1-10. doi: 10.1016/j.rvsc.2023.03.026.
Gut Microbiota Composition Can Predict Colonization by Multidrug-Resistant Bacteria in SARS-CoV-2 Patients in Intensive Care Unit: A Pilot Study. García-García J, Diez-Echave P, Yuste ME, Chueca N, García F, Cabeza-Barrera J, Fernández-Varón E, Gálvez J, Colmenero M, Rodríguez-Cabezas ME, Rodríguez-Nogales A, Morón R. Antibiotics (Basel). 2023 Mar 2;12(3):498. doi: 10.3390/antibiotics12030498.
Novel Genetic Variants Explaining Severe Adverse Drug Events after Clinical Implementation of DPYD Genotype-Guided Therapy with Fluoropyrimidines: An Observational Study. Díaz-Villamarín X, Martínez-Pérez M, Nieto-Sánchez MT, Ruiz-Tueros G, Fernández-Varón E, Torres-García A, González Astorga B, Blancas I, Iáñez AJ, Cabeza-Barrera J, Morón R. Pharmaceutics. 2024 Jul 19;16(7):956. doi: 10.3390/pharmaceutics16070956.
Effect of Pharmaceutical Intervention in Pharmacologically Treated Hypertensive Patients-A Cluster-Randomized Clinical Trial: AFPRES-CLM Study. Luque Del Moral R, Gastelurrutia MA, Martinez-Martinez F, Jacomé JA, Dago A, Suarez B, Fikri-Benbrahim N, Martí M, Nuñez C, Sierra-Alarcón S, Fernandez-Gomez FJ. J Pers Med. 2023 Oct 11;13(10):1484. doi: 10.3390/jpm13101484.
Antimicrobial stewardship in hospitals: Expert recommendation guidance document for activities in specific populations, syndromes and other aspects (PROA-2) from SEIMC, SEFH, SEMPSPGS, SEMICYUC and SEIP. Cercenado E, Rodríguez-Baño J, Alfonso JL, Calbo E, Escosa L, Fernández-Polo A, García-Rodríguez J, Garnacho J, Gil-Navarro MV, Grau S, Gudiol C, Horcajada JP, Larrosa N, Martínez C, Molina J, Nuvials X, Oliver A, Paño-Pardo JR, Pérez-Rodríguez MT, Ramírez P, Rey-Biel P, Vidal P, Retamar-Gentil P. Enferm Infecc Microbiol Clin (Engl Ed). 2023 Apr;41(4):238-242. doi: 10.1016/j.eimce.2022.05.013.
Model-Informed Precision Dosing Software Tools for Dosage Regimen Individualization: A Scoping Review. Del Valle-Moreno P, Suarez-Casillas P, Mejías-Trueba M, Ciudad-Gutiérrez P, Guisado-Gil AB, Gil-Navarro MV, Herrera-Hidalgo L. Pharmaceutics. 2023 Jul 1;15(7):1859. doi: 10.3390/pharmaceutics15071859.
Pharmacological interaction between rifamycins and anticoagulants: Case report. Rodríguez-de Francisco L, Luque-Márquez R, Mejías-Trueba M, Herrera-Hidalgo L, Gil-Navarro MV. Farm Hosp. 2024 Sep-Oct;48(5):259-261. doi: 10.1016/j.farma.2024.03.001.
Stability of temocillin in outpatient parenteral antimicrobial therapy: is it a real option? Fernández-Rubio B, Herrera-Hidalgo L, López-Cortés LE, Luque-Márquez R, De Alarcón A, Luque-Pardos S, Fernández-Polo A, Gutiérrez-Urbón JM, Rodríguez-Baño J, Gil-Navarro MV, Gutiérrez-Valencia A. J Antimicrob Chemother. 2023 Oct 3;78(10):2451-2456. doi: 10.1093/jac/dkad251.
Development of Antimicrobial Defined Daily Dose (DDD) for the Pediatric Population. Montecatine-Alonso E, Mejías-Trueba M, Goycochea-Valdivia WA, Chavarri-Gil E, Fernández-Llamazares CM, Dolz E, Gutiérrez-Urbón JM, Gallego-Fernández C, Llorente-Gutiérrez J, Gil-Navarro MV. Antibiotics (Basel). 2023 Jan 31;12(2):276. doi: 10.3390/antibiotics12020276.
Agreement between pharmacists and physicians on the assessment of appropriateness of antimicrobial prescribing. Gutiérrez-Urbón JM, Campelo-Sánchez E, Cobo-Sacristán S, Domínguez-Cantero M, Gil-Navarro MV, Luque S, Martínez-Núñez ME, Mejuto B, Moreno-Ramos F, Periañez-Párraga L, Rodríguez-González C, Rodríguez-Jato T; members of the Pharmaceutical Care Group for Patients with Infectious Diseases (AFinf) of the Spanish Society of Hospital Pharmacy (SEFH). Enferm Infecc Microbiol Clin (Engl Ed). 2023 Oct 31:S2529-993X(23)00253-8. doi: 10.1016/j.eimce.2023.06.008.
Antimicrobial Defined Daily Dose in Neonatal Population: Validation in the Clinical Practice. Villanueva-Bueno C, Montecatine-Alonso E, Jiménez-Parrilla F, González-López M, Manrique-Rodríguez S, Moreno-Ramos F, Cañete-Ramírez C, Dolz E, García-Robles A, Caro-Teller JM, Moral-Pumarega MT, Bergon-Sendin E, Gómez-Trevecedo Calvo MT, Gallego-Fernández C, Vayo-Benito CÁD, Mejías-Trueba M, Gil-Navarro MV, Paediatric Antimicrobial Defined Daily Dose Study Group KiDDDs. Antibiotics (Basel). 2023 Mar 17;12(3):602. doi: 10.3390/antibiotics12030602. Application of new indicators to assess the quality of antimicrobial use in intensive care units. Rodríguez-Campos E, Guisado-Gil AB, Peñalva G, Fernández-Rubio B, Aldabó T, Herrera-Hidalgo L, Fernández-Delgado E, Mejías-Trueba M, Adriaensens M, Gascón ML, Cisneros JM, Gil-Navarro MV. Int J Antimicrob Agents. 2023 Aug;62(2):106865. doi: 10.1016/j.ijantimicag.2023.106865.
Clinical and Ecological Impact of an Educational Program to Optimize Antibiotic Treatments in Nursing Homes (PROA-SENIOR): A Cluster, Randomized, Controlled Trial and Interrupted Time-Series Analysis. Peñalva G, Crespo-Rivas JC, Guisado-Gil AB, Rodríguez-Villodres Á, Pachón-Ibáñez ME, Cachero-Alba B, Rivas-Romero B, Gil-Moreno J, Galvá-Borras MI, García-Moreno M, Salamanca-Bautista MD, Martínez-Rascón MB, Cantudo-Cuenca MR, Ninahuaman-Poma RC, Enrique-Mirón MLÁ, Pérez-Barroso A, Marín-Ariza I, González-Florido M, Mora-Santiago MDR, Belda-Rustarazo S, Expósito-Tirado JA, Rosso-Fernández CM, Gil-Navarro MV, Lepe-Jiménez JA, Cisneros JM; PROA-SENIOR Study Group. Clin Infect Dis. 2023 Mar 4;76(5):824-832. doi: 10.1093/cid/ciac834.
Long-term outcomes of an educational paediatric antimicrobial stewardship programme: a quality improvement study. Aboza Garcia M, Goycochea-Valdivia W, Peñalva G, Falcon Neyra L, Moleón Ruiz M, Rodriguez-Villodres A, Montero Valladares C, Olbrich P, Sánchez-Valderrabanos E, Jiménez F, Molina M, Moreno Madueño G, Valencia Martin R, Gil Navarro MV, Molina J, Neth O, Cisneros JM. Arch Dis Child. 2024 Jan 22;109(2):144-151. doi: 10.1136/archdischild-2022-323802.
Antimicrobial Stewardship in the Emergency Department Observation Unit: Definition of a New Indicator and Evaluation of Antimicrobial Use and Clinical Outcomes. Guisado-Gil AB, Mejías-Trueba M, Peñalva G, Aguilar-Guisado M, Molina J, Gimeno A, Álvarez-Marín R, Praena J, Bueno C, Lepe JA, Gil-Navarro MV, Cisneros JM. Antibiotics (Basel). 2024 Apr 12;13(4):356. doi: 10.3390/antibiotics13040356.
Theories, models and frameworks for health systems integration. A scoping review. Piquer-Martinez C, Urionagüena A, Benrimoj SI, Calvo B, Dineen-Griffin S, Garcia-Cardenas V, Fernandez-Llimos F, Martinez-Martinez F, Gastelurrutia MA. Health Policy. 2024 Mar;141:104997. doi: 10.1016/j.healthpol.2024.104997.
Medication Review with Follow-Up for End-Stage Renal Disease: Drug-Related Problems and Negative Outcomes Associated with Medication-A Systematic Review. Pereira-Céspedes A, Jiménez-Morales A, Palomares-Bayo M, Martínez-Martínez F, Calleja-Hernández MÁ. J Clin Med. 2023 Aug 2;12(15):5080. doi: 10.3390/jcm12155080.
Community pharmacy and primary health care - Types of integration and their applicability: A narrative review. Urionagüena A, Piquer-Martinez C, Gastelurrutia MÁ, Benrimoj SI, Garcia-Cardenas V, Fernandez-Llimos F, Martinez-Martinez F, Calvo B. Res Social Adm Pharm. 2023 Mar;19(3):414-431. doi: 10.1016/j.sapharm.2022.10.007
Spanish translation of the ABC taxonomy for medication adherence. Garcia-Cardenas V, Hughes D, Aguilar-Palacio I, Benrimoj SI, Rabanaque MJ, Martinez-Martinez F, Malo S. Res Social Adm Pharm. 2023 Sep;19(9):1292-1297. doi: 10.1016/j.sapharm.2023.05.012.
Suitability of indexing terms in the MEDLINE bibliographic database on drug-related problems. Martínez-Aguilar L, Sanz-Valero J, Martínez-Martínez F, Faus MJ. Res Social Adm Pharm. 2023 Nov;19(11):1440-1445. doi: 10.1016/j.sapharm.2023.07.006.
Effect of Pharmaceutical Intervention in Pharmacologically Treated Hypertensive Patients-A Cluster-Randomized Clinical Trial: AFPRES-CLM Study. Luque Del Moral R, Gastelurrutia MA, Martinez-Martinez F, Jacomé JA, Dago A, Suarez B, Fikri-Benbrahim N, Martí M, Nuñez C, Sierra-Alarcón S, Fernandez-Gomez FJ. J Pers Med. 2023 Oct 11;13(10):1484. doi: 10.3390/jpm13101484.
Feasibility and reliability of a quality indicator system for an ambulatory dispensing service. Bautista Gómez AJ, López Orozco M, Barajas Esparza L, de La Cruz Durán H, Chehue Romero A, Bermúdez Camps IB, Téllez López AM, López Vargas LC, Valverde Merino MI, Martínez Martínez F, Reyes Hernández I. Drugs Context. 2024 May 24;13:2024-1-3. doi: 10.7573/dic.2024-1-3.
Public interest in drug-related problems reflected in information search trends: an infodemiological study. Martínez-Aguilar L, Sanz-Lorente M, Martínez-Martínez F, Faus MJ, Sanz-Valero J. Daru. 2024 Jun 18. doi: 10.1007/s40199-024-00519-w.
Health-Related Quality of Life and Associated Factors in Patients Undergoing Kidney Replacement Therapies. Pereira-Céspedes A, Jiménez-Morales A, Polo-Moyano A, Spruce-Esparza E, Palomares-Bayo M, Martínez-Martínez F, Calleja-Hernández MÁ. Farm Hosp. 2024 Sep 17:S1130-6343(24)00143-0. doi: 10.1016/j.farma.2024.08.008. Online ahead of print.
Community pharmacy & primary care integration: qualitative study on stakeholders' opinions and interventions. Urionagüena A, Piquer-Martinez C, Benrimoj SI, Calvo B, Garcia-Cardenas V, Martinez-Martinez F, Gastelurrutia MA. J Pharm Policy Pract. 2024 Sep 6;17(1):2395551. doi: 10.1080/20523211.2024.2395551.
Mapping the concept of health care integration: A lexicographic analysis of scientific literature. Urionagüena A, Piquer-Martinez C, Benrimoj SI, Calvo B, Garcia-Cardenas V, Gastelurrutia MA, Martinez-Martinez F, Fernandez-Llimos F. Res Social Adm Pharm. 2024 May;20(5):506-511. doi: 10.1016/j.sapharm.2024.01.013.
Identification of high-risk patients for referral through machine learning assisting the decision making to manage minor ailments in community pharmacies. Amador-Fernández N, Benrimoj SI, García-Cárdenas V, Gastelurrutia MÁ, Graham EL, Palomo-Llinares R, Sánchez-Tormo J, Baixauli Fernández VJ, Pérez Hoyos E, Plaza Zamora J, Colomer Molina V, Fuertes González R, García Agudo Ó, Martínez-Martínez F. Front Pharmacol. 2023 Jul 11;14:1105434. doi: 10.3389/fphar.2023.1105434.
Factors Contributing to Negative Outcomes Associated with Medications and Drug-Related Problems in Kidney Replacement Therapy-A Hospital-Based Prospective Observational Study. Pereira-Céspedes A, Jiménez-Morales A, Polo-Moyano A, Palomares-Bayo M, Martínez-Martínez F, Calleja-Hernández MÁ. J Clin Med. 2024 Feb 12;13(4):1048. doi: 10.3390/jcm13041048.
Efficient removal of triclosan from water through activated carbon adsorption and photodegradation processes. Medellín-Castillo NA, González-Fernández LA, Ocampo-Pérez R, Leyva-Ramos R, Luiz-Dotto G, Flores-Ramírez R, Navarro-Frómeta AE, Aguilera-Flores MM, Carrasco-Marín F, Hernández-Mendoza H, Aguirre-Contreras S, Sánchez-Polo M, Ocaña-Peinado FM. Environ Res. 2024 Apr 1;246:118162. doi: 10.1016/j.envres.2024.118162.
Influence of different surgical techniques on primary implant stability in the posterior maxilla: a randomized controlled clinical trial. Olmedo-Gaya MV, Romero-Olid MN, Ocaña-Peinado FM, Vallecillo-Rivas M, Vallecillo C, Reyes-Botella C. Clin Oral Investig. 2023 Jul;27(7):3499-3508. doi: 10.1007/s00784-023-04962-y.
Knowledge, attitude, and practices of restaurant and foodservice personnel in food allergy. A systematic review and meta-analysis. Figueroa-Gómez XA, Oliveras-López MJ, Poyanco-Bugueño MF, Ocaña-Peinado FM, López-García de la Serrana H, Araya Quezada M. Heliyon. 2024 Jun 24;10(13):e33431. doi: 10.1016/j.heliyon.2024.e33431.
Challenges for Economic Evaluations of Advanced Therapy Medicinal Products: A Systematic Review. Olry de Labry-Lima A, Ponce-Polo A, García-Mochón L, Ortega-Ortega M, Pérez-Troncoso D, Epstein D. Value Health. 2023 Jan;26(1):138-150. doi: 10.1016/j.jval.2022.07.004.
Economic evaluation of adjuvant therapy with osimertinib in patients with early-stage non-small cell lung cancer and mutated EGFR. Vila Pérez A, Alegre-Del Rey EJ, Fénix-Caballero S, Špacírová Z, Rosado Varela P, Olry de Labry Lima A. Support Care Cancer. 2023 Dec 27;32(1):67. doi: 10.1007/s00520-023-08239-8.
Scoping review of the methodology of large health surveys conducted in Spain early on in the COVID-19 pandemic. Sánchez-Cantalejo Garrido C, Yucumá Conde D, Rueda MDM, Olry-de-Labry-Lima A, Martín-Ruiz E, Higueras-Callejón C, Cabrera-León A. Front Public Health. 2023 Aug 2;11:1217519. doi: 10.3389/fpubh.2023.1217519
Value of concerted and hospital hemodialysis through a multi-criteria decision analysis. Caro Martínez A, Valcárcel Cabrera MDC, Olry de Labry Lima A. Nefrologia (Engl Ed). 2023 Nov-Dec;43(6):742-749. doi: 10.1016/j.nefroe.2024.01.001.
An Umbrella Review of Cognitive Behavioural and Dialectical Behavioural Therapies to Treat Self-Harm and Suicidal Behaviour in Adolescents. Torralba-Suarez C, Olry-de-Labry-Lima A. Actas Esp Psiquiatr. 2024 Aug;52(4):549-560. doi: 10.62641/aep.v52i4.1631.
Economic assessment of abemaciclib for the adjuvant treatment of luminal HER2- breast cancer from the perspective of the Spanish health system. Fenix-Caballero S, Sanchez-Vegas A, Alegre Del-Rey EJ, Epstein D, Garcia-Mochon L, Olry de Labry Lima A. Eur J Health Econ. 2024 Apr 22. doi: 10.1007/s10198-024-01681-3.
Gender-based differences in gamification and mobile learning. Piquer-Martinez C, Valverde-Merino MI, Gomez-Guzman M, Zarzuelo MJ. Acta Physiol (Oxf). 2024 Sep;240(9):e14206. doi: 10.1111/apha.14206
Community pharmacy is the key to improving vitamin D levels. Lopez-Carmona F, Toro-Ruiz A, Gomez-Guzman M, Valverde-Merino MI, Piquer-Martinez C, Zarzuelo MJ. Explor Res Clin Soc Pharm. 2023 Jan 18;9:100224. doi: 10.1016/j.rcsop.2023.100224
Beneficial Effects of Bovine Milk Exosomes in Metabolic Interorgan Cross-Talk. García-Martínez J, Pérez-Castillo ÍM, Salto R, López-Pedrosa JM, Rueda R, Girón MD. Nutrients. 2022 Mar 30;14(7):1442. doi: 10.3390/nu14071442.
Arginine and Lysine Supplementation Potentiates the Beneficial β-Hydroxy ß-Methyl Butyrate (HMB) Effects on Skeletal Muscle in a Rat Model of Diabetes. Manzano M, Girón MD, Salto R, Burgio C, Reinoso A, Cabrera E, Rueda R, López-Pedrosa JM. Nutrients. 2023 Nov 7;15(22):4706. doi: 10.3390/nu15224706.
Photosensitizing properties and subcellular localisation of 3,4-dihydro-β-carbolines harmaline and harmalol. Denofrio MP, Paredes JM, Yañuk JG, Giron MD, Salto R, Talavera EM, Crovetto L, Cabrerizo FM. Photochem Photobiol Sci. 2023 Mar;22(3):487-501. doi: 10.1007/s43630-022-00328-7.
Sodium Tungstate Promotes Neurite Outgrowth and Confers Neuroprotection in Neuro2a and SH-SY5Y Cells. Montero-Martin N, Girón MD, Vílchez JD, Salto R. Int J Mol Sci. 2024 Aug 23;25(17):9150. doi: 10.3390/ijms25179150.
Advanced Imaging Methodology in Bacterial Biofilms with a Fluorescent Enzymatic Sensor for pepN Activity. Valverde-Pozo J, Paredes JM, García-Rubiño ME, Girón MD, Salto R, Alvarez-Pez JM, Talavera EM. Biosensors (Basel). 2024 Sep 3;14(9):424. doi: 10.3390/bios14090424
Anisakiasis and Anisakidae. Adroher FJ, Morales-Yuste M, Benítez R. Pathogens. 2024 Feb 6;13(2):148. doi: 10.3390/pathogens13020148.
Anisakis infection in anchovies (Engraulis encrasicolus) from Iberian waters, southwestern Europe: Post-mortem larval migration. Domingo-Hernández AM, Morales-Yuste M, Buzo-Domínguez S, Adroher FJ, Benítez R. Res Vet Sci. 2023 Apr;157:26-34. doi: 10.1016/j.rvsc.2023.02.007.
Bayesian interpretation of immunotherapy trials with dynamic treatment effects. Castañon E, Sanchez-Arraez Á, Jimenez-Fonseca P, Alvarez-Manceñido F, Martínez-Martínez I, Mihic Gongora L, Carmona-Bayonas A. Eur J Cancer. 2022 Jan;161:79-89. doi: 10.1016/j.ejca.2021.11.002.
Is there a preferred platinum and fluoropyrimidine regimen for advanced HER2-negative esophagogastric adenocarcinoma? Insights from 1293 patients in AGAMENON-SEOM registry. Arias-Martinez A, Martínez de Castro E, Gallego J, Arrazubi V, Custodio A, Fernández Montes A, Diez M, Hernandez R, Limón ML, Cano JM, Vidal-Tocino R, Macias I, Visa L, Martin Richard M, Sauri T, Hierro C, Gil M, Cerda P, Martínez Moreno E, Martínez Lago N, Mérida-García AJ, Gómez González L, García Navalón FJ, Ruiz Martín M, Marín G, López-López F, Ruperez Blanco AB, Fernández AF, Jimenez-Fonseca P, Carmona-Bayonas A, Alvarez-Manceñido F. Clin Transl Oncol. 2024 Jul;26(7):1674-1686. doi: 10.1007/s12094-024-03388-6.
Onychocolone A produced by the fungus Onychocola sp. targets cancer stem cells and stops pancreatic cancer progression by inhibiting MEK2-dependent cell signaling. Ramos MC, Crespo-Sueiro G, de Pedro N, Griñán-Lisón C, Díaz C, Pérez-Victoria I, González-Menéndez V, Castillo F, Pérez Del Palacio J, Tormo JR, Choquesillo-Lazarte D, Marchal JA, Vicente F, Fernández-Godino R, Genilloud O, Reyes F. Biomed Pharmacother. 2024 Aug;177:117018. doi: 10.1016/j.biopha.2024.117018.
Establishment of a screening platform based on human coronavirus OC43 for the identification of microbial natural products with antiviral activity. Martínez-Arribas B, Annang F, Díaz-González R, Pérez-Moreno G, Martín J, Mackenzie TA, Castillo F, Reyes F, Genilloud O, Ruiz-Pérez LM, Vicente F, Ramos MC, González-Pacanowska D. Microbiol Spectr. 2024 Jan 11;12(1):e0167923. doi: 10.1128/spectrum.01679-23.
Discovery of bioactive natural products of microbial origin as inhibitors of the PD-1/PD-L1 protein-protein interaction. Domingo-Contreras E, Tormo JR, Gonzalez-Menendez V, Mackenzie TA, Martín-Serrano J, Magiera-Mularz K, Kitel R, Reyes F, Genilloud O, Fernández-Godino R, Ramos MC, Castillo F. Int J Biol Macromol. 2024 Apr;264(Pt 1):130458. doi: 10.1016/j.ijbiomac.2024.130458.
Repurposing the Open Global Health Library for the discovery of novel Mpro destabilizers with scope as broad-spectrum antivirals. Castillo F, Ramírez D, Ramos MC, Martinez-Arribas B, Domingo-Contreras E, Mackenzie TA, Peña-Varas C, Lindemann S, Montero F, Annang F, Vicente F, Genilloud O, González-Pacanowska D, Fernandez-Godino R. Front Pharmacol. 2024 Jul 10;15:1390705. doi: 10.3389/fphar.2024.1390705.
A perspective current and past modes of inhalation therapy. Canto Mangana J, Schilder KA, Bretones-Pedrinaci JI, Blesa ARM, de Medina FS, Martínez-Augustin O, Daddaoua A. Microb Biotechnol. 2024 Feb;17(2):e14419. doi: 10.1111/1751-7915.14419.
Prebiotics and Probiotics: Healthy Biotools for Molecular Integrative and Modulation Approaches. Aguilera M, Daddaoua A. Int J Mol Sci. 2023 Apr 20;24(8):7559. doi: 10.3390/ijms24087559.
Prebiotics and Probiotics: Healthy Biotools for Molecular Integrative and Modulation Approaches 2.0. Aguilera M, Daddaoua A. Int J Mol Sci. 2024 Apr 30;25(9):4872. doi: 10.3390/ijms25094872.
Rio Tinto as a niche for acidophilus enzymes of industrial relevance. Daddaoua A, Álvarez C, Oggerin M, Rodriguez N, Duque E, Amils R, Armengaud J, Segura A, Ramos JL. Microb Biotechnol. 2023 May;16(5):1069-1086. doi: 10.1111/1751-7915.14192. 5 Characterization of an extremophile bacterial acid phosphatase derived from metagenomics analysis. Recio MI, de la Torre J, Daddaoua A, Udaondo Z, Duque E, Gavira JA, López-Sánchez C, Ramos JL. Microb Biotechnol. 2024 Apr;17(4):e14404. doi: 10.1111/1751-7915.14404.
Metabolomics signature as a survival predictor in patients with resectable colorectal liver metastasis. González-Olmedo C, García-Verdejo FJ, Reguera-Teba A, Rosa-Garrido C, López-López JA, Díaz-Beltrán L, García PM, Luque-Caro N, Gálvez-Montosa F, Ortega-Granados AL, Ruiz-Sanjuan M, Cózar-Ibáñez A, Sainz J, Marchal JA, Camacho J, Del Palacio JP, Fernández-Godino R, Díaz C, Sánchez-Rovira P. Clin Transl Med. 2024 Jan;14(1):e1541. doi: 10.1002/ctm2.1541.
Preclinical Evaluation of an Imidazole-Linked Heterocycle for Alzheimer's Disease. Bagán A, Rodriguez-Arévalo S, Taboada-Jara T, Griñán-Ferré C, Pallàs M, Brocos-Mosquera I, Callado LF, Morales-García JA, Pérez B, Diaz C, Fernández-Godino R, Genilloud O, Beljkas M, Oljacic S, Nikolic K, Escolano C. Pharmaceutics. 2023 Sep 25;15(10):2381. doi: 10.3390/pharmaceutics15102381.
Complement factor B is critical for sub-RPE deposit accumulation in a model of Doyne honeycomb retinal dystrophy with features of age-related macular degeneration. Crowley MA, Garland DL, Sellner H, Banks A, Fan L, Rejtar T, Buchanan N, Delgado O, Xu YY, Jose S, Adams CM, Mogi M, Wang K, Bigelow CE, Poor S, Anderson K, Jaffee BD, Prasanna G, Grosskreutz C, Fernandez-Godino R, Pierce EA, Dryja TP, Liao SM. Hum Mol Genet. 2023 Jan 6;32(2):204-217. doi: 10.1093/hmg/ddac187..
Discovery of bioactive natural products of microbial origin as inhibitors of the PD-1/PD-L1 protein-protein interaction. Domingo-Contreras E, Tormo JR, Gonzalez-Menendez V, Mackenzie TA, Martín-Serrano J, Magiera-Mularz K, Kitel R, Reyes F, Genilloud O, Fernández-Godino R, Ramos MC, Castillo F. Int J Biol Macromol. 2024 Apr;264(Pt 1):130458. doi: 10.1016/j.ijbiomac.2024.130458
Onychocolone A produced by the fungus Onychocola sp. targets cancer stem cells and stops pancreatic cancer progression by inhibiting MEK2-dependent cell signaling. Ramos MC, Crespo-Sueiro G, de Pedro N, Griñán-Lisón C, Díaz C, Pérez-Victoria I, González-Menéndez V, Castillo F, Pérez Del Palacio J, Tormo JR, Choquesillo-Lazarte D, Marchal JA, Vicente F, Fernández-Godino R, Genilloud O, Reyes F. Biomed Pharmacother. 2024 Aug;177:117018. doi: 10.1016/j.biopha.2024.117018.
Dual targeting of the class V lanthipeptide antibiotic cacaoidin. Deisinger JP, Arts M, Kotsogianni I, Puls JS, Grein F, Ortiz-López FJ, Martin NI, Müller A, Genilloud O, Schneider T. iScience. 2023 Mar 11;26(4):106394. doi: 10.1016/j.isci.2023.106394.
Antiparasitic Meroterpenoids Isolated from Memnoniella dichroa CF-080171. Annang FB, Pérez-Moreno G, Bosch-Navarrete C, González-Menéndez V, Martín J, Mackenzie TA, Ramos MC, Ruiz-Pérez LM, Genilloud O, González-Pacanowska D, Vicente F, Reyes F. Pharmaceutics. 2023 Feb 2;15(2):492. doi: 10.3390/pharmaceutics15020492
Crossiellidines A-F, Unprecedented Pyrazine-Alkylguanidine Metabolites with Broad-Spectrum Antibacterial Activity from Crossiella sp. Ortiz-López FJ, Oves-Costales D, Carretero-Molina D, Martín J, Díaz C, de la Cruz M, Román-Hurtado F, Álvarez-Arévalo M, Jørgensen TS, Reyes F, Weber T, Genilloud O. Org Lett. 2023 May 19;25(19):3502-3507. doi: 10.1021/acs.orglett.3c01088.
Identification and heterologous expression of the globomycin biosynthetic gene cluster. Oves-Costales D, Gren T, Sterndorff EB, Martín J, Ortiz-López FJ, Jørgensen TS, Jiang X, Román-Hurtado F, Reyes F, Genilloud O, Weber T. Synth Syst Biotechnol. 2023 Feb 7;8(2):206-212. doi: 10.1016/j.synbio.2023.02.001.
Escuzarmycins A-D, Potent Biofungicides to Control Septoria tritici Blotch. Fernández-Pastor I, González-Menéndez V, González I, Serrano R, Mackenzie TA, Benítez G, Casares-Porcel M, Genilloud O, Reyes F. J Agric Food Chem. 2024 Jul 10;72(27):15256-15264. doi: 10.1021/acs.jafc.4c01303.
Complete Genome Sequence Analysis of Kribbella sp. CA-293567 and Identification of the Kribbellichelins A & B and Sandramycin Biosynthetic Gene Clusters. Sánchez-Hidalgo M, García MJ, González I, Oves-Costales D, Genilloud O. Microorganisms. 2023 Jan 19;11(2):265. doi: 10.3390/microorganisms11020265.
Strasseriolides display in vitro and in vivo activity against trypanosomal parasites and cause morphological and size defects in Trypanosoma cruzi. Bosch-Navarrete C, Pérez-Moreno G, Annang F, Diaz-Gonzalez R, García-Hernández R, Rocha H, Gamarro F, Cordón-Obras C, Navarro M, Rodriguez A, Genilloud O, Reyes F, Vicente F, Ruiz-Pérez LM, González-Pacanowska D. PLoS Negl Trop Dis. 2023 Sep 15;17(9):e0011592. doi: 10.1371/journal.pntd.0011592.
New Phocoenamicin and Maklamicin Analogues from Cultures of Three Marine-Derived Micromonospora Strains. Kokkini M, Oves-Costales D, Sánchez P, Melguizo Á, Mackenzie TA, Pérez-Bonilla M, Martín J, Giusti A, de Witte P, Vicente F, Genilloud O, Reyes F. Mar Drugs. 2023 Aug 7;21(8):443. doi: 10.3390/md21080443.
Development and Validation of a HTS Platform for the Discovery of New Antifungal Agents against Four Relevant Fungal Phytopathogens. Serrano R, González-Menéndez V, Tormo JR, Genilloud O. J Fungi (Basel). 2023 Aug 28;9(9):883. doi: 10.3390/jof9090883.
Interactions of Different Streptomyces Species and Myxococcus xanthus Affect Myxococcus Development and Induce the Production of DK-Xanthenes. Santamaría RI, Martínez-Carrasco A, Tormo JR, Martín J, Genilloud O, Reyes F, Díaz M. Int J Mol Sci. 2023 Oct 27;24(21):15659. doi: 10.3390/ijms242115659.
Genome-Led Discovery of the Antibacterial Cyclic Lipopeptide Kutzneridine A and Its Silent Biosynthetic Gene Cluster from Kutzneria Species. Ortiz-López FJ, Oves-Costales D, Guerrero Garzón JF, Gren T, Baggesgaard Sterndorff E, Jiang X, Sparholt Jo Rgensen T, Blin K, Fernández-Pastor I, Tormo JR, Martín J, Sánchez P, Moreno MC, Reyes F, Genilloud O, Weber T. J Nat Prod. 2024 Sep 27. doi: 10.1021/acs.jnatprod.4c00633.
Establishment of a screening platform based on human coronavirus OC43 for the identification of microbial natural products with antiviral activity. Martínez-Arribas B, Annang F, Díaz-González R, Pérez-Moreno G, Martín J, Mackenzie TA, Castillo F, Reyes F, Genilloud O, Ruiz-Pérez LM, Vicente F, Ramos MC, González-Pacanowska D. Microbiol Spectr. 2024 Jan 11;12(1):e0167923. doi: 10.1128/spectrum.01679-23.
Xerophytic Lichens from Gypsiferous Outcrops of Arid Areas of Andalusia as a Source of Anti-Phytopathogenic Depsides. Fernández-Pastor I, González-Menéndez V, Martínez Andrade K, Serrano R, Mackenzie TA, Benítez G, Casares-Porcel M, Genilloud O, Reyes F. J Fungi (Basel). 2023 Aug 30;9(9):887. doi: 10.3390/jof9090887.
Discovery of bioactive natural products of microbial origin as inhibitors of the PD-1/PD-L1 protein-protein interaction. Domingo-Contreras E, Tormo JR, Gonzalez-Menendez V, Mackenzie TA, Martín-Serrano J, Magiera-Mularz K, Kitel R, Reyes F, Genilloud O, Fernández-Godino R, Ramos MC, Castillo F. Int J Biol Macromol. 2024 Apr;264(Pt 1):130458. doi: 10.1016/j.ijbiomac.2024.130458
Identification of novel small molecule-based strategies of COL7A1 upregulation and readthrough activity for the treatment of recessive dystrophic epidermolysis bullosa. Jover I, Ramos MC, Escámez MJ, Lozoya E, Tormo JR, de Prado-Verdún D, Mencía Á, Pont M, Puig C, Larraufie MH, Gutiérrez-Caballero C, Reyes F, Trincado JL, García-González V, Cerrato R, Andrés M, Crespo M, Vicente F, Godessart N, Genilloud O, Larcher F, Nueda A. Sci Rep. 2024 Aug 16;14(1):18969. doi: 10.1038/s41598-024-67398-8.
Naphthoquinone Derivatives from Angustimassarina populi CF-097565 Display Anti-Tumour Activity in 3D Cultures of Breast Cancer Cells. Mackenzie TA, Reyes F, Martínez M, González-Menéndez V, Sánchez I, Genilloud O, Tormo JR, Ramos MC. Molecules. 2024 Jan 15;29(2):425. doi: 10.3390/molecules29020425.
Evaluation of pro-regenerative and anti-inflammatory effects of isolecanoric acid in the muscle: Potential treatment of Duchenne Muscular Dystrophy. Matias-Valiente L, Sanchez-Fernandez C, Rodriguez-Outeiriño L, Ramos MC, Díaz C, Crespo G, González-Menéndez V, Genilloud O, Reyes F, Montolio M, Hernandez-Torres F, Aranega AE. Biomed Pharmacother. 2024 Jan;170:116056. doi: 10.1016/j.biopha.2023.116056.
Onychocolone A produced by the fungus Onychocola sp. targets cancer stem cells and stops pancreatic cancer progression by inhibiting MEK2-dependent cell signaling. Ramos MC, Crespo-Sueiro G, de Pedro N, Griñán-Lisón C, Díaz C, Pérez-Victoria I, González-Menéndez V, Castillo F, Pérez Del Palacio J, Tormo JR, Choquesillo-Lazarte D, Marchal JA, Vicente F, Fernández-Godino R, Genilloud O, Reyes F. Biomed Pharmacother. 2024 Aug;177:117018. doi: 10.1016/j.biopha.2024.117018.
Treatment of Chronic Lymphocytic Leukemia in the Personalized Medicine Era. Sánchez Suárez MDM, Martín Roldán A, Alarcón-Payer C, Rodríguez-Gil MÁ, Poquet-Jornet JE, Puerta Puerta JM, Jiménez Morales A. Pharmaceutics. 2023 Dec 29;16(1):55. doi: 10.3390/pharmaceutics16010055.
Medication Review with Follow-Up for End-Stage Renal Disease: Drug-Related Problems and Negative Outcomes Associated with Medication-A Systematic Review. Pereira-Céspedes A, Jiménez-Morales A, Palomares-Bayo M, Martínez-Martínez F, Calleja-Hernández MÁ. J Clin Med. 2023 Aug 2;12(15):5080. doi: 10.3390/jcm12155080.
A Real-World Evidence-Based Study of Long-Term Tyrosine Kinase Inhibitors Dose Reduction or Discontinuation in Patients with Chronic Myeloid Leukaemia. Martín Roldán A, Sánchez Suárez MDM, Alarcón-Payer C, Jiménez Morales A, Puerta Puerta JM. Pharmaceutics. 2023 Apr 28;15(5):1363. doi: 10.3390/pharmaceutics15051363
The Antimicrobial Activity of Micron-Thin Sol-Gel Films Loaded with Linezolid and Cefoxitin for Local Prevention of Orthopedic Prosthesis-Related Infections. Toirac B, Aguilera-Correa JJ, Mediero A, Esteban J, Jiménez-Morales A. Gels. 2023 Feb 23;9(3):176. doi: 10.3390/gels9030176.
Polymorphisms in VDR, CYP27B1, CYP2R1, GC and CYP24A1 Genes as Biomarkers of Survival in Non-Small Cell Lung Cancer: A Systematic Review. Pineda-Lancheros LE, Gálvez-Navas JM, Rojo-Tolosa S, Membrive-Jiménez C, Valverde-Merino MI, Martínez-Martínez F, Sánchez-Martín A, Ramírez-Tortosa M, Pérez-Ramírez C, Jiménez-Morales A. Nutrients. 2023 Mar 21;15(6):1525. doi: 10.3390/nu15061525.
Pharmaceutical recommendations for therapeutic appropriateness in multiple sclerosis patients. Sánchez Suárez MDM, Martín Roldán A, Cantudo Cuenca MR, Jiménez Morales A. Farm Hosp. 2024 Sep-Oct;48(5):230-233. doi: 10.1016/j.farma.2024.02.015. Epub 2024 Mar 27.
Single Nucleotide Polymorphisms in the Vitamin D Metabolic Pathway and Their Relationship with High Blood Pressure Risk. Rojo-Tolosa S, Márquez-Pete N, Gálvez-Navas JM, Pineda-Lancheros LE, Fernández-Alonso A, Membrive-Jiménez C, Ramírez-Tortosa MC, Pérez-Ramírez C, Jiménez-Morales A. Int J Mol Sci. 2023 Mar 22;24(6):5974. doi: 10.3390/ijms24065974.
Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype. Rojo-Tolosa S, Sánchez-Martínez JA, Pineda-Lancheros LE, Gálvez-Navas JM, González-Gutiérrez MV, Jiménez-Gálvez G, Pérez-Ramírez C, Morales-García C, Jiménez-Morales A. Int J Mol Sci. 2023 Apr 10;24(8):7029. doi: 10.3390/ijms24087029.
Impact of Omalizumab in Patients with Severe Uncontrolled Asthma and Possible Predictive Biomarkers of Response: A Real-Life Study. Rojo-Tolosa S, González-Gutiérrez MV, Sánchez-Martínez JA, Jiménez-Gálvez G, Pineda-Lancheros LE, Gálvez-Navas JM, Jiménez-Morales A, Pérez-Ramírez C, Morales-García C. Pharmaceutics. 2023 Feb 4;15(2):523. doi: 10.3390/pharmaceutics15020523.
Association of Single-Nucleotide Polymorphisms in Capecitabine Bioactivation Pathway with Adjuvant Therapy Safety in Colorectal Cancer Patients. Cura Y, Sánchez-Martín A, Márquez-Pete N, González-Flores E, Martínez-Martínez F, Pérez-Ramírez C, Jiménez-Morales A. Pharmaceutics. 2023 Oct 28;15(11):2548. doi: 10.3390/pharmaceutics15112548.
Impact of Anti-IL5 Therapies on Patients with Severe Uncontrolled Asthma and Possible Predictive Biomarkers of Response: A Real-Life Study. Rojo-Tolosa S, González-Gutiérrez MV, Jiménez-Gálvez G, Sánchez-Martínez JA, Pineda-Lancheros LE, Gálvez-Navas JM, Jiménez-Morales A, Pérez-Ramírez C, Morales-García C. Int J Mol Sci. 2023 Jan 19;24(3):2011. doi: 10.3390/ijms24032011.
Design of Sustainable Aluminium-Based Feedstocks for Composite Extrusion Modelling (CEM). Aguilar-García JL, Lorenzo ET, Jimenez-Morales A, Ruíz-Navas EM. Materials (Basel). 2024 Feb 27;17(5):1093. doi: 10.3390/ma17051093.
Role of Single-Nucleotide Polymorphisms in Genes Implicated in Capecitabine Pharmacodynamics on the Effectiveness of Adjuvant Therapy in Colorectal Cancer. Cura Y, Sánchez-Martín A, Márquez-Pete N, González-Flores E, Martínez-Martínez F, Pérez-Ramírez C, Jiménez-Morales A. Int J Mol Sci. 2023 Dec 20;25(1):104. doi: 10.3390/ijms25010104.
Impact of Functional Polymorphisms on Drug Survival of Biological Therapies in Patients with Moderate-to-Severe Psoriasis. Membrive-Jiménez C, Pérez-Ramírez C, Arias-Santiago S, Richetta AG, Ottini L, Pineda-Lancheros LE, Ramírez-Tortosa MDC, Jiménez-Morales A. Int J Mol Sci. 2023 May 12;24(10):8703. doi: 10.3390/ijms24108703.
Single Nucleotide Polymorphisms in the Vitamin D Metabolic Pathway as Survival Biomarkers in Colorectal Cancer. Pérez-Durán C, Márquez-Pete N, Gálvez-Navas JM, Cura Y, Rojo-Tolosa S, Pineda-Lancheros LE, Ramírez-Tortosa M, García-Collado C, Maldonado-Montoro MDM, Villar-Del-Moral JM, Pérez-Ramírez C, Jiménez-Morales A. Cancers (Basel). 2023 Aug 12;15(16):4077. doi: 10.3390/cancers15164077.
SingleNucleotide Polymorphisms as Biomarkers of Mepolizumab and Benralizumab Treatment Response in Severe Eosinophilic Asthma. Rojo-Tolosa S, Sánchez-Martínez JA, Caballero-Vázquez A, Pineda-Lancheros LE, González-Gutiérrez MV, Pérez-Ramírez C, Jiménez-Morales A, Morales-García C. Int J Mol Sci. 2024 Jul 26;25(15):8139. doi: 10.3390/ijms25158139.
Association between Single Nucleotide Polymorphisms Related to Vitamin D Metabolism and the Risk of Developing Asthma. Rojo-Tolosa S, Pineda-Lancheros LE, Gálvez-Navas JM, Sánchez-Martínez JA, González-Gutiérrez MV, Fernández-Alonso A, Morales-García C, Jiménez-Morales A, Pérez-Ramírez C. Nutrients. 2023 Feb 5;15(4):823. doi: 10.3390/nu15040823.
Dermatological toxicity associated with the use of gilteritinib in relapsed acute myeloid leukemia with FLT3 mutation: a case report. Martín Roldán A, Alarcón-Payer C, Sánchez Suárez MDM, Jiménez Morales A. Anticancer Drugs. 2024 Oct 1;35(9):872-874. doi: 10.1097/CAD.0000000000001634.
Health-Related Quality of Life and Associated Factors in Patients Undergoing Kidney Replacement Therapies. Pereira-Céspedes A, Jiménez-Morales A, Polo-Moyano A, Spruce-Esparza E, Palomares-Bayo M, Martínez-Martínez F, Calleja-Hernández MÁ. Farm Hosp. 2024 Sep 17:S1130-6343(24)00143-0. doi: 10.1016/j.farma.2024.08.008. Online ahead of print.
Precision Medicine in Childhood Cancer: The Influence of Genetic Polymorphisms on Vincristine-Induced Peripheral Neuropathy. Marangoni-Iglecias L, Rojo-Tolosa S, Márquez-Pete N, Cura Y, Moreno-Toro N, Membrive-Jiménez C, Sánchez-Martin A, Pérez-Ramírez C, Jiménez-Morales A. Int J Mol Sci. 2024 Aug 13;25(16):8797. doi: 10.3390/ijms25168797.
ABCC1, ABCG2 and FOXP3: Predictive Biomarkers of Toxicity from Methotrexate Treatment in Patients Diagnosed with Moderate-to-Severe Psoriasis. Membrive-Jiménez C, Vieira-Maroun S, Márquez-Pete N, Cura Y, Pérez-Ramírez C, Tercedor-Sánchez J, Jiménez-Morales A, Ramírez-Tortosa MDC. Biomedicines. 2023 Sep 19;11(9):2567. doi: 10.3390/biomedicines11092567.
Factors Contributing to Negative Outcomes Associated with Medications and Drug-Related Problems in Kidney Replacement Therapy-A Hospital-Based Prospective Observational Study. Pereira-Céspedes A, Jiménez-Morales A, Polo-Moyano A, Palomares-Bayo M, Martínez-Martínez F, Calleja-Hernández MÁ. J Clin Med. 2024 Feb 12;13(4):1048. doi: 10.3390/jcm13041048.
The molecular basis of cell memory in mammals: The epigenetic cycle. Espinosa-Martínez M, Alcázar-Fabra M, Landeira D. Sci Adv. 2024 Mar;10(9):eadl3188. doi: 10.1126/sciadv.adl3188. Epub 2024 Feb 28.
Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells. Asenjo HG, Alcazar-Fabra M, Espinosa-Martínez M, Lopez-Onieva L, Gallardo A, Dimitrova E, Feldmann A, Pachano T, Martorell-Marugán J, Carmona-Sáez P, Sanchez-Pozo A, Rada-Iglesias Á, Klose RJ, Landeira D. Nat Commun. 2023 Jan 12;14(1):180. doi: 10.1038/s41467-023-35859-9.
The pediatric leukemia oncoprotein NUP98-KDM5A induces genomic instability that may facilitate malignant transformation. Domingo-Reinés J, Montes R, Garcia-Moreno A, Gallardo A, Sanchez-Manas JM, Ellson I, Lamolda M, Calabro C, López-Escamez JA, Catalina P, Carmona-Sáez P, Real PJ, Landeira D, Ramos-Mejia V. Cell Death Dis. 2023 Jun 10;14(6):357. doi: 10.1038/s41419-023-05870-5.
EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells. Gallardo A, López-Onieva L, Belmonte-Reche E, Fernández-Rengel I, Serrano-Prados A, Molina A, Sánchez-Pozo A, Landeira D. Cell Death Dis. 2024 Aug 22;15(8):609. doi: 10.1038/s41419-024-07011-y.
DNA G-quadruplexes in the genome of Trypanosoma cruzi as potential therapeutic targets for Chagas disease: Dithienylethene ligands as effective antiparasitic agents. Pérez-Soto M, Ramos-Soriano J, Peñalver P, Belmonte-Reche E, O'Hagan MP, Cucchiarini A, Mergny JL, Galán MC, López López MC, Thomas MDC, Morales JC. Eur J Med Chem. 2024 Oct 5;276:116641. doi: 10.1016/j.ejmech.2024.116641.
Wild rabbits are Leishmania infantum reservoirs in southeastern Spain. Martín-Sánchez J, Díaz-Sáez V, Morillas-Márquez F, Corpas-López V, Ibáñez-De Haro P, Torres-Llamas A, Morales-Yuste M. Zoonoses Public Health. 2024 Aug;71(5):584-590. doi: 10.1111/zph.13139.
Analysis of HLA Alleles in Different Cohorts of Patients Infected by L. infantum from Southern Spain. Gutiérrez-Bautista JF, Sampedro A, Ballesta-Alcaraz L, Aguilera-Franco M, Olivares-Durán MJ, Cobo F, Reguera JA, Rodríguez-Granger J, Torres-Llamas A, Martín-Sánchez J, Aznar-Peralta I, Vilchez JR, López-Nevot MÁ, Sampedro-Martínez A. Int J Mol Sci. 2024 Jul 27;25(15):8205. doi: 10.3390/ijms25158205.
Morphology does not allow differentiating the species of the Phlebotomus perniciosus complex: Molecular characterization and investigation of their natural infection by Leishmania infantum in Morocco. Gijón-Robles P, Gómez-Mateos M, Corpas-López E, Abattouy N, Merino-Espinosa G, Morillas-Márquez F, Corpas-López V, Díaz-Sáez V, Riyad M, Martín-Sánchez J. Zoonoses Public Health. 2023 Sep;70(6):555-567. doi: 10.1111/zph.13065.
Autologous patient-derived exhausted nano T-cells exploit tumor immune evasion to engage an effective cancer therapy. Blaya-Cánovas JL, Griñán-Lisón C, Blancas I, Marchal JA, Ramírez-Tortosa C, López-Tejada A, Benabdellah K, Cortijo-Gutiérrez M, Cano-Cortés MV, Graván P, Navarro-Marchal SA, Gómez-Morales J, Delgado-Almenta V, Calahorra J, Agudo-Lera M, Sagarzazu A, Rodríguez-González CJ, Gallart-Aragón T, Eich C, Sánchez-Martín RM, Granados-Principal S. Mol Cancer. 2024 May 9;23(1):83. doi: 10.1186/s12943-024-01997-x.
Dietary antioxidants and lifespan: Relevance of environmental conditions, diet, and genotype of experimental models. Varela-López A, Romero-Márquez JM, Navarro-Hortal MD, Ramirez-Tortosa CL, Battino M, Forbes-Hernández TY, Quiles JL. Exp Gerontol. 2023 Jul;178:112221. doi: 10.1016/j.exger.2023.112221
Estradiol and Estrone Have Different Biological Functions to Induce NF-κB-Driven Inflammation, EMT and Stemness in ER+ Cancer Cells. Diaz-Ruano AB, Martinez-Alarcon N, Perán M, Benabdellah K, Garcia-Martinez MLÁ, Preda O, Ramirez-Tortosa C, Gonzalez-Hernandez A, Marchal JA, Picon-Ruiz M. Int J Mol Sci. 2023 Jan 7;24(2):1221. doi: 10.3390/ijms24021221.
Molecular Mechanisms Linking Genes and Vitamins of the Complex B Related to One-Carbon Metabolism in Breast Cancer: An In Silico Functional Database Study. Gálvez-Navas JM, Molina-Montes E, Rodríguez-Barranco M, Ramírez-Tortosa M, Gil Á, Sánchez MJ. Int J Mol Sci. 2024 Jul 26;25(15):8175. doi: 10.3390/ijms25158175.
Lentiviral vectors for inducible, transactivator-free advanced therapy medicinal products: Application to CAR-T cells. Tristán-Manzano M, Maldonado-Pérez N, Justicia-Lirio P, Cortijo-Gutierréz M, Tristán-Ramos P, Blanco-Benítez C, Pavlovic K, Aguilar-González A, Muñoz P, Molina-Estevez FJ, Griesche V, Marchal JA, Heras SR, Benabdellah K, Martin F. Mol Ther Nucleic Acids. 2023 Mar 28;32:322-339. doi: 10.1016/j.omtn.2023.03.018.
Collagen Supplementation for Joint Health: The Link between Composition and Scientific Knowledge. Martínez-Puig D, Costa-Larrión E, Rubio-Rodríguez N, Gálvez-Martín P. Nutrients. 2023 Mar 8;15(6):1332. doi: 10.3390/nu15061332.
A Novel Hyaluronic Acid Matrix Ingredient with Regenerative, Anti-Aging and Antioxidant Capacity. Galvez-Martin P, Soto-Fernandez C, Romero-Rueda J, Cabañas J, Torrent A, Castells G, Martinez-Puig D. Int J Mol Sci. 2023 Mar 1;24(5):4774. doi: 10.3390/ijms24054774.
Preservation of critical quality attributes of mesenchymal stromal cells in 3D bioprinted structures by using natural hydrogel scaffolds. Martorell L, López-Fernández A, García-Lizarribar A, Sabata R, Gálvez-Martín P, Samitier J, Vives J. Biotechnol Bioeng. 2023 Sep;120(9):2717-2724. doi: 10.1002/bit.28381.
Development and characterization of a poloxamer hydrogel composed of human mesenchymal stromal cells (hMSCs) for reepithelization of skin injuries. Galocha-León C, Antich C, Voltes-Martínez A, Marchal JA, Mallandrich M, Halbaut L, Rodríguez-Lagunas MJ, Souto EB, Clares-Naveros B, Gálvez-Martín P. Int J Pharm. 2023 Nov 25;647:123535. doi: 10.1016/j.ijpharm.2023.123535.
Design and evaluation of a bilayered dermal/hypodermal 3D model using a biomimetic hydrogel formulation. Chocarro-Wrona C, López de Andrés J, Rioboó-Legaspi P, Pleguezuelos-Beltrán P, Antich C, De Vicente J, Gálvez-Martín P, López-Ruiz E, Marchal JA. Biomed Pharmacother. 2024 Aug;177:117051. doi: 10.1016/j.biopha.2024.117051.
Human mesenchymal stromal cells-laden crosslinked hyaluronic acid-alginate bioink for 3D bioprinting applications in tissue engineering. Galocha-León C, Antich C, Voltes-Martínez A, Marchal JA, Mallandrich M, Halbaut L, Souto EB, Gálvez-Martín P, Clares-Naveros B. Drug Deliv Transl Res. 2024 Apr 25. doi: 10.1007/s13346-024-01596-9.
ZCCHC3 is a stress granule zinc knuckle protein that strongly suppresses LINE-1 retrotransposition. Goodier JL, Wan H, Soares AO, Sanchez L, Selser JM, Pereira GC, Karma S, García-Pérez JL, Kazazian HH Jr, García Cañadas MM. PLoS Genet. 2023 Jul 5;19(7):e1010795. doi: 10.1371/journal.pgen.1010795.
Variable patterns of retrotransposition in different HeLa strains provide mechanistic insights into SINE RNA mobilization processes. Moldovan JB, Kopera HC, Liu Y, Garcia-Canadas M, Catalina P, Leone PE, Sanchez L, Kitzman JO, Kidd JM, Garcia-Perez JL, Moran JV. Nucleic Acids Res. 2024 Jul 22;52(13):7761-7779. doi: 10.1093/nar/gkae448.
Variable patterns of retrotransposition in different HeLa strains provide mechanistic insights into SINE RNA mobilization processes. Moldovan JB, Kopera HC, Liu Y, Garcia-Canadas M, Catalina P, Leone PE, Sanchez L, Kitzman JO, Kidd JM, Garcia-Perez JL, Moran JV. bioRxiv [Preprint]. 2024 May 3:2024.05.03.592410. doi: 10.1101/2024.05.03.592410.
Editorial: Investigation of the biological properties of natural products using experimental approaches and in silico methods. Mali SN, Dos Santos CBR, Campos Rosa J, Neves Cruz J. Front Chem. 2024 Apr 17;12:1406883. doi: 10.3389/fchem.2024.1406883.
New amidine-benzenesulfonamides as iNOS inhibitors for the therapy of the triple negative breast cancer. Carrión MD, Rubio-Ruiz B, Franco-Montalban F, Amoia P, Zuccarini MC, De Simone C, Camacho ME, Amoroso R, Maccallini C. Eur J Med Chem. 2023 Feb 15;248:115112. doi: 10.1016/j.ejmech.2023.115112.
New substituted benzoxazine derivatives as potent inducers of membrane permeability and cell death. Conejo-García A, Jiménez-Martínez Y, Cámara R, Franco-Montalbán F, Peña-Martín J, Boulaiz H, Carrión MD. Bioorg Med Chem. 2024 Sep 1;111:117849. doi: 10.1016/j.bmc.2024.117849.
N-aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: Design, synthesis, computational studies, and antitumor effect. Espejo-Román JM, Rubio-Ruiz B, Chayah-Ghaddab M, Vega-Gutierrez C, García-García G, Muguruza-Montero A, Domene C, Sánchez-Martín RM, Cruz-López O, Conejo-García A. Eur J Med Chem. 2023 Oct 5;258:115570. doi: 10.1016/j.ejmech.2023.115570
Preclinical evaluation of bozepinib in bladder cancer cell lines: modulation of the NPP1 enzyme. da Silva ÁC, Scholl JN, de Fraga Dias A, Weber AF, Morrone FB, Cruz-López O, Conejo-García A, Campos JM, Sévigny J, Figueiró F, Battastini AMO. Purinergic Signal. 2023 Oct 31. doi: 10.1007/s11302-023-09975-6.
Synthesis and Anti-Diabetic Activity of an 8-Purine Derivative as a Novel DPP-4 Inhibitor in Obese Diabetic Zücker Rats. Chayah M, Luque-González A, Gómez-Pérez V, Salagre D, Al-Shdaifat A, Campos JM, Conejo-García A, Agil A. Drug Des Devel Ther. 2024 Apr 10;18:1133-1141. doi: 10.2147/DDDT.S450917.
Self-Assembled Lanthanide Antenna Glutathione Sensor for the Study of Immune Cells. Fueyo-González F, Espinar-Barranco L, Herranz R, Alkorta I, Crovetto L, Fribourg M, Paredes JM, Orte A, González-Vera JA. ACS Sens. 2022 Jan 28;7(1):322-330. doi: 10.1021/acssensors.1c02439. Epub 2022 Jan 15.
Photosensitizing properties and subcellular localisation of 3,4-dihydro-β-carbolines harmaline and harmalol. Denofrio MP, Paredes JM, Yañuk JG, Giron MD, Salto R, Talavera EM, Crovetto L, Cabrerizo FM. Photochem Photobiol Sci. 2023 Mar;22(3):487-501. doi: 10.1007/s43630-022-00328-7.
Inhibition of hepatic oxalate overproduction ameliorates metabolic dysfunction-associated steatohepatitis. Das S, Finney AC, Anand SK, Rohilla S, Liu Y, Pandey N, Ghrayeb A, Kumar D, Nunez K, Liu Z, Arias F, Zhao Y, Pearson-Gallion BH, McKinney MP, Richard KSE, Gomez-Vidal JA, Abdullah CS, Cockerham ED, Eniafe J, Yurochko AD, Magdy T, Pattillo CB, Kevil CG, Razani B, Bhuiyan MS, Seeley EH, Galliano GE, Wei B, Tan L, Mahmud I, Surakka I, Garcia-Barrio MT, Lorenzi PL, Gottlieb E, Salido E, Zhang J, Orr AW, Liu W, Diaz-Gavilan M, Chen YE, Dhanesha N, Thevenot PT, Cohen AJ, Yurdagul A Jr, Rom O. Nat Metab. 2024 Sep 27. doi: 10.1038/s42255-024-01134-4.
Enhanced NSAIDs Solubility in Drug-Drug Formulations with Ciprofloxacin. Acebedo-Martínez FJ, Domínguez-Martín A, Alarcón-Payer C, Sevillano-Páez A, Verdugo-Escamilla C, González-Pérez JM, Martínez-Checa F, Choquesillo-Lazarte D. Int J Mol Sci. 2023 Feb 7;24(4):3305. doi: 10.3390/ijms24043305.
Rational Coformer Selection in the Development of 6-Propyl-2-thiouracil Pharmaceutical Cocrystals. Acebedo-Martínez FJ, Alarcón-Payer C, Verdugo-Escamilla C, Martín J, Frontera A, Domínguez-Martín A, Gómez-Morales J, Choquesillo-Lazarte D. Pharmaceuticals (Basel). 2023 Feb 28;16(3):370. doi: 10.3390/ph16030370.
Metformin-NSAIDs Molecular Salts: A Path towards Enhanced Oral Bioavailability and Stability. Acebedo-Martínez FJ, Domínguez-Martín A, Alarcón-Payer C, Garcés-Bastida C, Verdugo-Escamilla C, Gómez-Morales J, Choquesillo-Lazarte D. Pharmaceutics. 2023 Jan 29;15(2):449. doi: 10.3390/pharmaceutics15020449.
Optical Binding-Driven Micropatterning and Photosculpting with Silver Nanorods. Gonzalez-Garcia MC, Garcia-Fernandez E, Hueso JL, Paulo PMR, Orte A. Small Methods. 2023 Sep;7(9):e2300076. doi: 10.1002/smtd.202300076.
Repairing and Preventing Photooxidation of Few-Layer Black Phosphorus with β-Carotene. Singh M, Ingle A, González A, Mariathomas P, Ramanathan R, Taylor PD, Christofferson AJ, Spencer MJS, Low MX, Ahmed T, Walia S, Trasobares S, Manzorro R, Calvino JJ, García-Fernández E, Orte A, Dominguez-Vera JM, Bansal V. ACS Nano. 2023 May 9;17(9):8083-8097. doi: 10.1021/acsnano.2c10232.
Cytotoxic evaluation of YSL-109 in a triple negative breast cancer cell line and toxicological evaluations. Sixto-López Y, Ordaz-Pichardo C, Gómez-Vidal JA, Rosales-Hernández MC, Correa-Basurto J. Naunyn Schmiedebergs Arch Pharmacol. 2023 Jun;396(6):1211-1222. doi: 10.1007/s00210-023-02396-7.
Small-molecule TIP60 inhibitors enhance regulatory T cell induction through TIP60-P300 acetylation crosstalk. Fueyo-González F, Vilanova G, Ningoo M, Marjanovic N, González-Vera JA, Orte Á, Fribourg M. iScience. 2023 Nov 19;26(12):108491. doi: 10.1016/j.isci.2023.108491. eCollection 2023 Dec 15.
Small Fluorogenic Amino Acids for Peptide-Guided Background-Free Imaging. de Moliner F, Konieczna Z, Mendive-Tapia L, Saleeb RS, Morris K, Gonzalez-Vera JA, Kaizuka T, Grant SGN, Horrocks MH, Vendrell M. Angew Chem Int Ed Engl. 2023 Jan 23;62(4):e202216231. doi: 10.1002/anie.202216231. Epub 2022 Dec 14.
Small Fluorogenic Amino Acids for Peptide-Guided Background-Free Imaging. de Moliner F, Konieczna Z, Mendive-Tapia L, Saleeb RS, Morris K, Gonzalez-Vera JA, Kaizuka T, Grant SGN, Horrocks MH, Vendrell M. Angew Chem Weinheim Bergstr Ger. 2023 Jan 23;135(4):e202216231. doi: 10.1002/ange.202216231. Exchangeable Self-Assembled Lanthanide Antennas for PLIM Microscopy. Ruiz-Arias A, Fueyo-González F, Izquierdo-García C, Navarro A, Gutiérrez-Rodríguez M, Herranz R, Burgio C, Reinoso A, Cuerva JM, Orte A, González-Vera JA. Angew Chem Int Ed Engl. 2024 Feb 5;63(6):e202314595. doi: 10.1002/anie.202314595.
Multiple pathways for lanthanide sensitization in self-assembled aqueous complexes. Navarro A, Ruiz-Arias A, Fueyo-González F, Izquierdo-García C, Peña-Ruiz T, Gutiérrez-Rodríguez M, Herranz R, Cuerva JM, González-Vera JA, Orte A. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Dec 15;323:124926. doi: 10.1016/j.saa.2024.124926. Epub 2024 Aug 3. PMID: 39116593
New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action. Luque-Navarro PM, Carrasco-Jiménez MP, Goracci L, Paredes JM, Espinar-Barranco L, Valverde-Pozo J, Torretta A, Parisini E, Mariotto E, Marchioro C, Laso A, Marco C, Viola G, Lanari D, López Cara LC. Eur J Med Chem. 2023 Jan 15;246:115003. doi: 10.1016/j.ejmech.2022.115003
Directing novel ChoKα1 inhibitors using MamC-mediated biomimetic magnetic nanoparticles: a way to improve specificity and efficiency. Sola-Leyva A, Jabalera Y, Jimenez-Carretero M, Lázaro M, Pozo-Gualda T, García-Vargas PJ, Luque-Navarro PM, Fasiolo A, López-Cara LC, Iglesias GR, Paz Carrasco-Jiménez M, Jiménez-López C. Bioorg Chem. 2024 Oct;151:107693. doi: 10.1016/j.bioorg.2024.107693.
Supramolecular Nature of Multicomponent Crystals Formed from 2,2'-Thiodiacetic Acid with 2,6-Diaminopurine or N9-(2-Hydroxyethyl)adenine. Belmont-Sánchez JC, Choquesillo-Lazarte D, García-Rubiño ME, Matilla-Hernández A, Niclós-Gutiérrez J, Castiñeiras A, Frontera A. Int J Mol Sci. 2023 Dec 12;24(24):17381. doi: 10.3390/ijms242417381.
Comprehensive physicochemical characterization of a peptide-based medicine: Teduglutide (Revestive®) structural description and stress testing. Pérez-Robles R, Salmerón-García A, Hermosilla J, Torrente-López A, Clemente-Bautista S, Jiménez-Lozano I, Cabañas-Poy MJ, Cabeza J, Navas N. Eur J Pharm Biopharm. 2023 Mar;184:103-115. doi: 10.1016/j.ejpb.2023.01.001.
Practical study on the impact of injection conditions in gradient elution mode for the analysis of therapeutic proteins when using very short columns. Pérez-Robles R, Fekete S, Navas N, Guillarme D. J Chromatogr A. 2023 Oct 25;1709:464359. doi: 10.1016/j.chroma.2023.464359.
Analysing the In-Use Stability of mRNA-LNP COVID-19 Vaccines Comirnaty™ (Pfizer) and Spikevax™ (Moderna): A Comparative Study of the Particulate. Hermosilla J, Alonso-García A, Salmerón-García A, Cabeza-Barrera J, Medina-Castillo AL, Pérez-Robles R, Navas N. Vaccines (Basel). 2023 Oct 25;11(11):1635. doi: 10.3390/vaccines11111635
Improved sample introduction approach in hydrophilic interaction liquid chromatography to avoid breakthrough of proteins. Pérez-Robles R, Fekete S, Kormány R, Navas N, Guillarme D. J Chromatogr A. 2024 Jan 4;1713:464498. doi: 10.1016/j.chroma.2023.464498
Comprehensive physicochemical and functional analysis of pembrolizumab based on controlled degradation studies: Impact on antigen-antibody binding. Torrente-López A, Hermosilla J, Salmerón-García A, Cabeza J, Ruiz-Martínez A, Navas N. Eur J Pharm Biopharm. 2024 Jan;194:131-147. doi: 10.1016/j.ejpb.2023.12.005.
Comprehensive Analysis of Cetuximab Critical Quality Attributes: Impact of Handling on Antigen-Antibody Binding. Torres-García A, Torrente-López A, Hermosilla J, Hernández A, Salmerón-García A, Cabeza J, Navas N. Pharmaceutics. 2024 Sep 19;16(9):1222. doi: 10.3390/pharmaceutics16091222.
Synthesis, Structural Characterisation, and Electrochemical Properties of Copper(II) Complexes with Functionalized Thiosemicarbazones Derived from 5-Acetylbarbituric Acid. Castiñeiras A, Fernández-Hermida N, García-Santos I, Gómez-Rodríguez L, Frontera A, Niclós-Gutiérrez J. Molecules. 2024 May 10;29(10):2245. doi: 10.3390/molecules29102245.
H(N3)dap (Hdap = 2,6-Diaminopurine) Recognition by Cu2(EGTA): Structure, Physical Properties, and Density Functional Theory Calculations of [Cu4(μ-EGTA)2(μ-H(N3)dap)2(H2O)2]·7H2O. Mousavi H, García-Rubiño ME, Choquesillo-Lazarte D, Castiñeiras A, Lezama L, Frontera A, Niclós-Gutiérrez J. Molecules. 2023 Aug 26;28(17):6263. doi: 10.3390/molecules28176263.
The Copper(II)-Thiodiacetate (tda) Chelate as Efficient Receptor of N9-(2-Hydroxyethyl)Adenine (9heade): Synthesis, Molecular and Crystal Structures, Physical Properties and DFT Calculations of [Cu(tda)(9heade)(H2O)]·2H2O. Rosales-Martínez C, Matilla-Hernádez A, Choquesillo-Lazarte D, Frontera A, Castiñeiras A, Niclós-Gutiérrez J. Molecules. 2023 Aug 2;28(15):5830. doi: 10.3390/molecules28155830.
Characterization and Molecular Modelling of Non-Antibiotic Nanohybrids for Wound Healing Purposes. Valentino C, Martínez Rodríguez T, Borrego-Sánchez A, Hernández Benavides P, Arrebola Vargas F, Paredes JM, Rossi S, Sainz Díaz CI, Sandri G, Grisoli P, Medina Pérez MDM, Aguzzi C. Pharmaceutics. 2023 Apr 4;15(4):1140. doi: 10.3390/pharmaceutics15041140.
Formulative Study and Characterization of Novel Biomaterials Based on Chitosan/Hydrolyzed Collagen Films. Martínez Rodríguez T, Valentino C, Rodríguez Pozo FR, Hernández Benavides P, Arrebola Vargas F, Paredes JM, Sainz-Díaz CI, Iglesias GR, Rossi S, Sandri G, Medina Pérez MDM, Aguzzi C. J Funct Biomater. 2024 Mar 11;15(3):69. doi: 10.3390/jfb15030069.
Ratiometric Two-Photon Near-Infrared Probe to Detect DPP IV in Human Plasma, Living Cells, Human Tissues, and Whole Organisms Using Zebrafish. Valverde-Pozo J, Paredes JM, Widmann TJ, Griñan-Lison C, Ceccarelli G, Gioiello A, Garcia-Rubiño ME, Marchal JA, Alvarez-Pez JM, Talavera EM. ACS Sens. 2023 Mar 24;8(3):1064-1075. doi: 10.1021/acssensors.2c02025.
Advanced Imaging Methodology in Bacterial Biofilms with a Fluorescent Enzymatic Sensor for pepN Activity. Valverde-Pozo J, Paredes JM, García-Rubiño ME, Girón MD, Salto R, Alvarez-Pez JM, Talavera EM. Biosensors (Basel). 2024 Sep 3;14(9):424. doi: 10.3390/bios14090424.
In Cellulo Bioorthogonal Catalysis by Encapsulated AuPd Nanoalloys: Overcoming Intracellular Deactivation. Rubio-Ruiz B, Pérez-López AM, Uson L, Ortega-Liebana MC, Valero T, Arruebo M, Hueso JL, Sebastian V, Santamaria J, Unciti-Broceta A. Nano Lett. 2023 Feb 8;23(3):804-811. doi: 10.1021/acs.nanolett.2c03593.
A Novel Insular/Orbital-Prelimbic Circuit That Prevents Persistent Avoidance in a Rodent Model of Compulsive Behavior. Martínez-Rivera FJ, Pérez-Torres J, Velázquez-Díaz CD, Sánchez-Navarro MJ, Huertas-Pérez CI, Diehl MM, Phillips ML, Haber SN, Quirk GJ. Biol Psychiatry. 2023 Jun 1;93(11):1000-1009. doi: 10.1016/j.biopsych.2022.02.008.
Cortistatin deficiency reveals a dysfunctional brain endothelium with impaired gene pathways, exacerbated immune activation, and disrupted barrier integrity. Castillo-González J, Ruiz JL, Serrano-Martínez I, Forte-Lago I, Ubago-Rodriguez A, Caro M, Pérez-Gómez JM, Benítez-Troncoso A, Andrés-León E, Sánchez-Navarro M, Luque RM, González-Rey E. J Neuroinflammation. 2023 Oct 4;20(1):226. doi: 10.1186/s12974-023-02908-5.
GPR-160 Receptor Signaling in the Dorsal Vagal Complex of Male Rats Modulates Meal Microstructure and CART-Mediated Hypophagia. Sanchez-Navarro MJ, Borner T, Reiner BC, Crist RC, Samson WK, Yosten GLC, Stein L, Hayes MR. Nutrients. 2023 May 11;15(10):2268. doi: 10.3390/nu15102268. PMID: 37242151 Free PMC article.
Natural and Synthetic Clay Minerals in the Pharmaceutical and Biomedical Fields. Nomicisio C, Ruggeri M, Bianchi E, Vigani B, Valentino C, Aguzzi C, Viseras C, Rossi S, Sandri G. Pharmaceutics. 2023 Apr 29;15(5):1368. doi: 10.3390/pharmaceutics15051368.
Characterization and Molecular Modelling of Non-Antibiotic Nanohybrids for Wound Healing Purposes. Valentino C, Martínez Rodríguez T, Borrego-Sánchez A, Hernández Benavides P, Arrebola Vargas F, Paredes JM, Rossi S, Sainz Díaz CI, Sandri G, Grisoli P, Medina Pérez MDM, Aguzzi C. Pharmaceutics. 2023 Apr 4;15(4):1140. doi: 10.3390/pharmaceutics15041140.
Formulative Study and Characterization of Novel Biomaterials Based on Chitosan/Hydrolyzed Collagen Films. Martínez Rodríguez T, Valentino C, Rodríguez Pozo FR, Hernández Benavides P, Arrebola Vargas F, Paredes JM, Sainz-Díaz CI, Iglesias GR, Rossi S, Sandri G, Medina Pérez MDM, Aguzzi C. J Funct Biomater. 2024 Mar 11;15(3):69. doi: 10.3390/jfb15030069.
Antibiotic Nanoparticles-Loaded Wound Dressings Against Pseudomonas aeruginosa's Skin Infection: A Systematic Review. Quiñones-Vico MI, Ubago-Rodríguez A, Fernández-González A, Sanabria-de la Torre R, Sierra-Sánchez Á, Montero-Vilchez T, Sánchez-Díaz M, Arias JL, Arias-Santiago S. Int J Nanomedicine. 2024 Aug 2;19:7895-7926. doi: 10.2147/IJN.S469724.
Multi-stimuli-responsive chitosan-functionalized magnetite/poly(ε-caprolactone) nanoparticles as theranostic platforms for combined tumor magnetic resonance imaging and chemotherapy. García-García G, Caro C, Fernández-Álvarez F, García-Martín ML, Arias JL. Nanomedicine. 2023 Aug;52:102695. doi: 10.1016/j.nano.2023.102695
Dosimetry in cranial photobiomodulation therapy: effect of cranial thickness and bone density. Castaño-Castaño S, Zorzo C, Martínez-Esteban JÁ, Arias JL. Lasers Med Sci. 2024 Feb 22;39(1):76. doi: 10.1007/s10103-024-04024-z.
Magnetic and pH-responsive magnetite/chitosan (core/shell) nanoparticles for dual-targeted methotrexate delivery in cancer therapy. Medina-Moreno A, El-Hammadi MM, Martínez-Soler GI, Ramos JG, García-García G, Arias JL. Drug Deliv Transl Res. 2024 Sep 5. doi: 10.1007/s13346-024-01701-y. Permeation Protection by Waterproofing Mucosal Membranes. Coderch L, Alonso C, Calpena AC, Pérez-García ML, Clares-Naveros B, Ramos A, Martí M. Pharmaceutics. 2023 Nov 29;15(12):2698. doi: 10.3390/pharmaceutics15122698.
A Synthetic Model of the Mucosa for Oral Penetration Studies. Alonso C, Martí M, Ramos A, Calpena AC, Clares-Naveros B, Coderch L. Membranes (Basel). 2023 Dec 12;13(12):905. doi: 10.3390/membranes13120905.
Caspofungin-Loaded Formulations for Treating Ocular Infections Caused by Candida spp. Pérez-González N, Rodríguez-Lagunas MJ, Calpena-Campmany AC, Bozal-de Febrer N, Halbaut-Bellowa L, Mallandrich M, Clares-Naveros B. Gels. 2023 Apr 20;9(4):348. doi: 10.3390/gels9040348
Development and characterization of a poloxamer hydrogel composed of human mesenchymal stromal cells (hMSCs) for reepithelization of skin injuries. Galocha-León C, Antich C, Voltes-Martínez A, Marchal JA, Mallandrich M, Halbaut L, Rodríguez-Lagunas MJ, Souto EB, Clares-Naveros B, Gálvez-Martín P. Int J Pharm. 2023 Nov 25;647:123535. doi: 10.1016/j.ijpharm.2023.123535.
Gel Formulations with an Echinocandin for Cutaneous Candidiasis: The Influence of Azone and Transcutol on Biopharmaceutical Features. Pérez-González N, Espinoza LC, Rincón M, Sosa L, Mallandrich M, Suñer-Carbó J, Bozal-de Febrer N, Calpena AC, Clares-Naveros B. Gels. 2023 Apr 6;9(4):308. doi: 10.3390/gels9040308.
Human mesenchymal stromal cells-laden crosslinked hyaluronic acid-alginate bioink for 3D bioprinting applications in tissue engineering. Galocha-León C, Antich C, Voltes-Martínez A, Marchal JA, Mallandrich M, Halbaut L, Souto EB, Gálvez-Martín P, Clares-Naveros B. Drug Deliv Transl Res. 2024 Apr 25. doi: 10.1007/s13346-024-01596-9.
Dopamine-loaded chitosan-coated solid lipid nanoparticles as a promise nanocarriers to the CNS. Ortega Martínez E, Morales Hernández ME, Castillo-González J, González-Rey E, Ruiz Martínez MA. Neuropharmacology. 2024 May 15;249:109871. doi: 10.1016/j.neuropharm.2024.109871 Novel Ti surface coated with PVA hydrogel and chitosan nanoparticles with antibacterial drug release: An experimental in vitro study. Carrazco Ávila PY, Arias Moliz T, Rosales Leal JI, Baca P, Rodríguez Valverde MÁ, Morales Hernandez ME. Clin Implant Dent Relat Res. 2024 Apr;26(2):427-441. doi: 10.1111/cid.13305.
Exploring the Nutritional and Bioactive Potential of Olive Leaf Residues: A Focus on Minerals and Polyphenols in the Context of Spain's Olive Oil Production. Ronca CL, Duque-Soto C, Samaniego-Sánchez C, Morales-Hernández ME, Olalla-Herrera M, Lozano-Sánchez J, Giménez Martínez R. Foods. 2024 Mar 28;13(7):1036. doi: 10.3390/foods13071036.
Microbial composition of Saharan dust plumes deposited as red rain in Granada (Southern Spain). Navarro A, Del Moral A, Weber B, Weber J, Molinero A, Delgado R, Párraga J, Martínez-Checa F. Sci Total Environ. 2024 Feb 25;913:169745. doi: 10.1016/j.scitotenv.2023.169745. Thixotropic Hydrogels Based on Laponite® and Cucurbituril for Delivery of Lipophilic Drug Molecules. Massaro M, Cinà G, Borrego-Sánchez A, Sainz-Díaz CI, Viseras-Iborra C, Sánchez-Espejo R, de Melo Barbosa R, Leone F, Pibiri I, Noto R, Riela S. Chempluschem. 2024 Jan;89(1):e202300592. doi: 10.1002/cplu.202300592
A microfluidic labyrinth self-assembled by a chemical garden. Testón-Martínez S, Huertas-Roldán T, Knoll P, Barge LM, Sainz-Díaz CI, Cartwright JHE. Phys Chem Chem Phys. 2023 Nov 15;25(44):30469-30476. doi: 10.1039/d3cp02929h.
Adsorption of Capsaicin into the Nanoconfined Interlayer Space of Montmorillonite by DFT Calculations. Soriano-Correa C, Pérez de la Luz A, Sainz-Díaz CI. J Pharm Sci. 2023 Mar;112(3):798-807. doi: 10.1016/j.xphs.2022.10.024
Exploiting the interaction between halloysite and charged PNAs for their controlled release. Riela S, Borrego-Sánchez A, Cauteruccio S, de Melo Barbosa R, Massaro M, Sainz-Díaz CI, Sánchez-Espejo R, Viseras-Iborra C, Licandro E. J Mater Chem B. 2023 Jul 19;11(28):6685-6696. doi: 10.1039/d3tb00637a.
Characterization and Molecular Modelling of Non-Antibiotic Nanohybrids for Wound Healing Purposes. Valentino C, Martínez Rodríguez T, Borrego-Sánchez A, Hernández Benavides P, Arrebola Vargas F, Paredes JM, Rossi S, Sainz Díaz CI, Sandri G, Grisoli P, Medina Pérez MDM, Aguzzi C. Pharmaceutics. 2023 Apr 4;15(4):1140. doi: 10.3390/pharmaceutics15041140.
Adsorption of Ciprofloxacin on Clay Minerals in Argentinian Santa Rosa-Corrientes Soils. Jorge NL, Garrafa MV, Romero JM, Jorge MJ, Jorge LC, Delfino MR, Meruvia-Rojas YV, Hernández-Laguna A, Sainz-Díaz CI. Molecules. 2024 Apr 12;29(8):1760. doi: 10.3390/molecules29081760.
Experimental and Computational Study for the Design of Sulfathiazole Dosage Form with Clay Mineral. Moreno-Domínguez E, Borrego-Sánchez A, Sánchez-Espejo R, Viseras C, Sainz-Díaz CI. Pharmaceutics. 2023 Feb 8;15(2):575. doi: 10.3390/pharmaceutics15020575.
Thixotropic Hydrogels Based on Laponite® and Cucurbituril for Delivery of Lipophilic Drug Molecules. Massaro M, Cinà G, Borrego-Sánchez A, Sainz-Díaz CI, Viseras-Iborra C, Sánchez-Espejo R, de Melo Barbosa R, Leone F, Pibiri I, Noto R, Riela S. Chempluschem. 2024 Jan;89(1):e202300370. doi: 10.1002/cplu.202300370.
Hectorite/Phenanthroline-Based Nanomaterial as Fluorescent Sensor for Zn Ion Detection: A Theoretical and Experimental Study. Massaro M, Borrego-Sánchez A, Viseras-Iborra C, Cinà G, García-Villén F, Liotta LF, Lopez Galindo A, Pimentel C, Sainz-Díaz CI, Sánchez-Espejo R, Riela S. Nanomaterials (Basel). 2024 May 19;14(10):880. doi: 10.3390/nano14100880.
Bentonite- and Palygorskite-Based Gels for Topical Drug Delivery Applications. Ruggeri M, Sánchez-Espejo R, Casula L, Sandri G, Perioli L, Cardia MC, Lai F, Viseras C. Pharmaceutics. 2023 Apr 16;15(4):1253. doi: 10.3390/pharmaceutics15041253.
Nutritional and Functional Properties of Novel Italian Spray-Dried Cricket Powder. Ruggeri M, Bianchi E, Vigani B, Sánchez-Espejo R, Spano M, Totaro Fila C, Mannina L, Viseras C, Rossi S, Sandri G. Antioxidants (Basel). 2023 Jan 2;12(1):112. doi: 10.3390/antiox12010112.
Antioxidant Efficacy and “In Vivo” Safety of a Bentonite/Vitamin C Hybrid. Hernández D, Montalvo A, Pérez I, Charnay C, Sánchez-Espejo R, Cerezo P, Viseras C, Riela S, Cinà G, Rivera A. Pharmaceutics. 2023 Apr 7;15(4):1171. doi: 10.3390/pharmaceutics15041171.
Modification of halloysite lumen with dopamine derivatives as filler for antibiofilm coating. Massaro M, Laura Alfieri M, Rizzo G, Babudri F, Barbosa de Melo R, Faddetta T, Gallo G, Napolitano A, Sanchèz-Espejo R, Viseras Iborra C, Riela S. J Colloid Interface Sci. 2023 Sep 15;646:910-921. doi: 10.1016/j.jcis.2023.05.121
Nanoformulations based on collagenases loaded into halloysite/Veegum® clay minerals for potential pharmaceutical applications. Massaro M, Ghersi G, de Melo Barbosa R, Campora S, Rigogliuso S, Sànchez-Espejo R, Viseras-Iborra C, Riela S. Colloids Surf B Biointerfaces. 2023 Oct;230:113511. doi: 10.1016/j.colsurfb.2023.113511.
Investigation into Brazilian Palygorskite for Its Potential Use as Pharmaceutical Excipient: Perspectives and Applications. Meirelles LMA, Barbosa RM, Sanchez-Espejo R, García-Villén F, Perioli L, Viseras C, Moura TFALE, Raffin FN. Materials (Basel). 2023 Jul 12;16(14):4962. doi: 10.3390/ma16144962.
Design and development of polydioxanone scaffolds for skin tissue engineering manufactured via green process. Miele D, Nomicisio C, Musitelli G, Boselli C, Icaro Cornaglia A, Sànchez-Espejo R, Vigani B, Viseras C, Rossi S, Sandri G. Int J Pharm. 2023 Mar 5;634:122669. doi: 10.1016/j.ijpharm.2023.122669. Thixotropic Hydrogels Based on Laponite® and Cucurbituril for Delivery of Lipophilic Drug Molecules. Massaro M, Cinà G, Borrego-Sánchez A, Sainz-Díaz CI, Viseras-Iborra C, Sánchez-Espejo R, de Melo Barbosa R, Leone F, Pibiri I, Noto R, Riela S. Chempluschem. 2024 Jan;89(1):e202300592. doi: 10.1002/cplu.202300592.
Zeolites as Ingredients of Medicinal Products. Souza IMS, García-Villén F, Viseras C, Perger SBC. Pharmaceutics. 2023 Apr 28;15(5):1352. doi: 10.3390/pharmaceutics15051352.
Biocomposite for Prolonged Release of Water-Soluble Drugs. Meirelles LMA, de Melo Barbosa R, de Almeida Júnior RF, Machado PRL, Perioli L, Viseras C, Raffin FN. Pharmaceutics. 2023 Jun 14;15(6):1722. doi: 10.3390/pharmaceutics15061722.
Environmentally Friendly Strategies for Formulating Vegetable Oil-Based Nanoparticles for Anticancer Medicine. Freire N, Barbosa RM, García-Villén F, Viseras C, Perioli L, Fialho R, Albuquerque E. Pharmaceutics. 2023 Jul 8;15(7):1908. doi: 10.3390/pharmaceutics15071908.
Montmorillonite-Rifampicin Nanohybrid for pH-Responsive Release of the Tuberculostatic. Damasceno Junior E, Barbosa RM, da Silva RCD, Costa FDS, da Silva DR, Viseras C, Perioli L, Fernandes NS. Pharmaceutics. 2023 Feb 3;15(2):512. doi: 10.3390/pharmaceutics15020512.
Conventional and PEGylated Liposomes as Vehicles of Copaifera sabulicola. Blanco IMR, Barbosa RM, Borges JMP, de Melo SABV, El-Bachá RDS, Viseras C, Severino P, Sanchez-Lopez E, Souto EB, Cabral-Albuquerque E. Pharmaceutics. 2023 Feb 16;15(2):671. doi: 10.3390/pharmaceutics15020671.
Bentonite- and Palygorskite-Based Gels for Topical Drug Delivery Applications. Ruggeri M, Sánchez-Espejo R, Casula L, Sandri G, Perioli L, Cardia MC, Lai F, Viseras C. Pharmaceutics. 2023 Apr 16;15(4):1253. doi: 10.3390/pharmaceutics15041253.
Electrospun Scaffolds Based on Poly(butyl cyanoacrylate) for Tendon Tissue Engineering. Bianchi E, Vigani B, Ruggeri M, Del Favero E, Ricci C, Grisoli P, Ferraretto A, Rossi S, Viseras C, Sandri G. Int J Mol Sci. 2023 Feb 6;24(4):3172. doi: 10.3390/ijms24043172.