Health literacy: A field for pharmaceutical intervention. Ferreira Alfaya FJ, Zarzuelo Romero MJ. Res Social Adm Pharm. 2022 Nov;18(11):3867-3869. doi: 10.1016/j.sapharm.2022.06.011.
Comprehensibility of South African pictograms by sub-Saharan African prospective-users. Ferreira-Alfaya FJ. Patient Educ Couns. 2023 Oct;115:107930. doi: 10.1016/j.pec.2023.107930.
Pharmaceutical pictograms to improve textual comprehension: A systematic review. Ferreira-Alfaya FJ, Zarzuelo-Romero MJ, Cura Y. Res Social Adm Pharm. 2024 Feb;20(2):75-85. doi: 10.1016/j.sapharm.2023.11.007.
Comprehension of pharmaceutical pictograms in sub-Saharan migrants newly arriving in Europe: An exploratory study. Ferreira-Alfaya FJ. J Am Pharm Assoc (2003). 2024 Mar-Apr;64(2):535-539.e3. doi: 10.1016/j.japh.2023.12.021.
Comprehension of US Pharmacopeia and South African pictograms by sub-Saharan migrants who newly arrived in Europe. Ferreira-Alfaya FJ, Zarzuelo-Romero MJ, Cura Y. Res Social Adm Pharm. 2024 Jan;20(1):54-62. doi: 10.1016/j.sapharm.2023.09.001.
Alignment of Patient Information Leaflets with the Health Literacy Skills of Future End-Users: Are We on the Same Page? Ferreira-Alfaya FJ, Zarzuelo-Romero MJ, Cura Y. Health Commun. 2024 Aug 12:1-12. doi: 10.1080/10410236.2024.2388887.
Vitamin D-Related Single Nucleotide Polymorphisms as Risk Biomarker of Cardiovascular Disease. González Rojo P, Pérez Ramírez C, Gálvez Navas JM, Pineda Lancheros LE, Rojo Tolosa S, Ramírez Tortosa MDC, Jiménez Morales A. Int J Mol Sci. 2022 Aug 4;23(15):8686. doi: 10.3390/ijms23158686.
Polymeric Patches Based on Chitosan/Green Clay Composites and Hazelnut Shell Extract as Bio-Sustainable Medication for Wounds. Pérez Gutíerrez CL, Di Michele A, Pagano C, Puglia D, Luzi F, Beccari T, Ceccarini MR, Primavilla S, Valiani A, Vicino C, Ricci M, Viseras Iborra CA, Perioli L. Pharmaceutics. 2023 Jul 31;15(8):2057. doi: 10.3390/pharmaceutics15082057.
The Optimization of Pressure-Assisted Microsyringe (PAM) 3D Printing Parameters for the Development of Sustainable Starch-Based Patches. Pérez Gutiérrez CL, Cottone F, Pagano C, Di Michele A, Puglia D, Luzi F, Dominici F, Sinisi R, Ricci M, Viseras Iborra CA, Perioli L. Polymers (Basel). 2023 Sep 17;15(18):3792. doi: 10.3390/polym15183792.
Effect of genetic polymorphisms on therapeutic response in multiple sclerosis relapsing-remitting patients treated with interferon-beta. Martínez-Aguilar L, Pérez-Ramírez C, Maldonado-Montoro MDM, Carrasco-Campos MI, Membrive-Jiménez C, Martínez-Martínez F, García-Collado C, Calleja-Hernández MÁ, Ramírez-Tortosa MC, Jiménez-Morales A. Mutat Res Rev Mutat Res. 2020 Jul-Sep;785:108322. doi: 10.1016/j.mrrev.2020.108322.
Suitability of indexing terms in the MEDLINE bibliographic database on drug-related problems. Martínez-Aguilar L, Sanz-Valero J, Martínez-Martínez F, Faus MJ. Res Social Adm Pharm. 2023 Nov;19(11):1440-1445. doi: 10.1016/j.sapharm.2023.07.006.
Public interest in drug-related problems reflected in information search trends: an infodemiological study. Martínez-Aguilar L, Sanz-Lorente M, Martínez-Martínez F, Faus MJ, Sanz-Valero J. Daru. 2024 Jun 18. doi: 10.1007/s40199-024-00519-w.
Medication Review with Follow-Up for End-Stage Renal Disease: Drug-Related Problems and Negative Outcomes Associated with Medication-A Systematic Review. Pereira-Céspedes A, Jiménez-Morales A, Palomares-Bayo M, Martínez-Martínez F, Calleja-Hernández MÁ. J Clin Med. 2023 Aug 2;12(15):5080. doi: 10.3390/jcm12155080.
Factors Contributing to Negative Outcomes Associated with Medications and Drug-Related Problems in Kidney Replacement Therapy-A Hospital-Based Prospective Observational Study. Pereira-Céspedes A, Jiménez-Morales A, Polo-Moyano A, Palomares-Bayo M, Martínez-Martínez F, Calleja-Hernández MÁ. J Clin Med. 2024 Feb 12;13(4):1048. doi: 10.3390/jcm13041048.
Health-Related Quality of Life and Associated Factors in Patients Undergoing Kidney Replacement Therapies. Pereira-Céspedes A, Jiménez-Morales A, Polo-Moyano A, Spruce-Esparza E, Palomares-Bayo M, Martínez-Martínez F, Calleja-Hernández MÁ. Farm Hosp. 2024 Sep 17:S1130-6343(24)00143-0. doi: 10.1016/j.farma.2024.08.008.
Exploring Micromonospora as Phocoenamicins Producers. Kokkini M, González Heredia C, Oves-Costales D, de la Cruz M, Sánchez P, Martín J, Vicente F, Genilloud O, Reyes F. Mar Drugs. 2022 Dec 7;20(12):769. doi: 10.3390/md20120769.
New Phocoenamicin and Maklamicin Analogues from Cultures of Three Marine-Derived Micromonospora Strains. Kokkini M, Oves-Costales D, Sánchez P, Melguizo Á, Mackenzie TA, Pérez-Bonilla M, Martín J, Giusti A, de Witte P, Vicente F, Genilloud O, Reyes F. Mar Drugs. 2023 Aug 7;21(8):443. doi: 10.3390/md21080443
Phocoenamicins B and C, New Antibacterial Spirotetronates Isolated from a Marine Micromonospora sp. Pérez-Bonilla M, Oves-Costales D, de la Cruz M, Kokkini M, Martín J, Vicente F, Genilloud O, Reyes F. Mar Drugs. 2018 Mar 16;16(3):95. doi: 10.3390/md16030095.
Is advanced esophageal adenocarcinoma a distinct entity from intestinal subtype gastric cancer? Data from the AGAMENON-SEOM Registry. Alvarez-Manceñido F, Jimenez-Fonseca P, Carmona-Bayonas A, Arrazubi V, Hernandez R, Cano JM, Custodio A, Pericay Pijaume C, Aguado G, Martínez Lago N, Sánchez Cánovas M, Cacho Lavin D, Visa L, Martinez-Torron A, Arias-Martinez A, López F, Limón ML, Vidal Tocino R, Fernández Montes A, Alsina M, Pimentel P, Reguera P, Martín Carnicero A, Ramchandani A, Granja M, Azkarate A, Martín Richard M, Serra O, Hernández Pérez C, Hurtado A, Gil-Negrete A, Sauri T, Morales Del Burgo P, Gallego J. Gastric Cancer. 2021 Jul;24(4):926-936. doi: 10.1007/s10120-021-01169-6.
Sex and gender disparities in patients with advanced gastroesophageal adenocarcinoma: data from the AGAMENON-SEOM registry. Plazas JG, Arias-Martinez A, Lecumberri A, Martínez de Castro E, Custodio A, Cano JM, Hernandez R, Montes AF, Macias I, Pieras-Lopez A, Diez M, Visa L, Tocino RV, Lago NM, Limón ML, Gil M, Pimentel P, Mangas M, Granja M, Carnicero AM, Pérez CH, Gonzalez LG, Jimenez-Fonseca P, Carmona-Bayonas A. ESMO Open. 2022 Jun;7(3):100514. doi: 10.1016/j.esmoop.2022.100514.
External validity of docetaxel triplet trials in advanced gastric cancer: are there patients who still benefit? Jimenez-Fonseca P, Carmona-Bayonas A, Martínez de Castro E, Custodio A, Pericay Pijaume C, Hernandez R, Aguado G, Castro Unanua N, Cano JM, López F, Garrido M, Fernández Montes A, Visa L, Sánchez Cánovas M, Limón ML, Martínez Lago N, Pimentel P, Hurtado A, Azkárate A, Longo F, Diez M, Arias-Martinez A, Sauri T, Martín Carnicero A, Mangas M, Martín Richard M, Granja M, Ramchandani A, Hernández Pérez C, Cerdá P, Gil-Negrete A, Calvo M, Vidal Tocino R, Gallego J. Gastric Cancer. 2021 Mar;24(2):445-456. doi: 10.1007/s10120-020-01116-x.
Autoimmune hemolytic anemia, adverse event to venetoclax. Carriles C, Ordóñez-Fernández L, Arias-Martínez A, Menárguez-Blanc R, Rosado-María MC. Farm Hosp. 2019 Sep 1;43(5):166-167. doi: 10.7399/fh.11230.
Comment on 'Baseline patients' characteristics as predictors for therapeutic survival and response in patients with psoriasis on biological treatments'. Gómez-de Castro C, Mir-Bonafé M, Arias-Martínez A, Martínez-Camblor P, Díaz-Coto S, Santos-Juanes J. Australas J Dermatol. 2019 Aug;60(3):e258-e259. doi: 10.1111/ajd.13016.
Is there a preferred platinum and fluoropyrimidine regimen for advanced HER2-negative esophagogastric adenocarcinoma? Insights from 1293 patients in AGAMENON-SEOM registry. Arias-Martinez A, Martínez de Castro E, Gallego J, Arrazubi V, Custodio A, Fernández Montes A, Diez M, Hernandez R, Limón ML, Cano JM, Vidal-Tocino R, Macias I, Visa L, Martin Richard M, Sauri T, Hierro C, Gil M, Cerda P, Martínez Moreno E, Martínez Lago N, Mérida-García AJ, Gómez González L, García Navalón FJ, Ruiz Martín M, Marín G, López-López F, Ruperez Blanco AB, Fernández AF, Jimenez-Fonseca P, Carmona-Bayonas A, Alvarez-Manceñido F. Clin Transl Oncol. 2024 Jul;26(7):1674-1686. doi: 10.1007/s12094-024-03388-6.
Pharmacogenetic polymorphisms affecting bisoprolol response. Castaño-Amores C, Díaz-Villamarín X, Pérez-Gutiérrez AM, Antúnez-Rodríguez A, Pozo-Agundo A, Moreno-Escobar E, Sánchez-Ramos JG, Martínez-González LJ, Dávila-Fajardo CL. Biomed Pharmacother. 2021 Oct;142:112069. doi: 10.1016/j.biopha.2021.112069
Genetic polymorphisms in ADRB1, ADRB2 and CYP2D6 genes and response to beta-blockers in patients with acute coronary syndrome. Castaño-Amores C, Antúnez-Rodríguez A, Pozo-Agundo A, García-Rodríguez S, Martínez-González LJ, Dávila-Fajardo CL. Biomed Pharmacother. 2023 Dec 31;169:115869. doi: 10.1016/j.biopha.2023.115869.
Precision Medicine in Childhood Cancer: The Influence of Genetic Polymorphisms on Vincristine-Induced Peripheral Neuropathy. Marangoni-Iglecias L, Rojo-Tolosa S, Márquez-Pete N, Cura Y, Moreno-Toro N, Membrive-Jiménez C, Sánchez-Martin A, Pérez-Ramírez C, Jiménez-Morales A. Int J Mol Sci. 2024 Aug 13;25(16):8797. doi: 10.3390/ijms25168797.
Role of Single-Nucleotide Polymorphisms in Genes Implicated in Capecitabine Pharmacodynamics on the Effectiveness of Adjuvant Therapy in Colorectal Cancer. Cura Y, Sánchez-Martín A, Márquez-Pete N, González-Flores E, Martínez-Martínez F, Pérez-Ramírez C, Jiménez-Morales A. Int J Mol Sci. 2023 Dec 20;25(1):104. doi: 10.3390/ijms25010104.
Association of Single-Nucleotide Polymorphisms in Capecitabine Bioactivation Pathway with Adjuvant Therapy Safety in Colorectal Cancer Patients. Cura Y, Sánchez-Martín A, Márquez-Pete N, González-Flores E, Martínez-Martínez F, Pérez-Ramírez C, Jiménez-Morales A. Pharmaceutics. 2023 Oct 28;15(11):2548. doi: 10.3390/pharmaceutics15112548.
ABCC1, ABCG2 and FOXP3: Predictive Biomarkers of Toxicity from Methotrexate Treatment in Patients Diagnosed with Moderate-to-Severe Psoriasis. Membrive-Jiménez C, Vieira-Maroun S, Márquez-Pete N, Cura Y, Pérez-Ramírez C, Tercedor-Sánchez J, Jiménez-Morales A, Ramírez-Tortosa MDC. Biomedicines. 2023 Sep 19;11(9):2567. doi: 10.3390/biomedicines11092567.
Single Nucleotide Polymorphisms in the Vitamin D Metabolic Pathway as Survival Biomarkers in Colorectal Cancer. Pérez-Durán C, Márquez-Pete N, Gálvez-Navas JM, Cura Y, Rojo-Tolosa S, Pineda-Lancheros LE, Ramírez-Tortosa M, García-Collado C, Maldonado-Montoro MDM, Villar-Del-Moral JM, Pérez-Ramírez C, Jiménez-Morales A. Cancers (Basel). 2023 Aug 12;15(16):4077. doi: 10.3390/cancers15164077.
Influence of Single-Nucleotide Polymorphisms on Clinical Outcomes of Capecitabine-Based Chemotherapy in Colorectal Cancer Patients: A Systematic Review. Cura Y, Pérez-Ramírez C, Sánchez-Martín A, Membrive-Jimenez C, Valverde-Merino MI, González-Flores E, Morales AJ. Cancers (Basel). 2023 Mar 17;15(6):1821. doi: 10.3390/cancers15061821.
Genetic polymorphisms on the effectiveness or safety of breast cancer treatment: Clinical relevance and future perspectives. Cura Y, Pérez Ramírez C, Sánchez Martín A, Martínez Martínez F, Calleja Hernández MÁ, Ramírez Tortosa MDC, Jiménez Morales A. Mutat Res Rev Mutat Res. 2021 Jul-Dec;788:108391. doi: 10.1016/j.mrrev.2021.108391..
Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells. Asenjo HG, Alcazar-Fabra M, Espinosa-Martínez M, Lopez-Onieva L, Gallardo A, Dimitrova E, Feldmann A, Pachano T, Martorell-Marugán J, Carmona-Sáez P, Sanchez-Pozo A, Rada-Iglesias Á, Klose RJ, Landeira D. Nat Commun. 2023 Jan 12;14(1):180. doi: 10.1038/s41467-023-35859-9.
Polycomb regulation is coupled to cell cycle transition in pluripotent stem cells. Asenjo HG, Gallardo A, López-Onieva L, Tejada I, Martorell-Marugán J, Carmona-Sáez P, Landeira D. Sci Adv. 2020 Mar 4;6(10):eaay4768. doi: 10.1126/sciadv.aay4768.
The molecular clock protein Bmal1 regulates cell differentiation in mouse embryonic stem cells. Gallardo A, Molina A, Asenjo HG, Martorell-Marugán J, Montes R, Ramos-Mejia V, Sanchez-Pozo A, Carmona-Sáez P, Lopez-Onieva L, Landeira D. Life Sci Alliance. 2020 Apr 13;3(5):e201900535. doi: 10.26508/lsa.201900535.
EZH2 endorses cell plasticity to non-small cell lung cancer cells facilitating mesenchymal to epithelial transition and tumour colonization. Gallardo A, Molina A, Asenjo HG, Lopez-Onieva L, Martorell-Marugán J, Espinosa-Martinez M, Griñan-Lison C, Alvarez-Perez JC, Cara FE, Navarro-Marchal SA, Carmona-Sáez P, Medina PP, Marchal JA, Granados-Principal S, Sánchez-Pozo A, Landeira D. Oncogene. 2022 Jul;41(28):3611-3624. doi: 10.1038/s41388-022-02375-x.
The pediatric leukemia oncoprotein NUP98-KDM5A induces genomic instability that may facilitate malignant transformation. Domingo-Reinés J, Montes R, Garcia-Moreno A, Gallardo A, Sanchez-Manas JM, Ellson I, Lamolda M, Calabro C, López-Escamez JA, Catalina P, Carmona-Sáez P, Real PJ, Landeira D, Ramos-Mejia V. Cell Death Dis. 2023 Jun 10;14(6):357. doi: 10.1038/s41419-023-05870-5.
EZH2 represses mesenchymal genes and upholds the epithelial state of breast carcinoma cells. Gallardo A, López-Onieva L, Belmonte-Reche E, Fernández-Rengel I, Serrano-Prados A, Molina A, Sánchez-Pozo A, Landeira D. Cell Death Dis. 2024 Aug 22;15(8):609. doi: 10.1038/s41419-024-07011-y.
Epigenome wide association study in peripheral blood of pregnant women identifies potential metabolic pathways related to gestational diabetes. Linares-Pineda TM, Peña-Montero N, Gutiérrez-Repiso C, Lima-Rubio F, Sánchez-Pozo A, Tinahones FJ, Molina-Vega M, Picón-César MJ, Morcillo S. Epigenetics. 2023 Dec;18(1):2211369. doi: 10.1080/15592294.2023.2211369.
Gene polymorphisms as predictors of response to biological therapies in psoriasis patients. Linares-Pineda TM, Cañadas-Garre M, Sánchez-Pozo A, Calleja-Hernández MÁ. Pharmacol Res. 2016 Nov;113(Pt A):71-80. doi: 10.1016/j.phrs.2016.07.020.
Epigenetic changes in the metabolically healthy obese: A case-control versus a prospective study. Linares-Pineda TM, Boughanem H, Gutiérrez-Repiso C, Macías-González M, Andrés-León E, Rojo-Martínez G, Valdés S, Tinahones FJ, Morcillo S. Eur J Clin Invest. 2022 Aug;52(8):e13783. doi: 10.1111/eci.13783.
Impact of the Gestational Diabetes Diagnostic Criteria during the Pandemic: An Observational Study. Molina-Vega M, Gutiérrez-Repiso C, Lima-Rubio F, Suárez-Arana M, Linares-Pineda TM, Cobos Díaz A, Tinahones FJ, Morcillo S, Picón-César MJ. J Clin Med. 2021 Oct 24;10(21):4904. doi: 10.3390/jcm10214904.
Changes in Oxidative Stress and Intestinal Permeability during Pregnancy in Women with Gestational Diabetes Mellitus Treated with Metformin or Insulin and Healthy Controls: A Randomized Controlled Trial. Fernández-Valero A, Peña-Montero N, Lima-Rubio F, Gutiérrez-Repiso C, Linares-Pineda TM, Picón-César MJ, Sancho-Marín R, Tinahones FJ, Morcillo S, Molina-Vega M. Antioxidants (Basel). 2023 Nov 8;12(11):1981. doi: 10.3390/antiox12111981.
Insulin Requirement for Gestational Diabetes Control Is Related to Higher Vitamin D Levels up to 1 Year Postpartum: A Prospective Cohort Study. Molina-Vega M, Picón-César MJ, Lima-Rubio F, Gutiérrez-Repiso C, Linares-Pineda TM, Suárez-Arana M, Fernández-Ramos AM, Tinahones FJ, Morcillo S. Antioxidants (Basel). 2022 Nov 11;11(11):2230. doi: 10.3390/antiox11112230.
Higher β cell death in pregnant women, measured by DNA methylation patterns of cell-free DNA, compared to new-onset type 1 and type 2 diabetes subjects: a cross-sectional study. Linares-Pineda TM, Gutiérrez-Repiso C, Peña-Montero N, Molina-Vega M, Rubio FL, Arana MS, Tinahones FJ, Picón-César MJ, Morcillo S. Diabetol Metab Syndr. 2023 Jun 1;15(1):115. doi: 10.1186/s13098-023-01096-9.
Epigenetic Biomarkers of Transition from Metabolically Healthy Obesity to Metabolically Unhealthy Obesity Phenotype: A Prospective Study. Gutiérrez-Repiso C, Linares-Pineda TM, Gonzalez-Jimenez A, Aguilar-Lineros F, Valdés S, Soriguer F, Rojo-Martínez G, Tinahones FJ, Morcillo S. Int J Mol Sci. 2021 Sep 27;22(19):10417. doi: 10.3390/ijms221910417.
Crossiellidines A-F, Unprecedented Pyrazine-Alkylguanidine Metabolites with Broad-Spectrum Antibacterial Activity from Crossiella sp. Ortiz-López FJ, Oves-Costales D, Carretero-Molina D, Martín J, Díaz C, de la Cruz M, Román-Hurtado F, Álvarez-Arévalo M, Jørgensen TS, Reyes F, Weber T, Genilloud O. Org Lett. 2023 May 19;25(19):3502-3507. doi: 10.1021/acs.orglett.3c01088.
Euglenatides, Potent Antiproliferative Cyclic Peptides Isolated from the Freshwater Photosynthetic Microalga Euglena gracilis. Aldholmi M, Ahmad R, Carretero-Molina D, Pérez-Victoria I, Martín J, Reyes F, Genilloud O, Gourbeyre L, Gefflaut T, Carlsson H, Maklakov A, O'Neill E, Field RA, Wilkinson B, O'Connell M, Ganesan A. Angew Chem Int Ed Engl. 2022 Jun 7;61(23):e202203175. doi: 10.1002/anie.202203175.
Pentaminomycins F and G, Nonribosomal Peptides Containing 2-Pyridylalanine. Carretero-Molina D, Ortiz-López FJ, Martín J, González I, Sánchez-Hidalgo M, Román-Hurtado F, Díaz C, de la Cruz M, Genilloud O, Reyes F. J Nat Prod. 2021 Apr 23;84(4):1127-1134. doi: 10.1021/acs.jnatprod.0c01199.
Cacaoidin, First Member of the New Lanthidin RiPP Family. Ortiz-López FJ, Carretero-Molina D, Sánchez-Hidalgo M, Martín J, González I, Román-Hurtado F, de la Cruz M, García-Fernández S, Reyes F, Deisinger JP, Müller A, Schneider T, Genilloud O. Angew Chem Int Ed Engl. 2020 Jul 27;59(31):12654-12658. doi: 10.1002/anie.202005187.
New Napyradiomycin Analogues from Streptomyces sp. Strain CA-271078. Carretero-Molina D, Ortiz-López FJ, Martín J, Oves-Costales D, Díaz C, de la Cruz M, Cautain B, Vicente F, Genilloud O, Reyes F. Mar Drugs. 2019 Dec 26;18(1):22. doi: 10.3390/md18010022.
Complete Genome Sequence of Amycolatopsis sp. CA-230715, Encoding a 35-Module Type I Polyketide Synthase. Jørgensen TS, Gren T, Oves-Costales D, Ortiz-López FJ, Carretero-Molina D, González I, Blin K, Genilloud O, Weber T. Microbiol Resour Announc. 2021 Sep 23;10(38):e0080521. doi: 10.1128/MRA.00805-21.
One Pathway, Two Cyclic Non-Ribosomal Pentapeptides: Heterologous Expression of BE-18257 Antibiotics and Pentaminomycins from Streptomyces cacaoi CA-170360. Román-Hurtado F, Sánchez-Hidalgo M, Martín J, Ortiz-López FJ, Carretero-Molina D, Reyes F, Genilloud O. Microorganisms. 2021 Jan 8;9(1):135. doi: 10.3390/microorganisms9010135.
Activation and Identification of a Griseusin Cluster in Streptomyces sp. CA-256286 by Employing Transcriptional Regulators and Multi-Omics Methods. Beck C, Gren T, Ortiz-López FJ, Jørgensen TS, Carretero-Molina D, Martín Serrano J, Tormo JR, Oves-Costales D, Kontou EE, Mohite OS, Mingyar E, Stegmann E, Genilloud O, Weber T. Molecules. 2021 Oct 30;26(21):6580. doi: 10.3390/molecules26216580.
Exchangeable Self-Assembled Lanthanide Antennas for PLIM Microscopy. Ruiz-Arias A, Fueyo-González F, Izquierdo-García C, Navarro A, Gutiérrez-Rodríguez M, Herranz R, Burgio C, Reinoso A, Cuerva JM, Orte A, González-Vera JA. Angew Chem Int Ed Engl. 2024 Feb 5;63(6):e202314595. doi: 10.1002/anie.202314595.
Multiple pathways for lanthanide sensitization in self-assembled aqueous complexes. Navarro A, Ruiz-Arias A, Fueyo-González F, Izquierdo-García C, Peña-Ruiz T, Gutiérrez-Rodríguez M, Herranz R, Cuerva JM, González-Vera JA, Orte A. Spectrochim Acta A Mol Biomol Spectrosc. 2024 Dec 15;323:124926. doi: 10.1016/j.saa.2024.124926.
Apoferritin Protein Amyloid Fibrils with Tunable Chirality and Polymorphism. Jurado R, Adamcik J, López-Haro M, González-Vera JA, Ruiz-Arias Á, Sánchez-Ferrer A, Cuesta R, Domínguez-Vera JM, Calvino JJ, Orte A, Mezzenga R, Gálvez N. J Am Chem Soc. 2019 Jan 30;141(4):1606-1613. doi: 10.1021/jacs.8b11418.
Environment-Sensitive Probes for Illuminating Amyloid Aggregation In Vitro and in Zebrafish. Fueyo-González F, González-Vera JA, Alkorta I, Infantes L, Jimeno ML, Aranda P, Acuña-Castroviejo D, Ruiz-Arias A, Orte A, Herranz R. ACS Sens. 2020 Sep 25;5(9):2792-2799. doi: 10.1021/acssensors.0c00587.
Seeding and Growth of β-Amyloid Aggregates upon Interaction with Neuronal Cell Membranes. Ruiz-Arias Á, Paredes JM, Di Biase C, Cuerva JM, Giron MD, Salto R, González-Vera JA, Orte A. Int J Mol Sci. 2020 Jul 16;21(14):5035. doi: 10.3390/ijms21145035.
Dopamine-loaded chitosan-coated solid lipid nanoparticles as a promise nanocarriers to the CNS. Ortega Martínez E, Morales Hernández ME, Castillo-González J, González-Rey E, Ruiz Martínez MA. Neuropharmacology. 2024 May 15;249:109871. doi: 10.1016/j.neuropharm.2024.109871.
The Relevance of Monoclonal Antibodies in the Treatment of COVID-19. Torrente-López A, Hermosilla J, Navas N, Cuadros-Rodríguez L, Cabeza J, Salmerón-García A. Vaccines (Basel). 2021 May 26;9(6):557. doi: 10.3390/vaccines9060557.
Use of subcutaneous tocilizumab to prepare intravenous solutions for COVID-19 emergency shortage: Comparative analytical study of physicochemical quality attributes. Navas N, Hermosilla J, Torrente-López A, Hernández-Jiménez J, Cabeza J, Pérez-Robles R, Salmerón-García A. J Pharm Anal. 2020 Dec;10(6):532-545. doi: 10.1016/j.jpha.2020.06.003.
Comprehensive Analysis of Nivolumab, A Therapeutic Anti-Pd-1 Monoclonal Antibody: Impact of Handling and Stress. Torrente-López A, Hermosilla J, Salmerón-García A, Cabeza J, Navas N. Pharmaceutics. 2022 Mar 23;14(4):692. doi: 10.3390/pharmaceutics14040692.
Comprehensive Analysis of Cetuximab Critical Quality Attributes: Impact of Handling on Antigen-Antibody Binding. Torres-García A, Torrente-López A, Hermosilla J, Hernández A, Salmerón-García A, Cabeza J, Navas N. Pharmaceutics. 2024 Sep 19;16(9):1222. doi: 10.3390/pharmaceutics16091222.
Comprehensive physicochemical and functional analysis of pembrolizumab based on controlled degradation studies: Impact on antigen-antibody binding. Torrente-López A, Hermosilla J, Salmerón-García A, Cabeza J, Ruiz-Martínez A, Navas N. Eur J Pharm Biopharm. 2024 Jan;194:131-147. doi: 10.1016/j.ejpb.2023.12.005.
Comprehensive physicochemical characterization of a peptide-based medicine: Teduglutide (Revestive®) structural description and stress testing. Pérez-Robles R, Salmerón-García A, Hermosilla J, Torrente-López A, Clemente-Bautista S, Jiménez-Lozano I, Cabañas-Poy MJ, Cabeza J, Navas N. Eur J Pharm Biopharm. 2023 Mar;184:103-115. doi: 10.1016/j.ejpb.2023.01.001.
Influence of Genetic Polymorphisms on Response to Biologics in Moderate-to-Severe Psoriasis. Membrive Jiménez C, Pérez Ramírez C, Sánchez Martín A, Vieira Maroun S, Arias Santiago SA, Ramírez Tortosa MDC, Jiménez Morales A. J Pers Med. 2021 Apr 12;11(4):293. doi: 10.3390/jpm11040293.
Clinical Application of Pharmacogenetic Markers in the Treatment of Dermatologic Pathologies. Membrive Jiménez C, Pérez Ramírez C, Sánchez Martín A, Vieira Maroun S, Arias Santiago S, Ramírez Tortosa MC, Jiménez Morales A. Pharmaceuticals (Basel). 2021 Sep 6;14(9):905. doi: 10.3390/ph14090905.
Effect of genetic polymorphisms on therapeutic response in multiple sclerosis relapsing-remitting patients treated with interferon-beta. Martínez-Aguilar L, Pérez-Ramírez C, Maldonado-Montoro MDM, Carrasco-Campos MI, Membrive-Jiménez C, Martínez-Martínez F, García-Collado C, Calleja-Hernández MÁ, Ramírez-Tortosa MC, Jiménez-Morales A. Mutat Res Rev Mutat Res. 2020 Jul-Sep;785:108322. doi: 10.1016/j.mrrev.2020.108322.
Insights into the Window of Opportunity and Outcome Measures in Patients with Moderate to Severe Hidradenitis Suppurativa Treated with Secukinumab: A Real-World Study. Haselgruber S, Fernández-Crehuet-Serrano P, Fernández-Ballesteros MD, Padial-Gómez A, Hernández-Rodríguez JC, Ortiz-Álvarez J, Navarro-Guillamón P, Membrive-Jiménez C, Cuenca-Barrales C, Molina-Leyva A. Dermatol Ther (Heidelb). 2024 Jul;14(7):1875-1890. doi: 10.1007/s13555-024-01209-w.
Impact of Functional Polymorphisms on Drug Survival of Biological Therapies in Patients with Moderate-to-Severe Psoriasis. Membrive-Jiménez C, Pérez-Ramírez C, Arias-Santiago S, Richetta AG, Ottini L, Pineda-Lancheros LE, Ramírez-Tortosa MDC, Jiménez-Morales A. Int J Mol Sci. 2023 May 12;24(10):8703. doi: 10.3390/ijms24108703.
Safety and effectiveness of bDMARDs during pregnancy in patients with rheumatic diseases: Real-world data from the BIOBADASER registry. Membrive-Jiménez C, Sánchez-Piedra C, Martínez-González O, García-González J, Expósito-Pérez L, Bohórquez-Heras C, Campos-Fernández C, Sanchez-Alonso F, Cáliz-Cáliz R, Castrejón-Fernández I. Reumatol Clin (Engl Ed). 2023 Nov;19(9):500-506. doi: 10.1016/j.reumae.2023.02.005
ABCC1, ABCG2 and FOXP3: Predictive Biomarkers of Toxicity from Methotrexate Treatment in Patients Diagnosed with Moderate-to-Severe Psoriasis. Membrive-Jiménez C, Vieira-Maroun S, Márquez-Pete N, Cura Y, Pérez-Ramírez C, Tercedor-Sánchez J, Jiménez-Morales A, Ramírez-Tortosa MDC. Biomedicines. 2023 Sep 19;11(9):2567. doi: 10.3390/biomedicines11092567.
Pharmacist-led antimicrobial stewardship programme in a small hospital without infectious diseases physicians. Cantudo-Cuenca MR, Jiménez-Morales A, Martínez-de la Plata JE. Sci Rep. 2022 Jun 9;12(1):9501. doi: 10.1038/s41598-022-13246-6.
Pharmaceutical recommendations for therapeutic appropriateness in patients with multiple sclerosis. Suárez MDMS, Roldán AM, Cuenca MRC, Morales AJ. Farm Hosp. 2024 Sep-Oct;48(5):T230-T233. doi: 10.1016/j.farma.2024.05.002
The RNA-binding protein RBP33 dampens non-productive transcription in trypanosomes. Gómez-Liñán C, Gómez-Díaz E, Ceballos-Pérez G, Fernández-Moya SM, Estévez AM. Nucleic Acids Res. 2022 Nov 28;50(21):12251-12265. doi: 10.1093/nar/gkac1123.
Identification of novel anti-amoebic pharmacophores from kinase inhibitor chemotypes. Ferrins L, Buskes MJ, Kapteyn MM, Engels HN, Enos SE, Lu C, Klug DM, Singh B, Quotadamo A, Bachovchin K, Tear WF, Spaulding AE, Forbes KC, Bag S, Rivers M, LeBlanc C, Burchfield E, Armand JR, Diaz-Gonzalez R, Ceballos-Perez G, García-Hernández R, Pérez-Moreno G, Bosch-Navarrete C, Ruiz-Pérez LM, Gamarro F, González-Pacanowska D, Navarro M, Mensa-Wilmot K, Pollastri MP, Kyle DE, Rice CA. Front Microbiol. 2023 May 10;14:1149145. doi: 10.3389/fmicb.2023.1149145.
Lead Optimization of 3,5-Disubstituted-7-Azaindoles for the Treatment of Human African Trypanosomiasis. Klug DM, Mavrogiannaki EM, Forbes KC, Silva L, Diaz-Gonzalez R, Pérez-Moreno G, Ceballos-Pérez G, Garcia-Hernández R, Bosch-Navarrete C, Cordón-Obras C, Gómez-Liñán C, Saura A, Momper JD, Martinez-Martinez MS, Manzano P, Syed A, El-Sakkary N, Caffrey CR, Gamarro F, Ruiz-Perez LM, Gonzalez Pacanowska D, Ferrins L, Navarro M, Pollastri MP. J Med Chem. 2021 Jul 8;64(13):9404-9430. doi: 10.1021/acs.jmedchem.1c00674. 5 Structure-property studies of an imidazoquinoline chemotype with antitrypanosomal activity. Klug DM, Diaz-Gonzalez R, DeLano TJ, Mavrogiannaki EM, Buskes MJ, Dalton RM, Fisher JK, Schneider KM, Hilborne V, Fritsche MG, Simpson QJ, Tear WF, Devine WG, Pérez-Moreno G, Ceballos-Pérez G, García-Hernández R, Bosch-Navarrete C, Ruiz-Pérez LM, Gamarro F, González-Pacanowska D, Martinez-Martinez MS, Manzano-Chinchon P, Navarro M, Pollastri MP, Ferrins L. RSC Med Chem. 2020 Jul 10;11(8):950-959. doi: 10.1039/d0md00103a.
An RNA-binding protein complex regulates the purine-dependent expression of a nucleobase transporter in trypanosomes. Rico-Jiménez M, Ceballos-Pérez G, Gómez-Liñán C, Estévez AM. Nucleic Acids Res. 2021 Apr 19;49(7):3814-3825. doi: 10.1093/nar/gkab181.
Medicinal Chemistry Optimization of a Diaminopurine Chemotype: Toward a Lead for Trypanosoma brucei Inhibitors. Singh B, Diaz-Gonzalez R, Ceballos-Perez G, Rojas-Barros DI, Gunaganti N, Gillingwater K, Martinez-Martinez MS, Manzano P, Navarro M, Pollastri MP. J Med Chem. 2020 Sep 10;63(17):9912-9927. doi: 10.1021/acs.jmedchem.0c01017.
Selectivity and Physicochemical Optimization of Repurposed Pyrazolo[1,5-b]pyridazines for the Treatment of Human African Trypanosomiasis. Tear WF, Bag S, Diaz-Gonzalez R, Ceballos-Pérez G, Rojas-Barros DI, Cordon-Obras C, Pérez-Moreno G, García-Hernández R, Martinez-Martinez MS, Ruiz-Perez LM, Gamarro F, Gonzalez Pacanowska D, Caffrey CR, Ferrins L, Manzano P, Navarro M, Pollastri MP. J Med Chem. 2020 Jan 23;63(2):756-783. doi: 10.1021/acs.jmedchem.9b01741.
Role of the RNA-binding protein ZC3H41 in the regulation of ribosomal protein messenger RNAs in trypanosomes. Ceballos-Pérez G, Rico-Jiménez M, Gómez-Liñán C, Estévez AM. Parasit Vectors. 2023 Mar 31;16(1):118. doi: 10.1186/s13071-023-05728-x.
The AMPKα1 Pathway Positively Regulates the Developmental Transition from Proliferation to Quiescence in Trypanosoma brucei. Saldivia M, Ceballos-Pérez G, Bart JM, Navarro M. Cell Rep. 2016 Oct 11;17(3):660-670. doi: 10.1016/j.celrep.2016.09.041.
Novel 1,2-dihydroquinazolin-2-ones: Design, synthesis, and biological evaluation against Trypanosoma brucei. Pham T, Walden M, Butler C, Diaz-Gonzalez R, Pérez-Moreno G, Ceballos-Pérez G, Gomez-Pérez V, García-Hernández R, Zecca H, Krakoff E, Kopec B, Ichire O, Mackenzie C, Pitot M, Ruiz LM, Gamarro F, González-Pacanowska D, Navarro M, Dounay AB. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3629-3635. doi: 10.1016/j.bmcl.2017.07.032.
Pharmacophore Identification and Structure-Activity Relationship Analysis of a Series of Substituted Azaindoles as Inhibitors of Trypanosoma brucei. Ferrins L, Diaz R, Cordon-Obras C, Rojas-Barros D, Quotadamo A, Oehme DP, Ceballos-Pérez G, Swaminathan U, Pérez-Moreno G, Bosch-Navarrete C, García-Hernández R, Gomez-Liñan C, Saura A, Ruiz-Perez LM, Gamarro F, Martinez-Martinez MS, Manzano P, González-Pacanowska D, Navarro M, Pollastri MP. J Med Chem. 2024 Aug 22;67(16):13985-14006. doi: 10.1021/acs.jmedchem.4c00785.
Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents. Klug DM, Diaz-Gonzalez R, Pérez-Moreno G, Ceballos-Pérez G, García-Hernández R, Gomez-Pérez V, Ruiz-Pérez LM, Rojas-Barros DI, Gamarro F, González-Pacanowska D, Martínez-Martínez MS, Manzano P, Ferrins L, Caffrey CR, Navarro M, Pollastri MP. PLoS Negl Trop Dis. 2019 Feb 8;13(2):e0007129. doi: 10.1371/journal.pntd.0007129.
Association between Single Nucleotide Polymorphisms Related to Vitamin D Metabolism and the Risk of Developing Asthma. Rojo-Tolosa S, Pineda-Lancheros LE, Gálvez-Navas JM, Sánchez-Martínez JA, González-Gutiérrez MV, Fernández-Alonso A, Morales-García C, Jiménez-Morales A, Pérez-Ramírez C. Nutrients. 2023 Feb 5;15(4):823. doi: 10.3390/nu15040823
Influence of Genetics on the Response to Omalizumab in Patients with Severe Uncontrolled Asthma with an Allergic Phenotype. Rojo-Tolosa S, Sánchez-Martínez JA, Pineda-Lancheros LE, Gálvez-Navas JM, González-Gutiérrez MV, Jiménez-Gálvez G, Pérez-Ramírez C, Morales-García C, Jiménez-Morales A. Int J Mol Sci. 2023 Apr 10;24(8):7029. doi: 10.3390/ijms24087029.
Impact of Omalizumab in Patients with Severe Uncontrolled Asthma and Possible Predictive Biomarkers of Response: A Real-Life Study. Rojo-Tolosa S, González-Gutiérrez MV, Sánchez-Martínez JA, Jiménez-Gálvez G, Pineda-Lancheros LE, Gálvez-Navas JM, Jiménez-Morales A, Pérez-Ramírez C, Morales-García C. Pharmaceutics. 2023 Feb 4;15(2):523. doi: 10.3390/pharmaceutics15020523.
Single Nucleotide Polymorphisms in the Vitamin D Metabolic Pathway and Their Relationship with High Blood Pressure Risk. Rojo-Tolosa S, Márquez-Pete N, Gálvez-Navas JM, Pineda-Lancheros LE, Fernández-Alonso A, Membrive-Jiménez C, Ramírez-Tortosa MC, Pérez-Ramírez C, Jiménez-Morales A. Int J Mol Sci. 2023 Mar 22;24(6):5974. doi: 10.3390/ijms24065974.
Impact of Anti-IL5 Therapies on Patients with Severe Uncontrolled Asthma and Possible Predictive Biomarkers of Response: A Real-Life Study. Rojo-Tolosa S, González-Gutiérrez MV, Jiménez-Gálvez G, Sánchez-Martínez JA, Pineda-Lancheros LE, Gálvez-Navas JM, Jiménez-Morales A, Pérez-Ramírez C, Morales-García C. Int J Mol Sci. 2023 Jan 19;24(3):2011. doi: 10.3390/ijms24032011.
SingleNucleotide Polymorphisms as Biomarkers of Mepolizumab and Benralizumab Treatment Response in Severe Eosinophilic Asthma. Rojo-Tolosa S, Sánchez-Martínez JA, Caballero-Vázquez A, Pineda-Lancheros LE, González-Gutiérrez MV, Pérez-Ramírez C, Jiménez-Morales A, Morales-García C. Int J Mol Sci. 2024 Jul 26;25(15):8139. doi: 10.3390/ijms25158139.
New Red-Emitting Chloride-Sensitive Fluorescent Protein with Biological Uses. Salto R, Giron MD, Puente-Muñoz V, Vilchez JD, Espinar-Barranco L, Valverde-Pozo J, Arosio D, Paredes JM. ACS Sens. 2021 Jul 23;6(7):2563-2573. doi: 10.1021/acssensors.1c00094.
New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action. Luque-Navarro PM, Carrasco-Jiménez MP, Goracci L, Paredes JM, Espinar-Barranco L, Valverde-Pozo J, Torretta A, Parisini E, Mariotto E, Marchioro C, Laso A, Marco C, Viola G, Lanari D, López Cara LC. Eur J Med Chem. 2023 Jan 15;246:115003. doi: 10.1016/j.ejmech.2022.115003.
Ratiometric Two-Photon Near-Infrared Probe to Detect DPP IV in Human Plasma, Living Cells, Human Tissues, and Whole Organisms Using Zebrafish. Valverde-Pozo J, Paredes JM, Widmann TJ, Griñan-Lison C, Ceccarelli G, Gioiello A, Garcia-Rubiño ME, Marchal JA, Alvarez-Pez JM, Talavera EM. ACS Sens. 2023 Mar 24;8(3):1064-1075. doi: 10.1021/acssensors.2c02025.
Advanced Imaging Methodology in Bacterial Biofilms with a Fluorescent Enzymatic Sensor for pepN Activity. Valverde-Pozo J, Paredes JM, García-Rubiño ME, Girón MD, Salto R, Alvarez-Pez JM, Talavera EM. Biosensors (Basel). 2024 Sep 3;14(9):424. doi: 10.3390/bios14090424.
Polymorphisms in VDR, CYP27B1, CYP2R1, GC and CYP24A1 Genes as Biomarkers of Survival in Non-Small Cell Lung Cancer: A Systematic Review. Pineda-Lancheros LE, Gálvez-Navas JM, Rojo-Tolosa S, Membrive-Jiménez C, Valverde-Merino MI, Martínez-Martínez F, Sánchez-Martín A, Ramírez-Tortosa M, Pérez-Ramírez C, Jiménez-Morales A. Nutrients. 2023 Mar 21;15(6):1525. doi: 10.3390/nu15061525.
Association between polymorphisms in the vitamin D receptor and susceptibility to multiple sclerosis. Cancela Díez B, Pérez-Ramírez C, Maldonado-Montoro MDM, Carrasco-Campos MI, Sánchez Martín A, Pineda Lancheros LE, Martínez-Martínez F, Calleja-Hernández MÁ, Ramírez-Tortosa MC, Jiménez-Morales A. Pharmacogenet Genomics. 2021 Feb 1;31(2):40-47. doi: 10.1097/FPC.0000000000000420.
Effect of Single Nucleotide Polymorphisms in the Vitamin D Metabolic Pathway on Susceptibility to Non-Small-Cell Lung Cancer. Pineda Lancheros LE, Rojo Tolosa S, Gálvez Navas JM, Martínez Martínez F, Sánchez Martín A, Jiménez Morales A, Pérez Ramírez C. Nutrients. 2022 Nov 4;14(21):4668. doi: 10.3390/nu14214668.
Impact of Genetic Polymorphisms on the Metabolic Pathway of Vitamin D and Survival in Non-Small Cell Lung Cancer. Pineda Lancheros LE, Pérez Ramírez C, Sánchez Martín A, Gálvez Navas JM, Martínez Martínez F, Ramírez Tortosa MDC, Jiménez Morales A. Nutrients. 2021 Oct 25;13(11):3783. doi: 10.3390/nu13113783.
An effective polymeric nanocarrier that allows for active targeting and selective drug delivery in cell coculture systems. Cano-Cortes MV, Altea-Manzano P, Laz-Ruiz JA, Unciti-Broceta JD, Lopez-Delgado FJ, Espejo-Roman JM, Diaz-Mochon JJ, Sanchez-Martin RM. Nanoscale. 2021 Feb 18;13(6):3500-3511. doi: 10.1039/d0nr07145e.
Selective Anticancer Therapy Based on a HA-CD44 Interaction Inhibitor Loaded on Polymeric Nanoparticles. Espejo-Román JM, Rubio-Ruiz B, Cano-Cortés V, Cruz-López O, Gonzalez-Resines S, Domene C, Conejo-García A, Sánchez-Martín RM. Pharmaceutics. 2022 Apr 4;14(4):788. doi: 10.3390/pharmaceutics14040788.
N-aryltetrahydroisoquinoline derivatives as HA-CD44 interaction inhibitors: Design, synthesis, computational studies, and antitumor effect. Espejo-Román JM, Rubio-Ruiz B, Chayah-Ghaddab M, Vega-Gutierrez C, García-García G, Muguruza-Montero A, Domene C, Sánchez-Martín RM, Cruz-López O, Conejo-García A. Eur J Med Chem. 2023 Oct 5;258:115570. doi: 10.1016/j.ejmech.2023.115570.
* David Blánquez Martínez Genetic Polymorphisms Affecting Ranibizumab Response in High Myopia Patients. Blánquez-Martínez D, Díaz-Villamarín X, Antúnez-Rodríguez A, Pozo-Agundo A, Muñoz-Ávila JI, Martínez-González LJ, Dávila-Fajardo CL. Pharmaceutics. 2021 Nov 20;13(11):1973. doi: 10.3390/pharmaceutics13111973..
Genetic Polymorphisms in VEGFR Coding Genes (FLT1/KDR) on Ranibizumab Response in High Myopia and Choroidal Neovascularization Patients. Blánquez-Martínez D, Díaz-Villamarín X, García-Rodríguez S, Antúnez-Rodríguez A, Pozo-Agundo A, Martínez-González LJ, Muñoz-Ávila JI, Dávila-Fajardo CL. Pharmaceutics. 2022 Jul 26;14(8):1555. doi: 10.3390/pharmaceutics14081555..
Genetic Variants Affecting Anti-VEGF Drug Response in Polypoidal Choroidal Vasculopathy Patients: A Systematic Review and Meta-Analysis. Díaz-Villamarín X, Blánquez-Martínez D, Pozo-Agundo A, Pérez-Gutiérrez AM, Muñoz-Ávila JI, Antúnez-Rodríguez A, Fernández-Gómez AE, García-Navas P, Martínez-González LJ, Dávila-Fajardo CL. Genes (Basel). 2020 Nov 12;11(11):1335. doi: 10.3390/genes11111335.
Ricardo García Fumero Dalbavancin is a novel antimicrobial against Gram-positive pathogens: clinical experience beyond labelled indications. Núñez-Núñez M PharmD, MsC, Casas-Hidalgo I, García-Fumero R, Vallejo-Rodríguez I, Anguita-Santos F, Hernández-Quero J, Cabeza-Barrera J, Ruiz-Sancho A. Eur J Hosp Pharm. 2020 Sep;27(5):310-312. doi: 10.1136/ejhpharm-2018-001711.
Clinical Outcomes of First-line Therapies for Advanced Non-Small Cell Lung Cancer: A Systematic Review of Trials Published Between 2010 and 2020. García-Fumero R, Fernández-López C, Calleja-Hernández MÁ, Expósito-Ruiz M, Espín J, Expósito-Hernández J. Am J Clin Oncol. 2023 Oct 1;46(10):433-438. doi: 10.1097/COC.0000000000001031
Analyzing the clinical benefit of newer therapies for advanced or metastatic non-small-cell lung cancer: application of the ESMO-magnitude of clinical benefit scale v1.1. García-Fumero R, Fernández-López C, Calleja-Hernández MÁ, Expósito-Hernández J. Acta Oncol. 2021 Sep;60(9):1225-1232. doi: 10.1080/0284186X.2021.1942546.
Dynamic Excimer (DYNEX) Imaging of Lipid Droplets. Gonzalez-Garcia MC, Salto-Giron C, Herrero-Foncubierta P, Peña-Ruiz T, Giron-Gonzalez MD, Salto-Gonzalez R, Perez-Lara A, Navarro A, Garcia-Fernandez E, Orte A. ACS Sens. 2021 Oct 22;6(10):3632-3639. doi: 10.1021/acssensors.1c01206.
Coupled Excited-State Dynamics in N-Substituted 2-Methoxy-9-Acridones. Gonzalez-Garcia MC, Herrero-Foncubierta P, Castro S, Resa S, Alvarez-Pez JM, Miguel D, Cuerva JM, Garcia-Fernandez E, Orte A. Front Chem. 2019 Mar 12;7:129. doi: 10.3389/fchem.2019.00129.
Optical Binding-Driven Micropatterning and Photosculpting with Silver Nanorods. Gonzalez-Garcia MC, Garcia-Fernandez E, Hueso JL, Paulo PMR, Orte A. Small Methods. 2023 Sep;7(9):e2300076. doi: 10.1002/smtd.202300076.
Building Accurate Intracellular Polarity Maps through Multiparametric Microscopy. Gonzalez-Garcia MC, Herrero-Foncubierta P, Garcia-Fernandez E, Orte A. Methods Protoc. 2020 Nov 11;3(4):78. doi: 10.3390/mps3040078..
Chimeric Drug Design with a Noncharged Carrier for Mitochondrial Delivery. Ripoll C, Herrero-Foncubierta P, Puente-Muñoz V, Gonzalez-Garcia MC, Miguel D, Resa S, Paredes JM, Ruedas-Rama MJ, Garcia-Fernandez E, Roldan M, Rocha S, De Keersmaecker H, Hofkens J, Martin M, Cuerva JM, Orte A. Pharmaceutics. 2021 Feb 12;13(2):254. doi: 10.3390/pharmaceutics13020254.
A multicomponent reaction platform towards multimodal near-infrared BODIPY dyes for STED and fluorescence lifetime imaging. Fernandez A, Kielland N, Makda A, Carragher NO, González-García MC, Espinar-Barranco L, González-Vera JA, Orte A, Lavilla R, Vendrell M. RSC Chem Biol. 2022 Aug 25;3(10):1251-1259. doi: 10.1039/d2cb00168c.
miR-122 direct detection in human serum by time-gated fluorescence imaging. Garcia-Fernandez E, Gonzalez-Garcia MC, Pernagallo S, Ruedas-Rama MJ, Fara MA, López-Delgado FJ, Dear JW, Ilyine H, Ress C, Díaz-Mochón JJ, Orte A. Chem Commun (Camb). 2019 Dec 25;55(99):14958-14961. doi: 10.1039/c9cc08069d.
Synthesis, biological, and photophysical studies of molecular rotor-based fluorescent inhibitors of the trypanosome alternative oxidase. Cueto-Díaz EJ, Ebiloma GU, Alfayez IA, Ungogo MA, Lemgruber L, González-García MC, Giron MD, Salto R, Fueyo-González FJ, Shiba T, González-Vera JA, Ruedas Rama MJ, Orte A, de Koning HP, Dardonville C. Eur J Med Chem. 2021 Aug 5;220:113470. doi: 10.1016/j.ejmech.2021.113470.
Flow Synthesis of Biologically-Relevant Compound Libraries. Luque Navarro PM, Lanari D. Molecules. 2020 Feb 18;25(4):909. doi: 10.3390/molecules25040909.
Biological Evaluation of New Thienopyridinium and Thienopyrimidinium Derivatives as Human Choline Kinase Inhibitors. Luque-Navarro PM, Mariotto E, Ballarotto M, Rubbini G, Aguilar-Troyano FJ, Fasiolo A, Torretta A, Parisini E, Macchiarulo A, Laso A, Marco C, Viola G, Carrasco-Jimenez MP, López-Cara LC. Pharmaceutics. 2022 Mar 27;14(4):715. doi: 10.3390/pharmaceutics14040715.
Anticancer and Structure Activity Relationship of Non-Symmetrical Choline Kinase Inhibitors. Schiaffino-Ortega S, Mariotto E, Luque-Navarro PM, Kimatrai-Salvador M, Rios-Marco P, Hurtado-Guerrero R, Marco C, Carrasco-Jimenez MP, Viola G, López-Cara LC. Pharmaceutics. 2021 Aug 29;13(9):1360. doi: 10.3390/pharmaceutics13091360.
New Compounds with Bioisosteric Replacement of Classic Choline Kinase Inhibitors Show Potent Antiplasmodial Activity. Aguilar-Troyano FJ, Torretta A, Rubbini G, Fasiolo A, Luque-Navarro PM, Carrasco-Jimenez MP, Pérez-Moreno G, Bosch-Navarrete C, González-Pacanowska D, Parisini E, Lopez-Cara LC. Pharmaceutics. 2021 Nov 2;13(11):1842. doi: 10.3390/pharmaceutics13111842.
Changes in PRC1 activity during interphase modulate lineage transition in pluripotent cells. Asenjo HG, Alcazar-Fabra M, Espinosa-Martínez M, Lopez-Onieva L, Gallardo A, Dimitrova E, Feldmann A, Pachano T, Martorell-Marugán J, Carmona-Sáez P, Sanchez-Pozo A, Rada-Iglesias Á, Klose RJ, Landeira D. Nat Commun. 2023 Jan 12;14(1):180. doi: 10.1038/s41467-023-35859-9.
Orphan CpG islands amplify poised enhancer regulatory activity and determine target gene responsiveness. Pachano T, Sánchez-Gaya V, Ealo T, Mariner-Faulí M, Bleckwehl T, Asenjo HG, Respuela P, Cruz-Molina S, Muñoz-San Martín M, Haro E, van IJcken WFJ, Landeira D, Rada-Iglesias A. Nat Genet. 2021 Jul;53(7):1036-1049. doi: 10.1038/s41588-021-00888-x.
Polycomb regulation is coupled to cell cycle transition in pluripotent stem cells. Asenjo HG, Gallardo A, López-Onieva L, Tejada I, Martorell-Marugán J, Carmona-Sáez P, Landeira D. Sci Adv. 2020 Mar 4;6(10):eaay4768. doi: 10.1126/sciadv.aay4768
ADAMTS1 Supports Endothelial Plasticity of Glioblastoma Cells with Relevance for Glioma Progression. Serrano-Garrido O, Peris-Torres C, Redondo-García S, Asenjo HG, Plaza-Calonge MDC, Fernandez-Luna JL, Rodríguez-Manzaneque JC. Biomolecules. 2020 Dec 31;11(1):44. doi: 10.3390/biom11010044.
A Tri-Stimuli Responsive (Maghemite/PLGA)/Chitosan Nanostructure with Promising Applications in Lung Cancer. Fernández-Álvarez F, García-García G, Arias JL. Pharmaceutics. 2021 Aug 10;13(8):1232. doi: 10.3390/pharmaceutics13081232.
First steps in the formulation of praziquantel nanosuspensions for pharmaceutical applications. Martínez NA, Fernández-Álvarez F, Delgado ÁV, Badillo-García ML, Raba J, Cerutti SE, Arias JL. Pharm Dev Technol. 2020 Sep;25(7):892-898. doi: 10.1080/10837450.2020.1756320.
Engineering of stealth (maghemite/PLGA)/chitosan (core/shell)/shell nanocomposites with potential applications for combined MRI and hyperthermia against cancer. Fernández-Álvarez F, Caro C, García-García G, García-Martín ML, Arias JL. J Mater Chem B. 2021 Jun 23;9(24):4963-4980. doi: 10.1039/d1tb00354b.
Development and validation of a tool to measure collaborative practice between community pharmacists and physicians from the perspective of community pharmacists: the professional collaborative practice tool. Sanchez-Molina AI, Benrimoj SI, Ferri-Garcia R, Martinez-Martinez F, Gastelurrutia MA, Garcia-Cardenas V. BMC Health Serv Res. 2022 May 14;22(1):649. doi: 10.1186/s12913-022-08027.
Self-Assembled Lanthanide Antenna Glutathione Sensor for the Study of Immune Cells. Fueyo-González F, Espinar-Barranco L, Herranz R, Alkorta I, Crovetto L, Fribourg M, Paredes JM, Orte A, González-Vera JA. ACS Sens. 2022 Jan 28;7(1):322-330. doi: 10.1021/acssensors.1c02439.
Synthesis, Photophysics, and Solvatochromic Studies of an Aggregated-Induced-Emission Luminogen Useful in Bioimaging. Espinar-Barranco L, Meazza M, Linares-Perez A, Rios R, Paredes JM, Crovetto L. Sensors (Basel). 2019 Nov 12;19(22):4932. doi: 10.3390/s19224932.
New bioisosteric sulphur-containing choline kinase inhibitors with a tracked mode of action. Luque-Navarro PM, Carrasco-Jiménez MP, Goracci L, Paredes JM, Espinar-Barranco L, Valverde-Pozo J, Torretta A, Parisini E, Mariotto E, Marchioro C, Laso A, Marco C, Viola G, Lanari D, López Cara LC. Eur J Med Chem. 2023 Jan 15;246:115003. doi: 10.1016/j.ejmech.2022.115003.
A multicomponent reaction platform towards multimodal near-infrared BODIPY dyes for STED and fluorescence lifetime imaging. Fernandez A, Kielland N, Makda A, Carragher NO, González-García MC, Espinar-Barranco L, González-Vera JA, Orte A, Lavilla R, Vendrell M. RSC Chem Biol. 2022 Aug 25;3(10):1251-1259. doi: 10.1039/d2cb00168c.
Identification and heterologous expression of the globomycin biosynthetic gene cluster. Oves-Costales D, Gren T, Sterndorff EB, Martín J, Ortiz-López FJ, Jørgensen TS, Jiang X, Román-Hurtado F, Reyes F, Genilloud O, Weber T. Synth Syst Biotechnol. 2023 Feb 7;8(2):206-212. doi: 10.1016/j.synbio.2023.02.001.
Cacaoidin, First Member of the New Lanthidin RiPP Family. Ortiz-López FJ, Carretero-Molina D, Sánchez-Hidalgo M, Martín J, González I, Román-Hurtado F, de la Cruz M, García-Fernández S, Reyes F, Deisinger JP, Müller A, Schneider T, Genilloud O. Angew Chem Int Ed Engl. 2020 Jul 27;59(31):12654-12658. doi: 10.1002/anie.202005187.
Biosynthesis and Heterologous Expression of Cacaoidin, the First Member of the Lanthidin Family of RiPPs. Román-Hurtado F, Sánchez-Hidalgo M, Martín J, Ortiz-López FJ, Genilloud O. Antibiotics (Basel). 2021 Apr 8;10(4):403. doi: 10.3390/antibiotics10040403.
One Pathway, Two Cyclic Non-Ribosomal Pentapeptides: Heterologous Expression of BE-18257 Antibiotics and Pentaminomycins from Streptomyces cacaoi CA-170360. Román-Hurtado F, Sánchez-Hidalgo M, Martín J, Ortiz-López FJ, Carretero-Molina D, Reyes F, Genilloud O. Microorganisms. 2021 Jan 8;9(1):135. doi: 10.3390/microorganisms9010135.
Complete Genome Sequence of the Rare Actinobacterium Kutzneria sp. Strain CA-103260. Jørgensen TS, Gren T, Kontou EE, González I, Román-Hurtado F, Oves-Costales D, Thomsen E, Charusanti P, Genilloud O, Weber T. Microbiol Resour Announc. 2021 Jul 29;10(30):e0049921. doi: 10.1128/MRA.00499-21.
Prevalence, beliefs and impact of drug-drug interactions between antiretroviral therapy and illicit drugs among people living with HIV in Spain. Castro-Granell V, Garin N, Jaén Á, Cenoz S, Galindo MJ, Fuster-RuizdeApodaca MJ. PLoS One. 2021 Nov 19;16(11):e0260334. doi: 10.1371/journal.pone.0260334.
Recreational Drug Use in People Living with HIV in Spain: Factors Associated with Drug Use and the Impact on Clinical Outcomes. Castro-Granell V, Garin N, Jaén Á, Casado JL, Leal L, Cenoz S, Fuster-RuizdeApodaca MJ. AIDS Behav. 2021 Dec;25(12):3883-3897. doi: 10.1007/s10461-021-03271-3.
Drug use and antiretroviral therapy (ART) interactions: a qualitative study to explore the knowledge, beliefs, adherence, and quality of life of people living with HIV taking ART and illicit drugs. Fuster-RuizdeApodaca MJ, Castro-Granell V, Laguía A, Jaén Á, Cenoz S, Galindo MJ. AIDS Res Ther. 2020 May 24;17(1):24. doi: 10.1186/s12981-020-00279-y.
Prevalence and patterns of illicit drug use in people living with HIV in Spain: A cross-sectional study. Fuster-RuizdeApodaca MJ, Castro-Granell V, Garin N, Laguía A, Jaén Á, Iniesta C, Cenoz S, Galindo MJ. PLoS One. 2019 Jun 17;14(6):e0211252. doi: 10.1371/journal.pone.0211252.
Real clinical impact of drug-drug interactions of immunosuppressants in transplant patients. Gago-Sánchez AI, Font P, Cárdenas M, Aumente MD, Del Prado JR, Calleja MÁ. Pharmacol Res Perspect. 2021 Dec;9(6):e00892. doi: 10.1002/prp2.892.
Pharmaceutical care at discharge for patients with feeding tubes. López Gómez C, Arenas Villafranca JJ, Miranda Magaña M, Álvaro Sanz E, Moreno Santamaría M, Tortajada B. Nutr Hosp. 2022 Oct 17;39(5):971-976. doi: 10.20960/nh.04235
Systematic review of drug bioavailability following gastrointestinal surgery. Santamaría MM, Villafranca JJA, Abilés J, López AF, Rodas LV, Goitia BT, Navarro PU. Eur J Clin Pharmacol. 2018 Dec;74(12):1531-1545. doi: 10.1007/s00228-018-2539-9.
Effects of cyclic parenteral nutrition on parenteral-associated liver dysfunction parameters. Arenas Villafranca JJ, Nieto Guindo M, Álvaro Sanz E, Moreno Santamaria M, Garrido Siles M, Abilés J. Nutr J. 2017 Oct 4;16(1):66. doi: 10.1186/s12937-017-0289-7.
Impact of a nutrition consultation on the rate of high output stoma-related readmission: an ambispective cohort study. Santamaría MM, Villafranca JJA, Abilés J, Ruiz FR, Navarro PU, Goitia BT. Sci Rep. 2021 Aug 17;11(1):16620. doi: 10.1038/s41598-021-96136-7
Effect of genetic polymorphisms on therapeutic response in multiple sclerosis relapsing-remitting patients treated with interferon-beta. Martínez-Aguilar L, Pérez-Ramírez C, Maldonado-Montoro MDM, Carrasco-Campos MI, Membrive-Jiménez C, Martínez-Martínez F, García-Collado C, Calleja-Hernández MÁ, Ramírez-Tortosa MC, Jiménez-Morales A. Mutat Res Rev Mutat Res. 2020 Jul-Sep;785:108322. doi: 10.1016/j.mrrev.2020.108322.
Influence of Genetic Polymorphisms on Clinical Outcomes of Glatiramer Acetate in Multiple Sclerosis Patients. Zarzuelo-Romero MJ, Pérez-Ramírez C, Cura Y, Carrasco-Campos MI, Marangoni-Iglecias LM, Ramírez-Tortosa MC, Jiménez-Morales A. J Pers Med. 2021 Oct 15;11(10):1032. doi: 10.3390/jpm11101032.
Therapeutic Value of Single Nucleotide Polymorphisms on the Efficacy of New Therapies in Patients with Multiple Sclerosis. Zarzuelo Romero MJ, Pérez Ramírez C, Carrasco Campos MI, Sánchez Martín A, Calleja Hernández MÁ, Ramírez Tortosa MC, Jiménez Morales A. J Pers Med. 2021 Apr 23;11(5):335. doi: 10.3390/jpm11050335.
Pharmacogenetic Predictors of Response to Interferon Beta Therapy in Multiple Sclerosis. Carrasco-Campos MI, Pérez-Ramírez C, Macías-Cortés E, Puerta-García E, Sánchez-Pozo A, Arnal-García C, Barrero-Hernández FJ, Calleja-Hernández MÁ, Jiménez-Morales A, Cañadas-Garre M. Mol Neurobiol. 2021 Sep;58(9):4716-4726. doi: 10.1007/s12035-021-02454-2.
Degradation and in-use stability study of five marketed therapeutic monoclonal antibodies by generic weak cation exchange liquid chromatographic method ((WCX)HPLC/DAD). Martínez-Ortega A, Herrera A, Salmerón-García A, Cabeza J, Perez-Robles R, Navas N. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Jul 1;1203:123295. doi: 10.1016/j.jchromb.2022.123295.
Validated reverse phase HPLC diode array method for the quantification of intact bevacizumab, infliximab and trastuzumab for long-term stability study. Martínez-Ortega A, Herrera A, Salmerón-García A, Cabeza J, Cuadros-Rodríguez L, Navas N. Int J Biol Macromol. 2018 Sep;116:993-1003. doi: 10.1016/j.ijbiomac.2018.05.142
Study of aggregation in therapeutic monoclonal antibodies subjected to stress and long-term stability tests by analyzing size exclusion liquid chromatographic profiles. Hernández-Jiménez J, Martínez-Ortega A, Salmerón-García A, Cabeza J, Prados JC, Ortíz R, Navas N. Int J Biol Macromol. 2018 Oct 15;118(Pt A):511-524. doi: 10.1016/j.ijbiomac.2018.06.105.
Quantification of an intact monoclonal antibody, rituximab, by (RP)HPLC/DAD in compliance with ICH guidelines. Navas N, Herrera A, Martínez-Ortega A, Salmerón-García A, Cabeza J, Cuadros-Rodríguez L. Anal Bioanal Chem. 2013 Nov;405(29):9351-63. doi: 10.1007/s00216-013-7368-1.
Study and ICH validation of a reverse-phase liquid chromatographic method for the quantification of the intact monoclonal antibody cetuximab. Martínez-Ortega A, Herrera A, Salmerón-García A, Cabeza J, Cuadros-Rodríguez L, Navas N. J Pharm Anal. 2016 Apr;6(2):117-124. doi: 10.1016/j.jpha.2015.11.007.
Multimodal Chronic Pain Therapy for Adults via Smartphone: Randomized Controlled Clinical Trial. Morcillo-Muñoz Y, Sánchez-Guarnido AJ, Calzón-Fernández S, Baena-Parejo I. J Med Internet Res. 2022 May 11;24(5):e36114. doi: 10.2196/36114.
Multimodal Interventions to Improve the Management of Chronic Non-Malignant Pain in Primary Care Using Participatory Research. Morcillo-Muñoz Y, Castellano MHJ, Exposito FJD, Sanchez-Guarnido AJ, Alcantara MG, Baena-Parejo MI. Clin Pract. 2021 Aug 26;11(3):561-581. doi: 10.3390/clinpract11030072.
Strengthening patients' triage in community pharmacies: A cluster randomised controlled trial to evaluate the clinical impact of a minor ailment service. Amador-Fernández N, Benrimoj SI, Olry de Labry Lima A, García-Cárdenas V, Gastelurrutia MÁ, Berger J, Baixauli-Fernández VJ, Climent-Catalá MT, Colomer-Molina V, Martínez-Martínez F. PLoS One. 2022 Oct 25;17(10):e0275252. doi: 10.1371/journal.pone.0275252.
Identification of high-risk patients for referral through machine learning assisting the decision making to manage minor ailments in community pharmacies. Amador-Fernández N, Benrimoj SI, García-Cárdenas V, Gastelurrutia MÁ, Graham EL, Palomo-Llinares R, Sánchez-Tormo J, Baixauli Fernández VJ, Pérez Hoyos E, Plaza Zamora J, Colomer Molina V, Fuertes González R, García Agudo Ó, Martínez-Martínez F. Front Pharmacol. 2023 Jul 11;14:1105434. doi: 10.3389/fphar.2023.1105434.
A cost utility analysis alongside a cluster-randomised trial evaluating a minor ailment service compared to usual care in community pharmacy. Amador-Fernández N, Benrimoj SI, García-Mochón L, García-Cárdenas V, Dineen-Griffin S, Gastelurrutia MÁ, Gómez-Martínez JC, Colomer-Molina V, Martínez-Martínez F. BMC Health Serv Res. 2021 Nov 20;21(1):1253. doi: 10.1186/s12913-021-07188-4.
Patient Insight With Collagenase Treatment for Dupuytren: A Prospective Study. Sanjuan-Cervero R, Gomez-Herrero D, Peña-Molina F, de la Iglesia NH, Sanjuan-Arago A, Novoa-Parra CD. J Hand Surg Am. 2023 Dec;48(12):1274.e1-1274.e6. doi: 10.1016/j.jhsa.2022.04.013.
Sensitivity and Specificity of the Unité Rhumatologique Des Affections De La Main (URAM) Scale for Dupuytren Contracture: A Systematic Review and Meta-Analyses. Sanjuan-Cervero R, Gomez-Herrero D, Vazquez-Ferreiro P, Sanjuan-Arago A, Poquet-Jornet JE, Carrer-Hueso J. Cureus. 2022 Jan 26;14(1):e21636. doi: 10.7759/cureus.21636.
A comparison of patient-reported outcome measures for dupuytren disease: A prospective view. Sanjuan-Cervero R, Gomez-Herrero D, Poquet-Jornet JE, Peña-Molina F, de la Iglesia NH, Sanjuan-Arago A, Vazquez-Ferreiro P, Carrera-Hueso FJ. J Plast Reconstr Aesthet Surg. 2022 Oct;75(10):3774-3781. doi: 10.1016/j.bjps.2022.06.024.
“Validation of a spanish version of the 'Unité Rhumatologique Des Affections De La Main' (URAM) scale”. Gómez-Herrero D, Carrera-Hueso FJ, Sanjuan-Cerveró R, Montaner-Alonso D, Aguilella-Fernandez L, Vazquez-Ferreiro P, Poquet-Jornet JE, García-Jiménez E. J Plast Reconstr Aesthet Surg. 2021 Jul;74(7):1621-1628. doi: 10.1016/j.bjps.2020.11.024.
Effectiveness of direct-acting antiviral drugs against hepatitis C virus: predictive factors of response to the treatment. Cárdaba-García ME, Abad-Lecha E, Calleja-Hernández MÁ. Libyan J Med. 2021 Dec;16(1):1949797. doi: 10.1080/19932820.2021.1949797. Jesús Hermosilla Fernández
Comprehensive biophysical and functional study of ziv-aflibercept: characterization and forced degradation. Hermosilla J, Pérez-Robles R, Salmerón-García A, Casares S, Cabeza J, Bones J, Navas N. Sci Rep. 2020 Feb 14;10(1):2675. doi: 10.1038/s41598-020-59465-7.
Analysing the In-Use Stability of mRNA-LNP COVID-19 Vaccines Comirnaty™ (Pfizer) and Spikevax™ (Moderna): A Comparative Study of the Particulate. Hermosilla J, Alonso-García A, Salmerón-García A, Cabeza-Barrera J, Medina-Castillo AL, Pérez-Robles R, Navas N. Vaccines (Basel). 2023 Oct 25;11(11):1635. doi: 10.3390/vaccines11111635.
Stability study over time of clinical solutions of ziv-aflibercept prepared in infusion bags using a proper combination of physicochemical and functional strategies. Hermosilla J, Pérez-Robles R, Salmerón-García A, Casares S, Cabeza J, Navas N. J Pharm Biomed Anal. 2021 Sep 5;203:114209. doi: 10.1016/j.jpba.2021.114209.
Use of subcutaneous tocilizumab to prepare intravenous solutions for COVID-19 emergency shortage: Comparative analytical study of physicochemical quality attributes. Navas N, Hermosilla J, Torrente-López A, Hernández-Jiménez J, Cabeza J, Pérez-Robles R, Salmerón-García A. J Pharm Anal. 2020 Dec;10(6):532-545. doi: 10.1016/j.jpha.2020.06.003.
Comparative Stability Studies of Different Infliximab and Biosimilar CT-P13 Clinical Solutions by Combined Use of Physicochemical Analytical Techniques and Enzyme-Linked Immunosorbent Assay (ELISA). Hermosilla J, Sánchez-Martín R, Pérez-Robles R, Salmerón-García A, Casares S, Cabeza J, Cuadros-Rodríguez L, Navas N. BioDrugs. 2019 Apr;33(2):193-205. doi: 10.1007/s40259-019-00342-9.
RNase H2, mutated in Aicardi-Goutières syndrome, promotes LINE-1 retrotransposition. Benitez-Guijarro M, Lopez-Ruiz C, Tarnauskaitė Ž, Murina O, Mian Mohammad M, Williams TC, Fluteau A, Sanchez L, Vilar-Astasio R, Garcia-Canadas M, Cano D, Kempen MH, Sanchez-Pozo A, Heras SR, Jackson AP, Reijns MA, Garcia-Perez JL. EMBO J. 2018 Aug 1;37(15):e98506. doi: 10.15252/embj.201798506.
Synthesis and Characterization of Specific Reverse Transcriptase Inhibitors for Mammalian LINE-1 Retrotransposons. Banuelos-Sanchez G, Sanchez L, Benitez-Guijarro M, Sanchez-Carnerero V, Salvador-Palomeque C, Tristan-Ramos P, Benkaddour-Boumzaouad M, Morell S, Garcia-Puche JL, Heras SR, Franco-Montalban F, Tamayo JA, Garcia-Perez JL. Cell Chem Biol. 2019 Aug 15;26(8):1095-1109.e14. doi: 10.1016/j.chembiol.2019.04.010.
Systematic review of pragmatic randomised control trials assessing the effectiveness of professional pharmacy services in community pharmacies. Varas-Doval R, Saéz-Benito L, Gastelurrutia MA, Benrimoj SI, Garcia-Cardenas V, Martinez-Martínez F. BMC Health Serv Res. 2021 Feb 17;21(1):156. doi: 10.1186/s12913-021-06150-8.
Evaluating an implementation programme for medication review with follow-up in community pharmacy using a hybrid effectiveness study design: translating evidence into practice. Varas-Doval R, Gastelurrutia MA, Benrimoj SI, Zarzuelo MJ, Garcia-Cardenas V, Perez-Escamilla B, Martínez-Martínez F. BMJ Open. 2020 Sep 29;10(9):e036669. doi: 10.1136/bmjopen-2019-036669.
Clinical impact of a pharmacist-led medication review with follow up for aged polypharmacy patients: A cluster randomized controlled trial. Varas-Doval R, Gastelurrutia MA, Benrimoj SI, García-Cárdenas V, Sáez-Benito L, Martinez-Martínez F. Pharm Pract (Granada). 2020 Oct-Dec;18(4):2133. doi: 10.18549/PharmPract.2020.4.2133.
PEI-NIR Heptamethine Cyanine Nanotheranostics for Tumor Targeted Gene Delivery. De Los Reyes-Berbel E, Salto-Gonzalez R, Ortega-Muñoz M, Reche-Perez FJ, Jodar-Reyes AB, Hernandez-Mateo F, Giron-Gonzalez MD, Santoyo-Gonzalez F. Bioconjug Chem. 2018 Aug 15;29(8):2561-2575. doi: 10.1021/acs.bioconjchem.8b00262
Single chain variable fragment fused to maltose binding protein: a modular nanocarrier platform for the targeted delivery of antitumorals. Reche-Perez FJ, Plesselova S, De Los Reyes-Berbel E, Ortega-Muñoz M, Lopez-Jaramillo FJ, Hernandez-Mateo F, Santoyo-Gonzalez F, Salto-Gonzalez R, Giron-Gonzalez MD. Biomater Sci. 2021 Mar 10;9(5):1728-1738. doi: 10.1039/d0bm01903h.
Bioactive compounds of the Mediterranean diet and prostate cancer. López-Guarnido O, Urquiza-Salvat N, Saiz M, Lozano-Paniagua D, Rodrigo L, Pascual-Geler M, Lorente JA, Alvarez-Cubero MJ, Rivas A. Aging Male. 2018 Dec;21(4):251-260. doi: 10.1080/13685538.2018.1430129.
Adherence to Mediterranean diet and risk of prostate cancer. Urquiza-Salvat N, Pascual-Geler M, Lopez-Guarnido O, Rodrigo L, Martinez-Burgos A, Cozar JM, Ocaña-Peinado FM, Álvarez-Cubero MJ, Rivas A. Aging Male. 2019 Jun;22(2):102-108. doi: 10.1080/13685538.2018.1450854.
The influence of nutritional factors on prostate cancer incidence and aggressiveness. Pascual-Geler M, Urquiza-Salvat N, Cozar JM, Robles-Fernandez I, Rivas A, Martinez-Gonzalez LJ, Ocaña-Peinado FM, Lorente JA, Alvarez-Cubero MJ. Aging Male. 2018 Mar;21(1):31-39. doi: 10.1080/13685538.2017.1379491.
Analytical methods for the determination of emerging contaminants in sewage sludge samples. A review. Martín-Pozo L, de Alarcón-Gómez B, Rodríguez-Gómez R, García-Córcoles MT, Çipa M, Zafra-Gómez A. Talanta. 2019 Jan 15;192:508-533. doi: 10.1016/j.talanta.2018.09.056.
Assessing bioaccumulation potential of personal care, household and industrial products in a marine echinoderm (Holothuria tubulosa). Martín J, Hidalgo F, Alonso E, García-Corcoles MT, Vílchez JL, Zafra-Gómez A. Sci Total Environ. 2020 Jun 10;720:137668. doi: 10.1016/j.scitotenv.2020.137668.
Bioaccumulation of perfluoroalkyl substances in marine echinoderms: Results of laboratory-scale experiments with Holothuria tubulosa Gmelin, 1791. Martín J, Hidalgo F, García-Corcoles MT, Ibáñez-Yuste AJ, Alonso E, Vilchez JL, Zafra-Gómez A. Chemosphere. 2019 Jan;215:261-271. doi: 10.1016/j.chemosphere.2018.10.037.
Determination of quinolone residues in raw cow milk. Application of polar stir-bars and ultra-high performance liquid chromatography-tandem mass spectrometry. Rodríguez-Gómez R, García-Córcoles MT, Çipa M, Barrón D, Navalón A, Zafra-Gómez A. Food Addit Contam Part A Chem Anal Control Expo Risk Assess. 2018 Jun;35(6):1127-1138. doi: 10.1080/19440049.2018.1430382.
Gemcitabine-Loaded Magnetically Responsive Poly(ε-caprolactone) Nanoparticles against Breast Cancer. García-García G, Fernández-Álvarez F, Cabeza L, Delgado ÁV, Melguizo C, Prados JC, Arias JL. Polymers (Basel). 2020 Nov 25;12(12):2790. doi: 10.3390/polym12122790.
Multi-stimuli-responsive chitosan-functionalized magnetite/poly(ε-caprolactone) nanoparticles as theranostic platforms for combined tumor magnetic resonance imaging and chemotherapy. García-García G, Caro C, Fernández-Álvarez F, García-Martín ML, Arias JL. Nanomedicine. 2023 Aug;52:102695. doi: 10.1016/j.nano.2023.102695
A Tri-Stimuli Responsive (Maghemite/PLGA)/Chitosan Nanostructure with Promising Applications in Lung Cancer. Fernández-Álvarez F, García-García G, Arias JL. Pharmaceutics. 2021 Aug 10;13(8):1232. doi: 10.3390/pharmaceutics13081232.
Engineering of stealth (maghemite/PLGA)/chitosan (core/shell)/shell nanocomposites with potential applications for combined MRI and hyperthermia against cancer. Fernández-Álvarez F, Caro C, García-García G, García-Martín ML, Arias JL. J Mater Chem B. 2021 Jun 23;9(24):4963-4980. doi: 10.1039/d1tb00354b.
Discontinuation of cholinesterase inhibitor treatment in institutionalised patients with advanced dementia. García-García R, Calleja-Hernández MÁ. Eur J Hosp Pharm. 2022 May;29(3):145-150. doi: 10.1136/ejhpharm-2019-002106.
Impact of a risk-sharing agreement in rheumatoid arthritis in Spain. García-Collado CG, Martínez-de-la-Plata JE, Montoro MDMM, Morales AJ, Hernández MÁC, Martínez FM. Health Policy. 2021 Mar;125(3):335-340. doi: 10.1016/j.healthpol.2020.11.009.
Effect of DPYD, MTHFR, ABCB1, XRCC1, ERCC1 and GSTP1 on chemotherapy related toxicity in colorectal carcinoma. Puerta-García E, Urbano-Pérez D, Carrasco-Campos MI, Pérez-Ramírez C, Segura-Pérez A, Calleja-Hernández, Cañadas-Garre M. Surg Oncol. 2020 Dec;35:388-398. doi: 10.1016/j.suronc.2020.09.016.
Zeolites as Ingredients of Medicinal Products. Souza IMS, García-Villén F, Viseras C, Perger SBC. Pharmaceutics. 2023 Apr 28;15(5):1352. doi: 10.3390/pharmaceutics15051352.
Natural Inorganic Ingredients in Wound Healing. García-Villén F, Souza IMS, de Melo Barbosa R, Borrego-Sánchez A, Sánchez-Espejo R, Ojeda-Riascos S, Iborra CV. Curr Pharm Des. 2020;26(6):621-641. doi: 10.2174/1381612826666200113162114.
Study of Faujasite zeolite as a modified delivery carrier for isoniazid. Souza IMS, Borrego-Sánchez A, Sainz-Díaz CI, Viseras C, Pergher SBC. Mater Sci Eng C Mater Biol Appl. 2021 Jan;118:111365. doi: 10.1016/j.msec.2020.111365.
Can We Form Mesoporous Zeolites by Steam Assisted Crystallization of MCM-41? Souza IMS, Pergher SBC, Sachse A. Molecules. 2022 Dec 15;27(24):8934. doi: 10.3390/molecules27248934. Incorporation of Brazilian Diatomite in the Synthesis of An MFI Zeolite. Vinaches P, Schwanke AJ, Lopes CW, Souza IMS, Villarroel-Rocha J, Sapag K, Pergher SBC. Molecules. 2019 May 23;24(10):1980. doi: 10.3390/molecules24101980.
Receta electrónica: diferencias entre comunidades autónomas que afectan al acceso a los tratamientos y a la calidad de la atención farmacéutica. I. García Alfaro, JD. Carballeira Rodríguez. An. Sist. Sanit. Navar. 2020; 43(3): 297-306. doi.org/10.23938/ASSN.0880.
Receta electrónica: limitaciones y posibles mejoras para asegurar una mayor adherencia a los tratamientos. García Alfaro I, Carballeira Rodríguez JD. Rev Esp Salud Pública.2019;93: 25 de septiembre e201909070.
A comparative analysis of the pharmacovigilance systems of Brazil, Spain, the European Union and the United States based on the information provided by their regulatory agency websites. Leal MM, Sanz MM, Ferrando JRC, Martinez-Martinez F. Daru. 2019 Jun;27(1):379-387. doi: 10.1007/s40199-019-00249-4. Epub 2019 Feb 18.
Clay Minerals as Bioink Ingredients for 3D Printing and 3D Bioprinting: Application in Tissue Engineering and Regenerative Medicine. García-Villén F, Ruiz-Alonso S, Lafuente-Merchan M, Gallego I, Sainz-Ramos M, Saenz-Del-Burgo L, Pedraz JL. Pharmaceutics. 2021 Oct 28;13(11):1806. doi: 10.3390/pharmaceutics13111806.
Montmorillonite-norfloxacin nanocomposite intended for healing of infected wounds. García-Villén F, Faccendini A, Aguzzi C, Cerezo P, Bonferoni MC, Rossi S, Grisoli P, Ruggeri M, Ferrari F, Sandri G, Viseras C. Int J Nanomedicine. 2019 Jul 10;14:5051-5060. doi: 10.2147/IJN.S208713.
Safety of Nanoclay/Spring Water Hydrogels: Assessment and Mobility of Hazardous Elements. García-Villén F, Sánchez-Espejo R, Borrego-Sánchez A, Cerezo P, Perioli L, Viseras C. Pharmaceutics. 2020 Aug 12;12(8):764. doi: 10.3390/pharmaceutics12080764.
Correlation between Elemental Composition/Mobility and Skin Cell Proliferation of Fibrous Nanoclay/Spring Water Hydrogels. García-Villén F, Sánchez-Espejo R, Borrego-Sánchez A, Cerezo P, Cucca L, Sandri G, Viseras C. Pharmaceutics. 2020 Sep 18;12(9):891. doi: 10.3390/pharmaceutics12090891. Zeolites as Ingredients of Medicinal Products. Souza IMS, García-Villén F, Viseras C, Perger SBC. Pharmaceutics. 2023 Apr 28;15(5):1352. doi: 10.3390/pharmaceutics15051352.
Natural Inorganic Ingredients in Wound Healing. García-Villén F, Souza IMS, de Melo Barbosa R, Borrego-Sánchez A, Sánchez-Espejo R, Ojeda-Riascos S, Iborra CV. Curr Pharm Des. 2020;26(6):621-641. doi: 10.2174/1381612826666200113162114
Clay-Based Pharmaceutical Formulations and Drug Delivery Systems. García-Villén F, Viseras C. Pharmaceutics. 2020 Nov 25;12(12):1142. doi: 10.3390/pharmaceutics12121142. PMID: 33255689 Free PMC article.
Wound Healing Activity of Nanoclay/Spring Water Hydrogels. García-Villén F, Faccendini A, Miele D, Ruggeri M, Sánchez-Espejo R, Borrego-Sánchez A, Cerezo P, Rossi S, Viseras C, Sandri G. Pharmaceutics. 2020 May 21;12(5):467. doi: 10.3390/pharmaceutics12050467.
Comparative Metabolomics between Mycobacterium tuberculosis and the MTBVAC Vaccine Candidate. Díaz C, Pérez Del Palacio J, Valero-Guillén PL, Mena García P, Pérez I, Vicente F, Martín C, Genilloud O, Sánchez Pozo A, Gonzalo-Asensio J. ACS Infect Dis. 2019 Aug 9;5(8):1317-1326. doi: 10.1021/acsinfecdis.9b00008.
A novel in vitro approach for simultaneous evaluation of CYP3A4 inhibition and kinetic aqueous solubility. Pérez J, Díaz C, Asensio F, Palafox A, Genilloud O, Vicente F. J Biomol Screen. 2015 Feb;20(2):254-64. doi: 10.1177/1087057114552796.
High-Throughput Screening Platform for the Discovery of New Immunomodulator Molecules from Natural Product Extract Libraries. Pérez Del Palacio J, Díaz C, de la Cruz M, Annang F, Martín J, Pérez-Victoria I, González-Menéndez V, de Pedro N, Tormo JR, Algieri F, Rodriguez-Nogales A, Rodríguez-Cabezas ME, Reyes F, Genilloud O, Vicente F, Gálvez J. J Biomol Screen. 2016 Jul;21(6):567-78. doi: 10.1177/1087057116635517.
Bioactive imidamide-based compounds targeted against nitric oxide synthase. Arias F, Franco-Montalban F, Romero M, Duarte J, Dora Carrión M, Encarnación Camacho M. Bioorg Chem. 2022 Mar;120:105637. doi: 10.1016/j.bioorg.2022.105637.
NMR spectroscopy study of new imidamide derivatives as nitric oxide synthase inhibitors. Arias F, Camacho ME, Carrión MD. Magn Reson Chem. 2022 Sep;60(9):915-923. doi: 10.1002/mrc.5273. Epub 2022 Apr 25. PMID: 35428991 No abstract available.
Synthesis, bioevaluation and docking studies of new imidamide derivatives as nitric oxide synthase inhibitors. Arias F, Franco-Montalban F, Romero M, Carrión MD, Camacho ME. Bioorg Med Chem. 2021 Aug 15;44:116294. doi: 10.1016/j.bmc.2021.116294.
Antiglioma Activity of Aryl and Amido-Aryl Acetamidine Derivatives Targeting iNOS: Synthesis and Biological Evaluation. Maccallini C, Arias F, Gallorini M, Amoia P, Ammazzalorso A, De Filippis B, Fantacuzzi M, Giampietro L, Cataldi A, Camacho ME, Amoroso R. ACS Med Chem Lett. 2020 Jun 19;11(7):1470-1475. doi: 10.1021/acsmedchemlett.0c00285.
Quinazolinones, Quinazolinthiones, and Quinazolinimines as Nitric Oxide Synthase Inhibitors: Synthetic Study and Biological Evaluation. Camacho ME, Chayah M, García ME, Fernández-Sáez N, Arias F, Gallo MA, Carrión MD. Arch Pharm (Weinheim). 2016 Aug;349(8):638-50. doi: 10.1002/ardp.201600020.
* Gabriella Russo Russo Evaluation of the efficacy of EGF and hyaluronic acid formulation on periodontal defects named also black holes. Gabriella Russo, Javier Sánchez-Sánchez, Gloria González-Pérez, Ramón Gutiérrez-Sánchez, Rocío Amate-Marchal, Elena Sánchez-Fernández and Adolfina Ruiz-Martínez. Journal of Primary Health Care, Volume 4: 1-5. doi: 10.15761/HPC.1000181.
Development and Study of a Mucoadhesive Formulation with EGF and Hyaluronic Acid for Gum Application in Periodontitis. Gabriella Russo, Rocío Amate-Marchal, Herminia Castán, Elena Sánchez-Fernández and Adolfina Ruiz-Martínez. Biomedical Journal of Scientific &Technical Research, Volume 26- Issue 5. Doi: 0.26717/BJSTR.2020.26.004413.
Mineral profile of weight loss related foods marketed in Spain. Zurita-Ortega A, Cervera-Mata A, Delgado G, Zurita-Ortega F, Rufián-Henares JÁ, Pastoriza S. Food Chem. 2020 May 30;313:126156. doi: 10.1016/j.foodchem.2019.126156.